Patents by Inventor Claire E. Repellin

Claire E. Repellin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Polypeptide inhibitors of SMAD3 polypeptide activities
    Patent number: 10858654
    Abstract: This document provides polypeptide inhibitors of Smad3 polypeptide activities. For example, methods and materials for using polypeptides (e.g., polypeptides designed to include both a cell penetrating amino acid sequence and an amino acid segment of a SH3 domain of a SNX9 polypeptide) to inhibit one or more Smad3 polypeptide activities are provided. This document also provides methods and materials for using RNA interference to treat a disease (e.g., a fibrotic disease) in a mammal (e.g., a human).
    Type: Grant
    Filed: November 8, 2018
    Date of Patent: December 8, 2020
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Edward B. Leof, Mark C. Wilkes, Claire E. Repellin, Jeong-Han Kang, Xueqian Yin, Mahefatiana Andrianifahanana
  • POLYPEPTIDE INHIBITORS OF SMAD3 POLYPEPTIDE ACTIVITIES
    Publication number: 20190062747
    Abstract: This document provides polypeptide inhibitors of Smad3 polypeptide activities. For example, methods and materials for using polypeptides (e.g., polypeptides designed to include both a cell penetrating amino acid sequence and an amino acid segment of a SH3 domain of a SNX9 polypeptide) to inhibit one or more Smad3 polypeptide activities are provided. This document also provides methods and materials for using RNA interference to treat a disease (e.g., a fibrotic disease) in a mammal (e.g., a human).
    Type: Application
    Filed: November 8, 2018
    Publication date: February 28, 2019
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Edward B. Leof, Mark C. Wilkes, Claire E. Repellin, Jeong-Han Kang, Xueqian Yin, Mahefatiana Andrianifahanana
  • Polypeptide inhibitors of Smad3 polypeptide activities
    Patent number: 10144929
    Abstract: This document provides polypeptide inhibitors of Smad3 polypeptide activities. For example, methods and materials for using polypeptides (e.g., polypeptides designed to include both a cell penetrating amino acid sequence and an amino acid segment of a SH3 domain of a SNX9 polypeptide) to inhibit one or more Smad3 polypeptide activities are provided. This document also provides methods and materials for using RNA interference to treat a disease (e.g., a fibrotic disease) in a mammal (e.g., a human).
    Type: Grant
    Filed: February 7, 2017
    Date of Patent: December 4, 2018
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Edward B. Leof, Mark C. Wilkes, Claire E. Repellin, Jeong-Han Kang, Xueqian Yin, Mahefatiana Andrianifahanana
  • POLYPEPTIDE INHIBITORS OF SMAD3 POLYPEPTIDE ACTIVITIES
    Publication number: 20170253873
    Abstract: This document provides polypeptide inhibitors of Smad3 polypeptide activities. For example, methods and materials for using polypeptides (e.g., polypeptides designed to include both a cell penetrating amino acid sequence and an amino acid segment of a SH3 domain of a SNX9 polypeptide) to inhibit one or more Smad3 polypeptide activities are provided. This document also provides methods and materials for using RNA interference to treat a disease (e.g., a fibrotic disease) in a mammal (e.g., a human).
    Type: Application
    Filed: February 7, 2017
    Publication date: September 7, 2017
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Edward B. Leof, Mark C. Wilkes, Claire E. Repellin, Jeong-Han Kang, Xueqian Yin, Mahefatiana Andrianifahanana