Patents by Inventor Clara BELZER

Clara BELZER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20260199407
    Abstract: The present invention relates to pasteurized Akkermansia muciniphila or fragments thereof for treating a metabolic disorder in a subject in need thereof. The present invention also relates to a composition, a pharmaceutical composition and a medicament comprising pasteurized Akkermansia muciniphila or fragments thereof for treating a metabolic disorder. The present invention also relates to the use of pasteurized Akkermansia muciniphila or fragments thereof for promoting weight loss in a subject in need thereof.
    Type: Application
    Filed: November 20, 2025
    Publication date: July 16, 2026
    Inventors: Patrice CANI, Amandine EVERARD, Hubert PLOVIER, Céline DRUART, Willem DE VOS, Clara BELZER
  • Publication number: 20260174805
    Abstract: The present invention relates to Akkermansia muciniphila or fragments thereof for treating a metabolic disorder in a subject in need thereof. The present invention also relates to a composition, a pharmaceutical composition and a medicament comprising Akkermansia muciniphila or fragments thereof for treating a metabolic disorder. The present invention also relates to the use of Akkermansia muciniphila or fragments thereof for promoting weight loss in a subject in need thereof.
    Type: Application
    Filed: February 25, 2026
    Publication date: June 25, 2026
    Inventors: Patrice CANI, Amandine EVERARD, Clara BELZER, Willem DE VOS
  • Publication number: 20260166098
    Abstract: The present invention relates to pasteurized Akkermansia muciniphila or fragments thereof for treating a metabolic disorder in a subject in need thereof. The present invention also relates to a composition, a pharmaceutical composition and a medicament comprising pasteurized Akkermansia muciniphila or fragments thereof for treating a metabolic disorder. The present invention also relates to the use of pasteurized Akkermansia muciniphila or fragments thereof for promoting weight loss in a subject in need thereof.
    Type: Application
    Filed: October 16, 2025
    Publication date: June 18, 2026
    Inventors: Patrice CANI, Amandine EVERARD, Hubert PLOVIER, Céline DRUART, Willem DE VOS, Clara BELZER
  • Patent number: 12642821
    Abstract: The present invention relates to Akkermansia muciniphila or fragments thereof for treating a metabolic disorder in a subject in need thereof. The present invention also relates to a composition, a pharmaceutical composition and a medicament comprising Akkermansia muciniphila or fragments thereof for treating a metabolic disorder. The present invention also relates to the use of Akkermansia muciniphila or fragments thereof for promoting weight loss in a subject in need thereof.
    Type: Grant
    Filed: May 30, 2025
    Date of Patent: June 2, 2026
    Assignee: COMPAGNIE GERVAIS DANONE
    Inventors: Patrice Cani, Amandine Everard, Clara Belzer, Willem De Vos
  • Publication number: 20250288622
    Abstract: The present invention relates to Akkermansia muciniphila or fragments thereof for treating a metabolic disorder in a subject in need thereof. The present invention also relates to a composition, a pharmaceutical composition and a medicament comprising Akkermansia muciniphila or fragments thereof for treating a metabolic disorder. The present invention also relates to the use of Akkermansia muciniphila or fragments thereof for promoting weight loss in a subject in need thereof.
    Type: Application
    Filed: May 30, 2025
    Publication date: September 18, 2025
    Inventors: Patrice CANI, Amandine EVERARD, Clara BELZER, Willem DE VOS
  • Publication number: 20250288621
    Abstract: The present invention relates to Akkermansia muciniphila or fragments thereof for treating a metabolic disorder in a subject in need thereof. The present invention also relates to a composition, a pharmaceutical composition and a medicament comprising Akkermansia muciniphila or fragments thereof for treating a metabolic disorder. The present invention also relates to the use of Akkermansia muciniphila or fragments thereof for promoting weight loss in a subject in need thereof.
    Type: Application
    Filed: May 30, 2025
    Publication date: September 18, 2025
    Inventors: Patrice CANI, Amandine EVERARD, Clara BELZER, Willem DE VOS
  • Patent number: 11466057
    Abstract: It has been found that an extracellular polypeptide derived from Akkermansia municiphila is capable of modulating and/or promoting gut mucosal immune system function and/or maintaining and/or restoring metabolic status and/or increasing the physical integrity of the gut mucosal barrier in a mammal. The polypeptide or host cells comprising such polypeptide may be employed to prevent and/or treat a variety of conditions that benefit from an increased physical integrity of the gut mucosal barrier and/or an improved gut mucosal immune system function and metabolic status.
    Type: Grant
    Filed: June 30, 2020
    Date of Patent: October 11, 2022
    Assignees: WAGENINGEN UNIVERSITEIT, UNIVERSITÉ CATHOLIQUE DE LOUVAIN
    Inventors: Clara Belzer, Willem Meindert De Vos, Patrice Daniel Cani
  • Publication number: 20210393704
    Abstract: The present invention relates to Akkermansia muciniphila or fragments thereof for treating a metabolic disorder in a subject in need thereof. The present invention also relates to a composition, a pharmaceutical composition and a medicament comprising Akkermansia muciniphila or fragments thereof for treating a metabolic disorder. The present invention also relates to the use of Akkermansia muciniphila or fragments thereof for promoting weight loss in a subject in need thereof.
    Type: Application
    Filed: September 3, 2021
    Publication date: December 23, 2021
    Inventors: Patrice CANI, Amandine EVERARD, Clara BELZER, Willem DE VOS
  • Patent number: 11202807
    Abstract: A novel Akkermansia species has been isolated from fresh faeces obtained from the reticulated python. The species has been named Akkermansia glycaniphilus. It is capable of growing on mucus as a sole carbon and nitrogen source. The species can be used as a medicament, probiotic or cosmetic, e.g., for promoting weight loss, for promoting gut mucosal immune system function, for maintaining, restoring and/or increasing the physical integrity of the gut mucosal barrier, and for prevention or treatment of a variety of associated diseases or disorders.
    Type: Grant
    Filed: April 11, 2017
    Date of Patent: December 21, 2021
    Assignee: WAGENINGEN UNIVERSITEIT
    Inventors: Willem Meindert De Vos, Clara Belzer
  • Publication number: 20210322489
    Abstract: The present invention relates to Akkermansia muciniphila or fragments thereof for treating a metabolic disorder in a subject in need thereof. The present invention also relates to a composition, a pharmaceutical composition and a medicament comprising Akkermansia muciniphila or fragments thereof for treating a metabolic disorder. The present invention also relates to the use of Akkermansia muciniphila or fragments thereof for promoting weight loss in a subject in need thereof.
    Type: Application
    Filed: June 25, 2021
    Publication date: October 21, 2021
    Inventors: Patrice CANI, Amandine EVERARD, Clara BELZER, Willem DE VOS
  • Publication number: 20210188923
    Abstract: A method for cost-effectively and efficiently culturing Akkermansia muciniphila is described. High biomass yields can be obtained on chemically defined media. This allows for large scale production of A. muciniphila suitable for use in humans, such as for pharmaceutical or food applications. The A. muciniphila can be produced free of animal-derived products, thereby allowing a broad-range of applications.
    Type: Application
    Filed: March 5, 2021
    Publication date: June 24, 2021
    Inventors: Clara BELZER, Willem Meindert DE VOS
  • Publication number: 20210147489
    Abstract: It has been found that an extracellular polypeptide derived from Akkermansia municiphila is capable of modulating and/or promoting gut mucosal immune system function and/or maintaining and/or restoring metabolic status and/or increasing the physical integrity of the gut mucosal barrier in a mammal. The polypeptide or host cells comprising such polypeptide may be employed to prevent and/or treat a variety of conditions that benefit from an increased physical integrity of the gut mucosal barrier and/or an improved gut mucosal immune system function and metabolic status.
    Type: Application
    Filed: June 30, 2020
    Publication date: May 20, 2021
    Inventors: Clara BELZER, Willem Meindert DE VOS, Patrice Daniel CANI
  • Patent number: 10988509
    Abstract: A method for cost-effectively and efficiently culturing Akkermansia muciniphilais is disclosed. High biomass yields can be obtained on chemically defined media. This allows for large scale production of A. muciniphila suitable for use in humans, such as for pharmaceutical or food applications. The A. muciniphila can be produced free of animal-derived products, thereby allowing a broad-range of applications.
    Type: Grant
    Filed: May 4, 2016
    Date of Patent: April 27, 2021
    Assignee: WAGENINGEN UNIVERSITEIT
    Inventors: Clara Belzer, Willem Meindert De Vos
  • Publication number: 20210015876
    Abstract: The present invention relates to pasteurized Akkermansia muciniphila or fragments thereof for treating a metabolic disorder in a subject in need thereof. The present invention also relates to a composition, a pharmaceutical composition and a medicament comprising pasteurized Akkermansia muciniphila or fragments thereof for treating a metabolic disorder. The present invention also relates to the use of pasteurized Akkermansia muciniphila or fragments thereof for promoting weight loss in a subject in need thereof.
    Type: Application
    Filed: June 30, 2020
    Publication date: January 21, 2021
    Inventors: Patrice CANI, Amandine EVERARD, Hubert PLOVIER, Céline DRUART, Willem DE VOS, Clara BELZER
  • Patent number: 10738089
    Abstract: It has been found that an extracellular polypeptide derived from Akkermansia municiphila is capable of modulating and/or promoting gut mucosal immune system function and/or maintaining and/or restoring metabolic status and/or increasing the physical integrity of the gut mucosal barrier in a mammal. The polypeptide or host cells including such polypeptide may be employed to prevent and/or treat a variety of conditions that benefit from an increased physical integrity of the gut mucosal barrier and/or an improved gut mucosal immune system function and metabolic status.
    Type: Grant
    Filed: May 4, 2016
    Date of Patent: August 11, 2020
    Assignees: WAGENINGEN UNIVERSITEIT, UNIVERSITÉ CATHOLIQUE DE LOUVAIN
    Inventors: Clara Belzer, Willem Meindert De Vos, Patrice Daniel Cani
  • Patent number: 10736924
    Abstract: The present invention relates to pasteurized Akkermansia muciniphila or fragments thereof for treating a metabolic disorder in a subject in need thereof. The present invention also relates to a composition, a pharmaceutical composition and a medicament comprising pasteurized Akkermansia muciniphila or fragments thereof for treating a metabolic disorder. The present invention also relates to the use of pasteurized Akkermansia muciniphila or fragments thereof for promoting weight loss in a subject in need thereof.
    Type: Grant
    Filed: September 9, 2016
    Date of Patent: August 11, 2020
    Assignees: UNIVERSITÉ CATHOLIQUE DE LOUVAIN, WAGENINGEN UNIVERSITEIT
    Inventors: Patrice Cani, Amandine Everard, Hubert Plovier, Céline Druart, Willem De Vos, Clara Belzer
  • Publication number: 20200237833
    Abstract: The present invention relates to Akkermansia muciniphila or fragments thereof for treating a metabolic disorder in a subject in need thereof. The present invention also relates to a composition, a pharmaceutical composition and a medicament comprising Akkermansia muciniphila or fragments thereof for treating a metabolic disorder. The present invention also relates to the use of Akkermansia muciniphila or fragments thereof for promoting weight loss in a subject in need thereof.
    Type: Application
    Filed: December 20, 2019
    Publication date: July 30, 2020
    Inventors: Patrice CANI, Amandine EVERARD, Clara BELZER, Willem DE VOS
  • Publication number: 20200237832
    Abstract: The present invention relates to Akkermansia muciniphila or fragments thereof for treating a metabolic disorder in a subject in need thereof. The present invention also relates to a composition, a pharmaceutical composition and a medicament comprising Akkermansia muciniphila or fragments thereof for treating a metabolic disorder. The present invention also relates to the use of Akkermansia muciniphila or fragments thereof for promoting weight loss in a subject in need thereof.
    Type: Application
    Filed: December 20, 2019
    Publication date: July 30, 2020
    Inventors: Patrice CANI, Amandine EVERARD, Clara BELZER, Willem DE VOS
  • Publication number: 20200155616
    Abstract: The present invention relates to Akkermansia muciniphila or fragments thereof for treating a metabolic disorder in a subject in need thereof. The present invention also relates to a composition, a pharmaceutical composition and a medicament comprising Akkermansia muciniphila or fragments thereof for treating a metabolic disorder. The present invention also relates to the use of Akkermansia muciniphila or fragments thereof for promoting weight loss in a subject in need thereof.
    Type: Application
    Filed: December 10, 2019
    Publication date: May 21, 2020
    Inventors: Patrice CANI, Amandine EVERARD, Clara BELZER, Willem DE VOS
  • Publication number: 20200121737
    Abstract: The present invention relates to Akkermansia muciniphila or fragments thereof for treating a metabolic disorder in a subject in need thereof. The present invention also relates to a composition, a pharmaceutical composition and a medicament comprising Akkermansia muciniphila or fragments thereof for treating a metabolic disorder. The present invention also relates to the use of Akkermansia muciniphila or fragments thereof for promoting weight loss in a subject in need thereof.
    Type: Application
    Filed: December 10, 2019
    Publication date: April 23, 2020
    Inventors: Patrice CANI, Amandine EVERARD, Clara BELZER, Willem DE VOS