Patents by Inventor Claire June Flynn

Claire June Flynn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pyrimidine derivatives as protein kinase inhibitors
    Patent number: 9493471
    Abstract: The present invention relates to pyrimidine derivatives capable of inhibiting one or more protein kinases. Further aspects relate to pharmaceutical compositions comprising the pyrimidine derivatives and the use thereof in the treatment of proliferative disorders.
    Type: Grant
    Filed: August 7, 2015
    Date of Patent: November 15, 2016
    Assignee: Cyclacel Limited
    Inventors: Jonathan James Hollick, Stuart Donald Jones, Claire June Flynn, Michael George Thomas
  • PYRIMIDINE DERIVATIVES AS PROTEIN KINASE INHIBITORS
    Publication number: 20150344486
    Abstract: The present invention relates to pyrimidine derivatives capable of inhibiting one or more protein kinases. Further aspects relate to pharmaceutical compositions comprising the pyrimidine derivatives and the use thereof in the treatment of proliferative disorders.
    Type: Application
    Filed: August 7, 2015
    Publication date: December 3, 2015
    Inventors: Jonathan James HOLLICK, Stuart Donald JONES, Claire June FLYNN, Michael George THOMAS
  • Pyrimidine derivatives as protein kinase inhibitors
    Patent number: 9133199
    Abstract: The present invention relates to a compound of formula (VII)I, or pharmaceutically acceptable salt or ester thereof, wherein: X is NR7; Y is O or N—(CH2)nR19; n is 1, 2 or 3; m is 1 or 2; R1 and R2 are each independently H, alkyl or cycloalkyl; R4 and R4? are each independently H or alkyl; or R4 and R4? together form a spiro cycloalkyl group; R19 is H, alkyl, aryl or a cycloalkyl group; R6 is OR8 or halogen; and R7 and R8 are each independently H or alkyl. Further aspects relate to pharmaceutical compositions comprising said compounds and use therefore in the treatment of proliferative disorders and the like.
    Type: Grant
    Filed: June 5, 2013
    Date of Patent: September 15, 2015
    Assignee: Cyclacel Limited
    Inventors: Jonathan James Hollick, Stuart Donald Jones, Claire June Flynn, Michael George Thomas
  • PYRIMIDINE DERIVATIVES AS PROTEIN KINASE INHIBITORS
    Publication number: 20140066436
    Abstract: The present invention relates to a compound of formula (VII)I, or pharmaceutically acceptable salt or ester thereof, wherein: X is NR7; Y is O or N—(CH2)nR19; n is 1, 2 or 3; m is 1 or 2; R1 and R2 are each independently H, alkyl or cycloalkyl; R4 and R4? are each independently H or alkyl; or R4 and R4? together form a spiro cycloalkyl group; R19 is H, alkyl, aryl or a cycloalkyl group; R6 is OR8 or halogen; and R7 and R8 are each independently H or alkyl. Further aspects relate to pharmaceutical compositions comprising said compounds and use therefore in the treatment of proliferative disorders and the like.
    Type: Application
    Filed: June 5, 2013
    Publication date: March 6, 2014
    Inventors: Jonathan James HOLLICK, Stuart Donald JONES, Claire June FLYNN, Michael George THOMAS
  • Pyrimidine derivatives as protein kinase inhibitors
    Patent number: 8563542
    Abstract: The present invention relates to a compound of formula (VII)I, or a pharmaceutically acceptable salt or ester thereof, wherein: X is NR7; Y is O or N—(CH2)nR19; n is 1, 2 or 3; m is 1 or 2; R1 and R2 are each independently H, alkyl or cycloalkyl; R4 and R4? each independently H alkyl; or R4 and R4? together form a spiro cycloalkyl group; R19 is H, alkyl, aryl or a cycloalkyl group; R6 is OR8 or halogen; and R7 and R8 are each independently H or alkyl. Further aspects relate to pharmaceutical compositions comprising said compounds and use therefore in the treatment of proliferative disorders and the like.
    Type: Grant
    Filed: September 29, 2008
    Date of Patent: October 22, 2013
    Assignee: Cyclacel Limited
    Inventors: Jonathan James Hollick, Stuart Donald Jones, Claire June Flynn, Michael George Thomas
  • PYRIMIDINE DERIVATIVES AS PROTEIN KINASE INHIBITORS
    Publication number: 20110046093
    Abstract: The present invention relates to a compound of formula (VII)I, or a pharmaceutically acceptable salt or ester thereof, wherein: X is NR7; Y is O or N—(CH2)nR19; n is 1, 2 or 3; m is 1 or 2; R1 and R2 are each independently H, alkyl or cycloalkyl; R4 and R4? each independently H alkyl; or R4 and R4? together form a spiro cycloalkyl group; R19 is H, alkyl, aryl or a cycloalkyl group; R6 is OR8 or halogen; and R7 and R8 are each independently H or alkyl. Further aspects relate to pharmaceutical compositions comprising said compounds and use therefore in the treatment of proliferative disorders and the like.
    Type: Application
    Filed: September 29, 2008
    Publication date: February 24, 2011
    Applicant: CYCLACEL LIMITED
    Inventors: Jonathan James Hollick, Stuart Donald Jones, Claire June Flynn, Michael George Thomas
  • Azabicycloalkane Derivatives Useful as Nicotinic Acetylcholine Receptor Agonists
    Publication number: 20080261999
    Abstract: Compounds of the formula I or a pharmaceutically acceptable salt thereof: processes for their preparation, pharmaceutical compositions which contain them and their uses in therapy.
    Type: Application
    Filed: February 23, 2006
    Publication date: October 23, 2008
    Inventors: Fionna Mitchell Martin, Claire June Flynn, Simon James Richards