Patents by Inventor Clarence A. Johnson

Clarence A. Johnson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9572882
    Abstract: The present invention relates to methods for supplementing the diet of subjects suffering from cardiovascular disease. D-Ribose is given long term alone or in combination with vasodilators in order to improve or maintain the diastolic or systolic function of the subjects.
    Type: Grant
    Filed: June 26, 2009
    Date of Patent: February 21, 2017
    Assignee: RiboCor, INC.
    Inventors: Terri L. Butler, John St. Cyr, Clarence A. Johnson
  • Patent number: 8759315
    Abstract: A ribose-related compound is added to whole blood or packed red cells which have suboptimal function as measured by decreased levels of 2,3-DPG in order to rejuvenate the red blood cells to normal function as seen by raised levels of 2,3-DPG. Two representative ribose-related compounds are D-ribose and inosine.
    Type: Grant
    Filed: January 5, 2007
    Date of Patent: June 24, 2014
    Assignee: Viacell, LLC
    Inventors: John A St. Cyr, Daniel G Ericson, Clarence A Johnson
  • Patent number: 7687468
    Abstract: D-Ribose, a buffer and an anticoagulant are added to whole blood or packed red cells to extend function in storage beyond 42 days. Methods are disclosed to rejuvenate suboptimally functional red cells. The methods are comprised of incubation of the cells at 37° C. for 10 to 60 minutes in the presence of D-ribose.
    Type: Grant
    Filed: May 14, 2003
    Date of Patent: March 30, 2010
    Assignee: Viacell, LLC.
    Inventors: John A. St. Cyr, Daniel G. Ericson, Clarence A. Johnson
  • Publication number: 20100009924
    Abstract: The present invention relates to methods for supplementing the diet of subjects suffering from cardiovascular disease. D-Ribose is given long term alone or in combination with vasodilators in order to improve or maintain the diastolic or systolic function of the subjects.
    Type: Application
    Filed: June 26, 2009
    Publication date: January 14, 2010
    Applicant: Bioenergy, Inc.
    Inventors: Terri L. Butler, John St. Cyr, Clarence A. Johnson
  • Patent number: 7553817
    Abstract: The present invention relates to compositions for supplementing the diet of subjects suffering from cardiovascular or peripheral vascular disease or those at risk for such conditions. Ribose is given alone or in combination with one or a combination of vasodilators, nutrients and vitamins. Preferred vitamins include Vitamins C, B6, B12 and folic acid. Preferred nutrients include glutamine and glucose.
    Type: Grant
    Filed: October 23, 2003
    Date of Patent: June 30, 2009
    Assignee: Bioenergy, Inc.
    Inventors: Terri L. Butler, John St. Cyr, Clarence A. Johnson
  • Publication number: 20040229204
    Abstract: D-Ribose, a buffer and an anticoagulant are added to whole blood or packed red cells to extend function in storage beyond 42 days. Methods are disclosed to rejuvenate suboptimally functional red cells. The methods are comprised of incubation of the cells at 37° C. for 10 to 60 minutes in the presence of D-ribose.
    Type: Application
    Filed: May 14, 2003
    Publication date: November 18, 2004
    Inventors: John A. St. Cyr, Daniel G. Ericson, Clarence A. Johnson
  • Publication number: 20040087515
    Abstract: The present invention relates to compositions for supplementing the diet of subjects suffering from cardiovascular or peripheral vascular disease or those at risk for such conditions. Ribose is given alone or in combination with one or a combination of vasodilators, nutrients and vitamins. Preferred vitamins include Vitamins C, B6, B12 and folic acid. Preferred nutrients include glutamine and glucose.
    Type: Application
    Filed: October 23, 2003
    Publication date: May 6, 2004
    Inventors: Terri L. Butler, John St. Cyr, Clarence A. Johnson
  • Patent number: 6663859
    Abstract: D-Ribose and methods for using D-Ribose are provided for enhancing the immune response in mammals. Those with a less than optimal immune response will benefit from oral or parenteral administration of D-Ribose. Methods are also provided for the enhancement of the immune response in isolated leukocytes. Leukocytes are cultured ex vivo in the presence of D-Ribose and transfused into a patient in need of leukocyte augmentation.
    Type: Grant
    Filed: January 8, 2001
    Date of Patent: December 16, 2003
    Assignees: Bioenergy, Inc., University of Florida
    Inventors: Susan S. Percival, Robin J. Henken, John St. Cyr, Clarence A. Johnson, Terri L. Butler
  • Patent number: 6534480
    Abstract: Precursors of adenosine triphosphate are administered orally to increase intracellular ATP concentration as dietary supplements or for treatment of reduced energy availability resulting from strenuous physical activity, illness or trauma. Pentose sugars are administered individually, mixed into dry food or in solution. The preferred pentose is D-ribose, singly or combined with creatine, pyruvate, L-carnitine and/or vasodilating agents. Additionally, magnesium, electrolytes, fatty acids and hexose sugars can be used. The compositions and methods of this invention are especially beneficial to mammals having reduced energy availability or high energy demand.
    Type: Grant
    Filed: December 18, 2000
    Date of Patent: March 18, 2003
    Assignee: Bioenergy Inc.
    Inventors: John St. Cyr, Clarence A. Johnson
  • Patent number: 6511964
    Abstract: Persons encountering high altitudes without being acclimatized can prevent or alleviate the symptoms of acute mountain sickness by administration of ribose one to four times a days, beginning immediately on encountering high altitudes and continuing for at least five days.
    Type: Grant
    Filed: March 29, 2001
    Date of Patent: January 28, 2003
    Assignee: Bioenergy, Inc.
    Inventors: Terri L. Butler, John St. Cyr, Clarence A. Johnson
  • Publication number: 20020119933
    Abstract: The present invention relates to compositions for supplementing the diet of subjects suffering from cardiovascular or peripheral vascular disease or those at risk for such conditions. Ribose is given alone or in combination with one or a combination of vasodilators, nutrients and vitamins. Preferred vitamins include Vitamins C, B6, B12 and folic acid. Preferred nutrients include glutamine and glucose.
    Type: Application
    Filed: July 27, 2001
    Publication date: August 29, 2002
    Inventors: Terri L. Butler, John St. Cyr, Clarence A. Johnson
  • Patent number: 6429198
    Abstract: Pentose is administered to mammals to increase athletic performance and reduce fatigue.
    Type: Grant
    Filed: October 3, 2000
    Date of Patent: August 6, 2002
    Assignee: Bioenergy Inc.
    Inventors: John St. Cyr, Clarence A. Johnson, Scott Hagerman, Louis W. Vasquez, Terri L. Butler
  • Publication number: 20020072501
    Abstract: Precursors of adenosine triphosphate are administered orally to increase intracellular ATP concentration as dietary supplements or for treatment of reduced energy availability resulting from strenuous physical activity, illness or trauma. Pentose sugars are administered individually, mixed into dry food or in solution. The preferred pentose is D-ribose, singly or combined with creatine, pyruvate, L-carnitine and/or vasodilating agents. Additionally, magnesium, electrolytes, fatty acids and hexose sugars can be used. The compositions and methods of this invention are especially beneficial to mammals having reduced energy availability or high energy demand.
    Type: Application
    Filed: December 18, 2000
    Publication date: June 13, 2002
    Inventors: John St. Cyr, Clarence A. Johnson
  • Publication number: 20020065232
    Abstract: Persons encountering high altitudes without being acclimatized can prevent or alleviate the symptoms of acute mountain sickness by administration of ribose one to four times a days, beginning immediately on encountering high altitudes and continuing for at least five days.
    Type: Application
    Filed: March 29, 2001
    Publication date: May 30, 2002
    Inventors: Terri L. Butler, John St. Cyr, Clarence A. Johnson
  • Publication number: 20020028196
    Abstract: D-Ribose and methods for using D-Ribose are provided for enhancing the immune response in mammals. Those with a less than optimal immune response will benefit from oral or parenteral administration of D-Ribose. Methods are also provided for the enhancement of the immune response in isolated leukocytes. Leukocytes are cultured ex vivo in the presence of D-Ribose and transfused into a patient in need of leukocyte augmentation.
    Type: Application
    Filed: January 8, 2001
    Publication date: March 7, 2002
    Inventors: Susan S. Percival, Robin J. Henken, John St. Cyr, Clarence A. Johnson, Terri L. Butler
  • Patent number: 6339716
    Abstract: A method of determining the viability of a hibernating or stunned myocardial segment comprises the administration of ribose, a vasodilator and an inotropic agent. The preferred agent is dobutamine, which has both a vasodilation and an inotropic effect. The segments may be identified by myocardial imaging by any known means, such as echocardiography, Thallium-201 tracing or positron emission tomography. Ribose is preferably given one minute to three hours prior to administration of the vasodilator and inotropic agents.
    Type: Grant
    Filed: September 24, 1999
    Date of Patent: January 15, 2002
    Assignee: Bioenergy Inc.
    Inventors: Stephen G. Sawada, John St. Cyr, Clarence A. Johnson
  • Patent number: 6218366
    Abstract: The administration of ribose raises the hypoxic threshold of mammals experiencing a hypoxic condition. The presence of an effective amount of ribose in the tissue of a mammal increases the tolerance to hypoxia and decreases the symptoms of hypoxia in mammals experiencing chronic hypoxia due to cardiovascular disease or peripheral vascular disease. Such mammals are additionally benefited by administration of ribose and a vasodilator or an isotropic agent. Mammals experiencing transient hypoxia from high altitude, anesthesia or exercise are also benefited.
    Type: Grant
    Filed: September 24, 1999
    Date of Patent: April 17, 2001
    Assignee: Bioenergy, Inc.
    Inventors: John St. Cyr, Clarence A. Johnson, Dean J. MacCarter, Stephen G. Sawada
  • Patent number: 6159942
    Abstract: Precursors of adenosine triphosphate are administered orally to increase intracellular ATP concentration as dietary supplements or for treatment of reduced energy availability resulting from strenuous physical activity, illness or trauma. Pentose sugars are administered individually, mixed into dry food or in solution. The preferred pentose is D-ribose, singly or combined with creatine, pyruvate, L-carnitine and/or vasodilating agents. Additionally, magnesium, electrolytes, fatty acids and hexose sugars can be used. The compositions and methods of this invention are especially beneficial to mammals having reduced energy availability or high energy demand.
    Type: Grant
    Filed: April 12, 1999
    Date of Patent: December 12, 2000
    Assignee: Bioenergy, Inc.
    Inventors: John St. Cyr, Clarence A. Johnson
  • Patent number: 4099933
    Abstract: The gasification of coal to produce a methane-rich product gas is accomplished through the controlled slow heating of particulate coal in a gasifier comprising two or more zones, whereby any significant decrease in the density of the coal particles is minimized and particle swelling and friability are significantly reduced, while the carryover of fines and deposition of tars in the product gas conduit are thereby minimized. The particulate coal heating rate in the gasifier zones is usually between about 10.degree. and 200.degree. F per minute. When the particulate coal is to be fed to the gasifier at elevated temperature, further improvements are achieved with swelling type caking coals through their pretreatment by preheating the coal at a slow rate between 10.degree. and 100.degree. F per minute up to about 800.degree. F in multiple fluidized beds.
    Type: Grant
    Filed: June 10, 1975
    Date of Patent: July 11, 1978
    Assignee: Hydrocarbon Research, Inc.
    Inventors: Clarence A. Johnson, John Shen
  • Patent number: 3985516
    Abstract: Low rank coals such as subbituminous or lignites containing more than about 10 wt. % moisture are first dried and then passed to a fluidized bed where the coal is passivated against reabsorption of moisture by coating the warm coal particles with a heavy liquid hydrocarbon material. Such coating substantially prevents the reabsorption of moisture in the coal, and thereby prevents autogenous heating and possible spontaneous ignition during subsequent transportation or storage of the passivated coal.
    Type: Grant
    Filed: August 20, 1975
    Date of Patent: October 12, 1976
    Assignee: Hydrocarbon Research, Inc.
    Inventors: Clarence A. Johnson, William Volk