Patents by Inventor Claire S Przybyla

Claire S Przybyla has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of preparing retroviral protease inhibitor intermediates
    Patent number: 6849760
    Abstract: Chiral hydroxyethylamine, hydroxyethylurea or hydroxyethylsulfonamide isostere containing retroviral protease and renin inhibitors can be prepared by multi-step syntheses that utilize key chiral amine intermediates. This invention is a cost effective method of obtaining such key chiral amine intermediates enantiomerically, diastereomerically and chemically pure. The method is suitable for large scale (multikilogram) productions. This invention also encompasses organic acid and inorganic acid salts of the amine intermediates.
    Type: Grant
    Filed: December 23, 2002
    Date of Patent: February 1, 2005
    Assignee: G. D. Searle & Co.
    Inventors: John S Ng, Claire S Przybyla, Shu-Hong Zhang
  • Method of preparing retroviral protease inhibitor intermediates
    Patent number: 6515162
    Abstract: Chiral hydroxyethylamine, hydroxyethylurea or hydroxyethylsulfonamide isostere containing retroviral protease and renin inhibitors can be prepared by multi-step syntheses that utilize key chiral amine intermediates. This invention is a cost effective method of obtaining such key chiral amine intermediates enantiomerically, diastereomerically and chemically pure. The method is suitable for large scale (multikilogram) productions. This invention also encompasses organic acid and inorganic acid salts of the amine intermediates.
    Type: Grant
    Filed: December 21, 2000
    Date of Patent: February 4, 2003
    Assignee: G.D. Searle & Co.
    Inventors: John S Ng, Claire S. Przybyla, Shu-Hong Zhang
  • Method of preparing retroviral protease inhibitor intermediates
    Patent number: 6201150
    Abstract: Chiral hydroxyethylamine, hydroxyethylurea or hydroxyethylsulfonamide isostere containing retroviral protease and renin inhibitors can be prepared by multi-step syntheses that utilize key chiral amine intermediates. This invention is a cost effective method of obtaining such key chiral amine intermediates enantiomerically, diastereomerically and chemically pure. The method is suitable for large scale (multikilogram) productions. This invention also encompasses organic acid and inorganic acid salts of the amine intermediates.
    Type: Grant
    Filed: February 17, 1998
    Date of Patent: March 13, 2001
    Assignee: G.D. Searle & Co.
    Inventors: John S Ng, Claire S Przybyla, Shu-Hong Zhang