Patents by Inventor Claribel Luciano-Montalvo

Claribel Luciano-Montalvo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of reducing HIV-replication in human body tissue
    Patent number: 8143231
    Abstract: Mononuclear phagocytes are reservoirs, vehicles of dissemination, and targets for persistent HIV infection. However, not all MP population equally support viral growth. Such differential replication is typified by the greater ability of placental macrophages (PM), as compared to blood borne monocyte-derived macrophages (MDM), to restrict viral replication. A SELDI-TOF protein peak with an m/z of 11,100 identified as cystatin B (CSTB), was significantly lower in uninfected and HIV-infected PM than in MDM. HIV replication can be reduced by down regulating the expression of Cystatin B.
    Type: Grant
    Filed: July 20, 2009
    Date of Patent: March 27, 2012
    Assignee: University of Puerto Rico
    Inventors: Loyda M Melendez, Claribel Luciano-Montalvo