Abstract: The present invention relates to engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention, diagnosis, and/or treatment of disease.

Abstract: A method is disclosed for treating prostate cancer in males by administration of tartrate ions from a tartrate derivative. The tartrate ions in the bloodstream bind to and inhibit prostatic acid phosphatase.

Abstract: A dynamic light scattering analyzer which comprises: a sample cell which comprises a cell housing and a cell chamber, the cell chamber being formed within the cell housing such that the cell chamber is exposed to a membrane which is capable of retaining within the cell chamber the particles of a sample introduced into the cell chamber while allowing a liquid carrier to diffuse across the membrane in and out of the cell chamber; a light source; an optical waveguide which is capable of exposing the particles to a light source and which is capable of receiving the light scattered from the particles within the cell chamber and the light reflected from the waveguide-solution interface; a photodetector which is capable of detecting the light scattered from the particles within the cell chamber and the light reflected from the waveguide-solution interface; and a pump for controlling the flow rate and concentration of the carrier liquid which contacts the membrane.