Patents by Inventor Claire TSENG

Claire TSENG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240228583
    Abstract: The invention features polypeptides that include an extracellular ActRII chimera. In some embodiments, a polypeptide of the invention includes an extracellular ActRII chimera fused to an Fc domain or moiety. The invention also features pharmaceutical compositions and methods of using the polypeptides to treat diseases and conditions involving weakness or atrophy of muscles, bone damage, low red blood cell levels (e.g., anemia or blood loss), low platelet levels (e.g., thrombocytopenia), low neutrophil levels (e.g., neutropenia), fibrosis, metabolic disorders, pulmonary hypertension, and/or diseases and conditions that can be treated with erythropoietin or an erythropoiesis-stimulating agent.
    Type: Application
    Filed: May 3, 2022
    Publication date: July 11, 2024
    Inventors: Jasbir S. SEEHRA, Jennifer LACHEY, Claire TSENG, Elissa FURUTANI, Christopher R. ROVALDI
  • Publication number: 20230079602
    Abstract: The invention features polypeptides that include an extracellular ActRII chimera. In some embodiments, a polypeptide of the invention includes an extracellular ActRII chimera fused to an Fc domain monomer or moiety. The invention also features pharmaceutical compositions and methods of using the polypeptides to treat diseases and conditions involving weakness and atrophy of muscles, bone damage, low red blood cell levels (e.g., anemia or blood loss), low platelet levels (e.g., thrombocytopenia), low neutrophil levels (e.g., neutropenia), fibrosis, metabolic disorders, and/or pulmonary hypertension.
    Type: Application
    Filed: September 15, 2022
    Publication date: March 16, 2023
    Inventors: Jasbir S. SEEHRA, Jennifer LACHEY, Claire TSENG, Jason O'NEILL, Henning THØGERSEN, Elissa FURUTANI