Abstract: A sample processing module includes a PCR assembly including at least one PCR reaction vial. A sample assembly is configured to hold a fluid sample therein, said sample assembly being attachable to said PCR assembly so as to form a closed system. A delivery channel is formed in said PCR assembly, said delivery channel being in fluidic communication with said PCR reaction vial and with said sample assembly. A pressurization device, said pressurization device being configured to increase a pressure of said fluid sample in said sample assembly and direct at least a portion said fluid sample through said delivery channel to said PCR reaction vial. A chemically inert magnetically responsive bead is disposed within the PCR reaction vial. A system is provided for oscillating for altering a position of the magnetically responsive bead within the PCR reaction vial.

Abstract: A method and apparatus for the mixing of a solution and reagents for various reactions and/or testing having a closed cartridge reaction well, a magnetically responsive bead within the well having a chemically inert coating. A heat source then heats the contents to a target temperature while oscillating magnetic fields move the bead within the well in order to mix the contents and make the contents of the reaction well homogeneous.

Abstract: A method and apparatus for the mixing of a solution and reagents for PCR reactions having a closed cartridge reaction well, a magnetically responsive bead within the well having an optically inert coating and a secondary chemically inert coating. A heat source then heats the contents to a target temperature while oscillating magnetic fields move the bead within the well in order to mix the contents and make the contents of the reaction well homogeneous.