Patents by Inventor Claire DEO

Claire DEO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CHEMIGENETIC CALCIUM INDICATORS
    Publication number: 20230416320
    Abstract: A chemigenetic calcium indicator and a method of measuring calcium are provided. The chemigenetic calcium indicator includes a calcium-binding protein domain attached to a ligand binding protein domain. The method of measuring calcium includes administering a chemigenetic calcium indicator to a subject and determining changes in fluorescence, the chemigenetic calcium indicator including a ligand binding protein domain having a calcium-binding protein domain and a dye-ligand conjugate attached thereto.
    Type: Application
    Filed: June 7, 2023
    Publication date: December 28, 2023
    Inventors: Eric R. SCHREITER, Luke D. LAVIS, Claire DEO, Hersh BHARGAVA, Ahmed ABDELFATTAH
  • Chemigenetic calcium indicators
    Patent number: 11708397
    Abstract: A chemigenetic calcium indicator and a method of measuring calcium are provided. The chemigenetic calcium indicator includes a calcium-binding protein domain attached to a ligand binding protein domain. The method of measuring calcium includes administering a chemigenetic calcium indicator to a subject and determining changes in fluorescence, the chemigenetic calcium indicator including a ligand binding protein domain having a calcium-binding protein domain and a dye-ligand conjugate attached thereto.
    Type: Grant
    Filed: December 31, 2018
    Date of Patent: July 25, 2023
    Assignee: HOWARD HUGHES MEDICAL INSTITUTE
    Inventors: Eric R Schreiter, Luke D. Lavis, Claire Deo, Hersh Bhargava, Ahmed Abdelfattah
  • BRIGHT TARGETABLE RED CA2+ INDICATORS
    Publication number: 20230038702
    Abstract: The presently-disclosed subject matter includes fluorescent indicators, including bright and targetable red Ca2+ indicators. The presently-disclosed subject matter also includes kits comprising the same as well as methods for using the same to detect a target substance.
    Type: Application
    Filed: September 8, 2022
    Publication date: February 9, 2023
    Inventors: Luke D. LAVIS, Claire DEO
  • Bright targetable red CA indicators
    Patent number: 11498932
    Abstract: The presently-disclosed subject matter includes fluorescent indicators, including bright and targetable red Ca2+ indicators. The presently-disclosed subject matter also includes kits comprising the same as well as methods for using the same to detect a target substance.
    Type: Grant
    Filed: August 24, 2020
    Date of Patent: November 15, 2022
    Assignee: HOWARD HUGHES MEDICAL INSTITUTE
    Inventors: Luke D. Lavis, Claire Deo
  • BRIGHT TARGETABLE RED CA2+ INDICATORS
    Publication number: 20210054001
    Abstract: The presently-disclosed subject matter includes fluorescent indicators, including bright and targetable red Ca2+ indicators. The presently-disclosed subject matter also includes kits comprising the same as well as methods for using the same to detect a target substance.
    Type: Application
    Filed: August 24, 2020
    Publication date: February 25, 2021
    Inventors: Luke D. LAVIS, Claire DEO
  • CHEMIGENETIC CALCIUM INDICATORS
    Publication number: 20200317743
    Abstract: A chemigenetic calcium indicator and a method of measuring calcium are provided. The chemigenetic calcium indicator includes a calcium-binding protein domain attached to a ligand binding protein domain. The method of measuring calcium includes administering a chemigenetic calcium indicator to a subject and determining changes in fluorescence, the chemigenetic calcium indicator including a ligand binding protein domain having a calcium-binding protein domain and a dye-ligand conjugate attached thereto.
    Type: Application
    Filed: December 31, 2018
    Publication date: October 8, 2020
    Inventors: Eric R SCHREITER, Luke D. LAVIS, Claire DEO, Hersh BHARGAVA, Ahmed ABDELFATTAH