Patents by Inventor Cinzia Volonte'

Cinzia Volonte' has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of P2Y purinoreceptor antagonist for the treatment of ischemia reperfusion
    Patent number: 6559148
    Abstract: Use of compounds modulating P2 purinoceptors, in particular antagonists such as Basilen Blue E-3G (Reactive Blue 2), for the prevention of the damages due to global cerebral ischemia and ischemia-reperfusion. Said compounds reduce the mortality in case of global cerebral ischemia as well as the neuronal damage of the hippocampus.
    Type: Grant
    Filed: September 19, 2001
    Date of Patent: May 6, 2003
    Assignees: Consiglio Nazionale delle Ricerche, Fondazione Santa Lucia
    Inventors: Cinzia Volonte′, Giuseppe Sancesario, Giorgio Bernardi
  • Use of agonists or antagonists of P2 purinoceptors for the prevention glutamate-evoked cytotoxicity
    Publication number: 20020028790
    Abstract: Compounds that are agonists of P2 purinoceptors, such as 5-adenylylimidodiphosphate, are used to treat conditions such as pain, hormonal imbalance, high blood pressure, thermoregulation, respiration, learning, patter recognition and memory.
    Type: Application
    Filed: November 13, 2001
    Publication date: March 7, 2002
    Applicant: Consiglio Nazionale Delle Ricerche
    Inventors: Cinzia Volonte, Daniela Merlo
  • Use of agonists or antagonists of P2 purinoceptors for the prevention of glutamate-evoked cytotoxicity
    Patent number: 6326370
    Abstract: This invention relates to the use of agonists or antagonists of P2 purinoceptors for the prevention of glutamate-evoked cytotoxicity and in particular use of Basilen Blue D-3G (Reactive Blue 2), Cibacron Blue 3GA and 5-adenylylimidodiphosphate (AMPPNP). In the presence of cytotoxic concentrations of glutamate, these compounds sustain cellular survival of central nervous system (CNS) neurons, such as for example postnatal rat cerebellar granule neurons.
    Type: Grant
    Filed: March 18, 1998
    Date of Patent: December 4, 2001
    Assignee: Consiglio Nazionale Delle Recerche
    Inventors: Cinzia Volonte', Daniela Merlo