Patents by Inventor Clare Schmitt

Clare Schmitt has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Humanized monoclonal antibodies that protect against shiga toxin induced disease
    Publication number: 20070160607
    Abstract: The present invention describes the preparation and use of biologically and immunologically active humanized monoclonal antibodies to Shiga toxin, a toxin associated with HC and the potentially life-threatening sequela HUS transmitted by strains of pathogenic bacteria. The present invention describes how these humanized antibodies may be used in the treatment or prevention of Shiga toxin induced diseases. One aspect of the invention is the humanized monoclonal antibody which binds Shiga toxin where the constant regions are IgG1-kappa and the variable regions are murine in origin. Yet another aspect of the invention is expression vectors and host cells transformed with such vectors which express the humanized monoclonal antibodies of the present invention.
    Type: Application
    Filed: June 20, 2006
    Publication date: July 12, 2007
    Inventors: Jeffrey Stinson, Hing Wong, Alison O'Brien, Clare Schmitt, Angela Melton-Celsa
  • Humanized monoclonal antibodies that protect against shiga toxin induced disease
    Publication number: 20070003560
    Abstract: The present invention describes the preparation and use of biologically and immunologically active humanized monoclonal antibodies to Shiga toxin, a toxin associated with HC and the potentially life-threatening sequela HUS transmitted by strains of pathogenic bacteria. The present invention describes how these humanized antibodies may be used in the treatment or prevention of Shiga toxin induced diseases. One aspect of the invention is the humanized monoclonal antibody which binds Shiga toxin where the constant regions are IgG1-kappa and the variable regions are murine in origin. Yet another aspect of the invention is expression vectors and host cells transformed with such vectors which express the humanized monoclonal antibodies of the present invention.
    Type: Application
    Filed: June 20, 2006
    Publication date: January 4, 2007
    Inventors: Jeffrey Stinson, Hing Wong, Alison O'Brien, Clare Schmitt, Angela Melton-Celsa