Patents by Inventor CLARA CHAN

CLARA CHAN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Mechanical phenotyping of single cells: high throughput quantitative detection and sorting
    Patent number: 10302408
    Abstract: This invention provides methods and devices for the high-throughput characterization of the mechanical properties of cells or particles. In certain embodiments the devices comprise a micro fluidic channel comprising: an oscillating element on a first side of said channel; and a detecting element on a second side of said channel opposite said oscillating element, wherein said detecting element is configured to detect a force transmitted through a cell or microparticle by said oscillating element. In certain embodiments the devices comprise a microfluidic channel comprising an integrated oscillator and sensor element on one first side of said channel, wherein said sensor is configured to detect a force transmitted through a cell or microparticle by said oscillator.
    Type: Grant
    Filed: November 5, 2013
    Date of Patent: May 28, 2019
    Assignee: The Regents of the University of California
    Inventors: Amy Rowat, David J. Hoelzle, Clara Chan
  • Mechanical phenotyping of single cells: high throughput quantitative detection and sorting
    Patent number: 9423234
    Abstract: This invention provides methods and devices for the high-throughput characterization of the mechanical properties of cells or particles. In certain embodiments the devices comprise a microfluidic channel comprising: an oscillating element on a first side of the channel; and a detecting element on a second side of the channel opposite the oscillating element, wherein the detecting element is configured to detect a force transmitted through a cell or microparticle by the oscillating element. In certain embodiments the devices comprise a microfluidic channel comprising an integrated oscillator and sensor element on one first side of the channel, wherein the sensor is configured to detect a force transmitted through a cell or microparticle by the oscillator.
    Type: Grant
    Filed: March 13, 2013
    Date of Patent: August 23, 2016
    Assignee: The Regents of the University of California
    Inventors: Amy Rowat, David J. Hoelzle, Clara Chan
  • MECHANICAL PHENOTYPING OF SINGLE CELLS: HIGH THROUGHPUT QUANTITATIVE DETECTION AND SORTING
    Publication number: 20150268029
    Abstract: This invention provides methods and devices for the high-throughput characterization of the mechanical properties of cells or particles. In certain embodiments the devices comprise a micro fluidic channel comprising: an oscillating element on a first side of said channel; and a detecting element on a second side of said channel opposite said oscillating element, wherein said detecting element is configured to detect a force transmitted through a cell or microparticle by said oscillating element. In certain embodiments the devices comprise a microfluidic channel comprising an integrated oscillator and sensor element on one first side of said channel, wherein said sensor is configured to detect a force transmitted through a cell or microparticle by said oscillator.
    Type: Application
    Filed: November 5, 2013
    Publication date: September 24, 2015
    Inventors: Amy Rowat, David J. Hoelzle, Clara Chan
  • MECHANICAL PHENOTYPING OF SINGLE CELLS: HIGH THROUGHPUT QUANTITATIVE DETECTION AND SORTING
    Publication number: 20140128285
    Abstract: This invention provides methods and devices for the high-throughput characterization of the mechanical properties of cells or particles. In certain embodiments the devices comprise a microfluidic channel comprising: an oscillating element on a first side of said channel; and a detecting element on a second side of said channel opposite said oscillating element, wherein said detecting element is configured to detect a force transmitted through a cell or microparticle by said oscillating element. In certain embodiments the devices comprise a microfluidic channel comprising an integrated oscillator and sensor element on one first side of said channel, wherein said sensor is configured to detect a force transmitted through a cell or microparticle by said oscillator.
    Type: Application
    Filed: March 13, 2013
    Publication date: May 8, 2014
    Inventors: AMY ROWAT, DAVID J. HOELZLE, CLARA CHAN