Patents by Inventor Clagett-Dame Margaret

Clagett-Dame Margaret has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • N-Cyclopropyl-(20R)-2-Methylene-19,26,27-Trinor-25-Aza-Vitamin D Analogs and Their Uses
    Publication number: 20120309713
    Abstract: This invention discloses N-cyclopropyl-(20R)-2-methylene-19,26,27-trinor-25-aza-vitamin D analogs, and specifically N-cyclopropyl-(20R)-2-methylene-19,26,27-trinor-25-aza-1?-hydroxyvitamin D3 and pharmaceutical uses therefor. This compound exhibits relatively high binding activity and pronounced activity in arresting the proliferation of undifferentiated cells and inducing their differentiation to the monocyte thus evidencing use as an anti-cancer agent especially for the treatment or prevention of leukemia, colon cancer, breast cancer, skin cancer or prostate cancer.
    Type: Application
    Filed: May 16, 2012
    Publication date: December 6, 2012
    Applicant: WISCONSIN ALUMNI RESEARCH FOUNDATION
    Inventors: DeLuca F. Hector, Clagett-Dame Margaret, Plum A. Lori, Chiellini Grazia