Patents by Inventor Claire O'Connell

Claire O'Connell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • RNA target enrichment or depletion of biological samples
    Patent number: 12071616
    Abstract: A method of target enrichment or depletion from a sample with an analyte is described. A probe has one of a left-handed PNA pair and a targeting moiety, in which the left-handed PNA pair are a complementary pair of PNAs that are chiral and have a cyclic backbone modification that induces a left-handed helical structure. A capture surface has the other of the left-handed PNA pair; and the left-handed PNA pair bind to hybridize the probe to the capture surface, which may be a magnetic bead.
    Type: Grant
    Filed: March 5, 2021
    Date of Patent: August 27, 2024
    Assignees: Altratech Limited, The United States of America, as represented by the Secretary, Department of Health and Human Services
    Inventors: Brian O'Farrell, Claire O'Connell, Kaylyn Oshaben, Daniel Appella
  • RNA TARGET ENRICHMENT OR DEPLETION OF BIOLOGICAL SAMPLES
    Publication number: 20210277387
    Abstract: A method of target enrichment or depletion from a sample with an analyte is described. A probe has one of a left-handed PNA pair and a targeting moiety, in which the left-handed PNA pair are a complementary pair of PNAs that are chiral and have a cyclic backbone modification that induces a left-handed helical structure. A capture surface has the other of the left-handed PNA pair; and the left-handed PNA pair bind to hybridize the probe to the capture surface, which may be a magnetic bead.
    Type: Application
    Filed: March 5, 2021
    Publication date: September 9, 2021
    Inventors: Brian O'Farrell, Claire O'Connell, Kaylyn Oshaben, Daniel Appella