Patents by Inventor Cinzia INGALLINA

Cinzia INGALLINA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NOTCH INHIBITORS FOR USE IN THE TREATMENT OF T-CELL ACUTE LYMPHOBLASTIC LEUKEMIA
    Publication number: 20210363121
    Abstract: Compounds of formula (I) in the capacity of compounds with anti-tumor activity for the treatment of T-cell acute lymphoblastic leukemia (T-ALL).
    Type: Application
    Filed: August 9, 2021
    Publication date: November 25, 2021
    Inventors: Bruno Botta, Isabella Screpanti, Luca Tottone, Nadezda Zhdanoskaya, Cinzia Ingallina, Francesca Giulimondi, Deborah Quaglio, Rocco Palermo, Mattia Mori, Francesca Ghirga
  • Notch inhibitors for use in the treatment of t-cell acute lymphoblastic leukemia
    Patent number: 11104657
    Abstract: Compounds of formula (I) in the capacity of compounds with anti-tumor activity for the treatment of T-cell acute lymphoblastic leukemia (T-ALL).
    Type: Grant
    Filed: December 20, 2017
    Date of Patent: August 31, 2021
    Assignees: FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA, UNIVERSITÀ DEGLI STUDI DI ROMA “LA SAPIENZA”
    Inventors: Bruno Botta, Isabella Screpanti, Luca Tottone, Nadezda Zhdanoskaya, Cinzia Ingallina, Francesca Giulimondi, Deborah Quaglio, Rocco Palermo, Mattia Mori, Francesca Ghirga
  • COMPOUNDS FOR USE IN THE TREATMENT OF BRAIN DISEASES
    Publication number: 20210030714
    Abstract: The present invention relates to a compound of formula (1): or an analogue thereof or a pharmaceutically acceptable salt thereof, for use in the treatment of a brain tumor, wherein the compound is administered intranasally and relative pharmaceutical compositions.
    Type: Application
    Filed: February 5, 2019
    Publication date: February 4, 2021
    Applicants: UNIVERSITA DEGLI STUDI DI ROMA "LA SAPIENZA", FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA, UNIVERSITA DEGLIS STUDI DI PADOVA
    Inventors: Cristina LIMATOLA, Giuseppina D'ALESSANDRO, Lucia DI MARCOTULLIO, Paola INFANTE, Bruno BOTTA, Mattia MORI, Francesca GHIRGA, Cinzia INGALLINA, Simone BERARDOZZI, Paolo CALICETI, Stefano SALMASO, Michela DE MARTINO, Francesco GASPARRINI, Deborah QUAGLIO
  • NOTCH INHIBITORS FOR USE IN THE TREATMENT OF T-CELL ACUTE LYMPHOBLASTIC LEUKEMIA
    Publication number: 20190337916
    Abstract: Compounds of formula (I) in the capacity of compounds with anti-tumor activity for the treatment of T-cell acute lymphoblastic leukemia (T-ALL).
    Type: Application
    Filed: December 20, 2017
    Publication date: November 7, 2019
    Inventors: Bruno Botta, Isabella Screpanti, Luca Tottone, Nadezda Zhdanoskaya, Cinzia Ingallina, Francesca Giulimondi, Deborah Quaglio, Rocco Palermo, Mattia Mori, Francesca Ghirga
  • Multitarget hedgehog pathway inhibitors and uses thereof
    Patent number: 10093642
    Abstract: The present invention concerns compounds that selectively inhibit the activity of the Hedgehog (Hh) pathway, their preparation and uses thereof. The compounds of the present invention are useful in treating Hh-dependent tumors, such as medulloblastoma (MB).
    Type: Grant
    Filed: June 25, 2014
    Date of Patent: October 9, 2018
    Assignees: UNIVERSITÀ DEGLI STUDI DI ROMA “LA SAPIENZA”, UNIVERSITA DEGLI STUDI DI SIENA
    Inventors: Bruno Botta, Alberto Gulino, Maurizio Botta, Mattia Mori, Lucia Di Marcotullio, Paola Infante, Francesca Ghirga, Sara Toscano, Cinzia Ingallina, Romina Alfonsi
  • MULTITARGET HEDGEHOG PATHWAY INHIBITORS AND USES THEREOF
    Publication number: 20160368886
    Abstract: The present invention concerns compounds that selectively inhibit the activity of the Hedgehog (Hh) pathway, their preparation and uses thereof. The compounds of the present invention are useful in treating Hh-dependent tumors, such as medulloblastoma (MB).
    Type: Application
    Filed: June 25, 2014
    Publication date: December 22, 2016
    Applicant: Universita' Degli Studi di Siena
    Inventors: Bruno BOTTA, Alberto GULINO, Maurizio BOTTA, Mattia MORI, Lucia DI MARCOTULLIO, Paola INFANTE, Francesca GHIRGA, Sara TOSCANO, Cinzia INGALLINA, Romina ALFONSI