Patents by Inventor Clarence A. Johnson
Clarence A. Johnson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9572882Abstract: The present invention relates to methods for supplementing the diet of subjects suffering from cardiovascular disease. D-Ribose is given long term alone or in combination with vasodilators in order to improve or maintain the diastolic or systolic function of the subjects.Type: GrantFiled: June 26, 2009Date of Patent: February 21, 2017Assignee: RiboCor, INC.Inventors: Terri L. Butler, John St. Cyr, Clarence A. Johnson
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Patent number: 8759315Abstract: A ribose-related compound is added to whole blood or packed red cells which have suboptimal function as measured by decreased levels of 2,3-DPG in order to rejuvenate the red blood cells to normal function as seen by raised levels of 2,3-DPG. Two representative ribose-related compounds are D-ribose and inosine.Type: GrantFiled: January 5, 2007Date of Patent: June 24, 2014Assignee: Viacell, LLCInventors: John A St. Cyr, Daniel G Ericson, Clarence A Johnson
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Patent number: 7687468Abstract: D-Ribose, a buffer and an anticoagulant are added to whole blood or packed red cells to extend function in storage beyond 42 days. Methods are disclosed to rejuvenate suboptimally functional red cells. The methods are comprised of incubation of the cells at 37° C. for 10 to 60 minutes in the presence of D-ribose.Type: GrantFiled: May 14, 2003Date of Patent: March 30, 2010Assignee: Viacell, LLC.Inventors: John A. St. Cyr, Daniel G. Ericson, Clarence A. Johnson
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Publication number: 20100009924Abstract: The present invention relates to methods for supplementing the diet of subjects suffering from cardiovascular disease. D-Ribose is given long term alone or in combination with vasodilators in order to improve or maintain the diastolic or systolic function of the subjects.Type: ApplicationFiled: June 26, 2009Publication date: January 14, 2010Applicant: Bioenergy, Inc.Inventors: Terri L. Butler, John St. Cyr, Clarence A. Johnson
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Patent number: 7553817Abstract: The present invention relates to compositions for supplementing the diet of subjects suffering from cardiovascular or peripheral vascular disease or those at risk for such conditions. Ribose is given alone or in combination with one or a combination of vasodilators, nutrients and vitamins. Preferred vitamins include Vitamins C, B6, B12 and folic acid. Preferred nutrients include glutamine and glucose.Type: GrantFiled: October 23, 2003Date of Patent: June 30, 2009Assignee: Bioenergy, Inc.Inventors: Terri L. Butler, John St. Cyr, Clarence A. Johnson
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Publication number: 20040229204Abstract: D-Ribose, a buffer and an anticoagulant are added to whole blood or packed red cells to extend function in storage beyond 42 days. Methods are disclosed to rejuvenate suboptimally functional red cells. The methods are comprised of incubation of the cells at 37° C. for 10 to 60 minutes in the presence of D-ribose.Type: ApplicationFiled: May 14, 2003Publication date: November 18, 2004Inventors: John A. St. Cyr, Daniel G. Ericson, Clarence A. Johnson
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Publication number: 20040087515Abstract: The present invention relates to compositions for supplementing the diet of subjects suffering from cardiovascular or peripheral vascular disease or those at risk for such conditions. Ribose is given alone or in combination with one or a combination of vasodilators, nutrients and vitamins. Preferred vitamins include Vitamins C, B6, B12 and folic acid. Preferred nutrients include glutamine and glucose.Type: ApplicationFiled: October 23, 2003Publication date: May 6, 2004Inventors: Terri L. Butler, John St. Cyr, Clarence A. Johnson
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Patent number: 6663859Abstract: D-Ribose and methods for using D-Ribose are provided for enhancing the immune response in mammals. Those with a less than optimal immune response will benefit from oral or parenteral administration of D-Ribose. Methods are also provided for the enhancement of the immune response in isolated leukocytes. Leukocytes are cultured ex vivo in the presence of D-Ribose and transfused into a patient in need of leukocyte augmentation.Type: GrantFiled: January 8, 2001Date of Patent: December 16, 2003Assignees: Bioenergy, Inc., University of FloridaInventors: Susan S. Percival, Robin J. Henken, John St. Cyr, Clarence A. Johnson, Terri L. Butler
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Patent number: 6534480Abstract: Precursors of adenosine triphosphate are administered orally to increase intracellular ATP concentration as dietary supplements or for treatment of reduced energy availability resulting from strenuous physical activity, illness or trauma. Pentose sugars are administered individually, mixed into dry food or in solution. The preferred pentose is D-ribose, singly or combined with creatine, pyruvate, L-carnitine and/or vasodilating agents. Additionally, magnesium, electrolytes, fatty acids and hexose sugars can be used. The compositions and methods of this invention are especially beneficial to mammals having reduced energy availability or high energy demand.Type: GrantFiled: December 18, 2000Date of Patent: March 18, 2003Assignee: Bioenergy Inc.Inventors: John St. Cyr, Clarence A. Johnson
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Patent number: 6511964Abstract: Persons encountering high altitudes without being acclimatized can prevent or alleviate the symptoms of acute mountain sickness by administration of ribose one to four times a days, beginning immediately on encountering high altitudes and continuing for at least five days.Type: GrantFiled: March 29, 2001Date of Patent: January 28, 2003Assignee: Bioenergy, Inc.Inventors: Terri L. Butler, John St. Cyr, Clarence A. Johnson
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Publication number: 20020119933Abstract: The present invention relates to compositions for supplementing the diet of subjects suffering from cardiovascular or peripheral vascular disease or those at risk for such conditions. Ribose is given alone or in combination with one or a combination of vasodilators, nutrients and vitamins. Preferred vitamins include Vitamins C, B6, B12 and folic acid. Preferred nutrients include glutamine and glucose.Type: ApplicationFiled: July 27, 2001Publication date: August 29, 2002Inventors: Terri L. Butler, John St. Cyr, Clarence A. Johnson
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Patent number: 6429198Abstract: Pentose is administered to mammals to increase athletic performance and reduce fatigue.Type: GrantFiled: October 3, 2000Date of Patent: August 6, 2002Assignee: Bioenergy Inc.Inventors: John St. Cyr, Clarence A. Johnson, Scott Hagerman, Louis W. Vasquez, Terri L. Butler
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Publication number: 20020072501Abstract: Precursors of adenosine triphosphate are administered orally to increase intracellular ATP concentration as dietary supplements or for treatment of reduced energy availability resulting from strenuous physical activity, illness or trauma. Pentose sugars are administered individually, mixed into dry food or in solution. The preferred pentose is D-ribose, singly or combined with creatine, pyruvate, L-carnitine and/or vasodilating agents. Additionally, magnesium, electrolytes, fatty acids and hexose sugars can be used. The compositions and methods of this invention are especially beneficial to mammals having reduced energy availability or high energy demand.Type: ApplicationFiled: December 18, 2000Publication date: June 13, 2002Inventors: John St. Cyr, Clarence A. Johnson
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Publication number: 20020065232Abstract: Persons encountering high altitudes without being acclimatized can prevent or alleviate the symptoms of acute mountain sickness by administration of ribose one to four times a days, beginning immediately on encountering high altitudes and continuing for at least five days.Type: ApplicationFiled: March 29, 2001Publication date: May 30, 2002Inventors: Terri L. Butler, John St. Cyr, Clarence A. Johnson
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Publication number: 20020028196Abstract: D-Ribose and methods for using D-Ribose are provided for enhancing the immune response in mammals. Those with a less than optimal immune response will benefit from oral or parenteral administration of D-Ribose. Methods are also provided for the enhancement of the immune response in isolated leukocytes. Leukocytes are cultured ex vivo in the presence of D-Ribose and transfused into a patient in need of leukocyte augmentation.Type: ApplicationFiled: January 8, 2001Publication date: March 7, 2002Inventors: Susan S. Percival, Robin J. Henken, John St. Cyr, Clarence A. Johnson, Terri L. Butler
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Patent number: 6339716Abstract: A method of determining the viability of a hibernating or stunned myocardial segment comprises the administration of ribose, a vasodilator and an inotropic agent. The preferred agent is dobutamine, which has both a vasodilation and an inotropic effect. The segments may be identified by myocardial imaging by any known means, such as echocardiography, Thallium-201 tracing or positron emission tomography. Ribose is preferably given one minute to three hours prior to administration of the vasodilator and inotropic agents.Type: GrantFiled: September 24, 1999Date of Patent: January 15, 2002Assignee: Bioenergy Inc.Inventors: Stephen G. Sawada, John St. Cyr, Clarence A. Johnson
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Patent number: 6218366Abstract: The administration of ribose raises the hypoxic threshold of mammals experiencing a hypoxic condition. The presence of an effective amount of ribose in the tissue of a mammal increases the tolerance to hypoxia and decreases the symptoms of hypoxia in mammals experiencing chronic hypoxia due to cardiovascular disease or peripheral vascular disease. Such mammals are additionally benefited by administration of ribose and a vasodilator or an isotropic agent. Mammals experiencing transient hypoxia from high altitude, anesthesia or exercise are also benefited.Type: GrantFiled: September 24, 1999Date of Patent: April 17, 2001Assignee: Bioenergy, Inc.Inventors: John St. Cyr, Clarence A. Johnson, Dean J. MacCarter, Stephen G. Sawada
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Patent number: 6159942Abstract: Precursors of adenosine triphosphate are administered orally to increase intracellular ATP concentration as dietary supplements or for treatment of reduced energy availability resulting from strenuous physical activity, illness or trauma. Pentose sugars are administered individually, mixed into dry food or in solution. The preferred pentose is D-ribose, singly or combined with creatine, pyruvate, L-carnitine and/or vasodilating agents. Additionally, magnesium, electrolytes, fatty acids and hexose sugars can be used. The compositions and methods of this invention are especially beneficial to mammals having reduced energy availability or high energy demand.Type: GrantFiled: April 12, 1999Date of Patent: December 12, 2000Assignee: Bioenergy, Inc.Inventors: John St. Cyr, Clarence A. Johnson
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Patent number: 4099933Abstract: The gasification of coal to produce a methane-rich product gas is accomplished through the controlled slow heating of particulate coal in a gasifier comprising two or more zones, whereby any significant decrease in the density of the coal particles is minimized and particle swelling and friability are significantly reduced, while the carryover of fines and deposition of tars in the product gas conduit are thereby minimized. The particulate coal heating rate in the gasifier zones is usually between about 10.degree. and 200.degree. F per minute. When the particulate coal is to be fed to the gasifier at elevated temperature, further improvements are achieved with swelling type caking coals through their pretreatment by preheating the coal at a slow rate between 10.degree. and 100.degree. F per minute up to about 800.degree. F in multiple fluidized beds.Type: GrantFiled: June 10, 1975Date of Patent: July 11, 1978Assignee: Hydrocarbon Research, Inc.Inventors: Clarence A. Johnson, John Shen
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Patent number: 3985516Abstract: Low rank coals such as subbituminous or lignites containing more than about 10 wt. % moisture are first dried and then passed to a fluidized bed where the coal is passivated against reabsorption of moisture by coating the warm coal particles with a heavy liquid hydrocarbon material. Such coating substantially prevents the reabsorption of moisture in the coal, and thereby prevents autogenous heating and possible spontaneous ignition during subsequent transportation or storage of the passivated coal.Type: GrantFiled: August 20, 1975Date of Patent: October 12, 1976Assignee: Hydrocarbon Research, Inc.Inventors: Clarence A. Johnson, William Volk