Patents by Inventor Claire Trecant

Claire Trecant has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Derivatives of morphine-6-glucuronide, preparation method thereof and use of same in therapeutics
    Patent number: 8461122
    Abstract: The disclosure relates to derivatives of morphine-6-glucuronide of formula (I) wherein R1 is as defined in the disclosure, or an acid addition salt thereof, as well as in hydrate or solvate form. The disclosure also relates to the preparation method thereof and to the use of same in therapeutics.
    Type: Grant
    Filed: June 8, 2011
    Date of Patent: June 11, 2013
    Assignee: Sanofi
    Inventors: Alain Dlubala, Claire Trecant, Isabelle Ripoche
  • Bicyclic derivatives of morphine-6-glucuronide, preparation method thereof and use of same in therapeutics
    Patent number: 8440634
    Abstract: The disclosure relates to compounds of formula (I): wherein R1, R2, and n are as defined in the disclosure, and addition salts solvates and hydrates thereof. The disclosure also relates to the preparation method of said compounds and to the use of the same in therapeutics.
    Type: Grant
    Filed: June 8, 2011
    Date of Patent: May 14, 2013
    Assignee: Sanofi
    Inventors: Alain Dlubala, Claire Trecant, Isabelle Ripoche
  • Synthesis of morphine-6-glucuronide or one of the derivatives thereof
    Patent number: 8258298
    Abstract: The disclosure relates to a method for preparing morphine-6-glucuronide or one of the deritives thereof comprising reacting a compound of formula (I): wherein R1 is as defined in the disclosure, with a glucuronic acid derivative of formula (II): wherein PG, X, and R4 are as defined in the disclosure, in the presence of an aromatic solvent and trimethylsilyl trifluoromethanesulfonate; (ii) reacting the product obtained in step (i) with a strong basic agent; and then (iii) recovering the product obtained in step (ii).
    Type: Grant
    Filed: June 8, 2011
    Date of Patent: September 4, 2012
    Assignee: Sanofi
    Inventors: Alain Dlubala, Claire Trecant, Isabelle Ripoche
  • DERIVATIVES OF MORPHINE-6-GLUCURONIDE, PREPARATION METHOD THEREOF AND USE OF SAME IN THERAPEUTICS
    Publication number: 20110301107
    Abstract: The disclosure relates to derivatives of morphine-6-glucuronide of formula (I) wherein R1 is as defined in the disclosure, or an acid addition salt thereof, as well as in hydrate or solvate form. The disclosure also relates to the preparation method thereof and to the use of same in therapeutics.
    Type: Application
    Filed: June 8, 2011
    Publication date: December 8, 2011
    Applicant: SANOFI
    Inventors: Alain DLUBALA, Claire TRECANT, Isabelle RIPOCHE
  • BICYCLIC DERIVATIVES OF MORPHINE-6-GLUCURONIDE, PREPARATION METHOD THEREOF AND USE OF SAME IN THERAPEUTICS
    Publication number: 20110275580
    Abstract: The disclosure relates to compounds of formula (I): wherein R1, R2, and n are as defined in the disclosure, and addition salts solvates and hydrates thereof. The disclosure also relates to the preparation method of said compounds and to the use of the same in therapeutics.
    Type: Application
    Filed: June 8, 2011
    Publication date: November 10, 2011
    Applicant: SANOFI
    Inventors: Alain DLUBALA, Claire TRECANT, Isabelle RIPOCHE
  • SYNTHESIS OF MORPHINE-6-GLUCURONIDE OR ONE OF THE DERIVATIVES THEREOF
    Publication number: 20110275820
    Abstract: The disclosure relates to a method for preparing morphine-6-glucuronide or one of the deritives thereof comprising reacting a compound of formula (I): wherein R1 is as defined in the disclosure, with a glucuronic acid derivative of formula (II): wherein PG, X, and R4 are as defined in the disclosure, in the presence of an aromatic solvent and trimethylsilyl trifluoromethanesulfonate; (ii) reacting the product obtained in step (i) with a strong basic agent; and then (iii) recovering the product obtained in step (ii).
    Type: Application
    Filed: June 8, 2011
    Publication date: November 10, 2011
    Applicant: SANOFI
    Inventors: Alain DLUBALA, Claire TRECANT, Isabelle RIPOCHE