Patents by Inventor Clark C. Chen

Clark C. Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12458800
    Abstract: Systems and methods for treating cancerous tumors (including glioblastoma multiforme (GBM)) with electrotherapy, such as deep brain stimulation (DBS) technology, as disclosed herein. One or more configurations can be generated based on a patients tumor characteristics. The selected configurations can be electrode configurations or settings for an electrical source coupled to the electrodes. The one or more configurations can be targeted for inhibiting cell growth process, such as to inhibit mitosis, immune suppression, or to inhibit DNA replication. Inhibition of cell growth processes can initiate death of the cancerous cells.
    Type: Grant
    Filed: February 20, 2023
    Date of Patent: November 4, 2025
    Assignee: Regents of the University of Minnesota
    Inventors: Clark C. Chen, Gregory Frederick Molnar, Sanjay Dhawan
  • Publication number: 20240209361
    Abstract: This document relates to methods and materials for treating cancer. For example, this document provides nanoparticles (e.g., liposomes and LNPs) encapsulating one or more microRNAs and/or one or more anti-microRNAs. In some cases, nanoparticles (e.g., liposomes and LNPs) encapsulating one or more microRNAs and/or one or more anti-microRNAs can be administered to a mammal (e.g., a human) having cancer to treat the mammal.
    Type: Application
    Filed: April 27, 2022
    Publication date: June 27, 2024
    Inventors: Efrosini Kokkoli, Clark C. Chen, Zachary Schneiderman
  • Publication number: 20230201582
    Abstract: Systems and methods for treating cancerous tumors (including glioblastoma multiforme (GBM)) with electrotherapy, such as deep brain stimulation (DBS) technology, as disclosed herein. One or more configurations can be generated based on a patients tumor characteristics. The selected configurations can be electrode configurations or settings for an electrical source coupled to the electrodes. The one or more configurations can be targeted for inhibiting cell growth process, such as to inhibit mitosis, immune suppression, or to inhibit DNA replication. Inhibition of cell growth processes can initiate death of the cancerous cells.
    Type: Application
    Filed: February 20, 2023
    Publication date: June 29, 2023
    Inventors: Clark C. Chen, Gregory Frederick Molnar
  • Patent number: 11623085
    Abstract: Systems and methods for treating cancerous tumors (including glioblastoma multiforme (GBM)) with electrotherapy, such as deep brain stimulation (DBS) technology, as disclosed herein. One or more configurations can be generated based on a patients tumor characteristics. The selected configurations can be electrode configurations or settings for an electrical source coupled to the electrodes. The one or more configurations can be targeted for inhibiting cell growth process, such as to inhibit mitosis, immune suppression, or to inhibit DNA replication. Inhibition of cell growth processes can initiate death of the cancerous cells.
    Type: Grant
    Filed: August 29, 2019
    Date of Patent: April 11, 2023
    Assignee: Regents of the University of Minnesota
    Inventors: Clark C. Chen, Gregory Frederick Molnar
  • Publication number: 20210346692
    Abstract: Systems and methods for treating cancerous tumors (including glioblastoma multiforme (GBM)) with electrotherapy, such as deep brain stimulation (DBS) technology, as disclosed herein. One or more configurations can be generated based on a patients tumor characteristics. The selected configurations can be electrode configurations or settings for an electrical source coupled to the electrodes. The one or more configurations can be targeted for inhibiting cell growth process, such as to inhibit mitosis, immune suppression, or to inhibit DNA replication. Inhibition of cell growth processes can initiate death of the cancerous cells.
    Type: Application
    Filed: August 29, 2019
    Publication date: November 11, 2021
    Inventors: Clark C. Chen, Gregory Frederick Molnar