Patents by Inventor Clark Distelhorst

Clark Distelhorst has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • INHIBITORS OF BCL-2
    Publication number: 20220143135
    Abstract: Compounds and pharmaceutical compositions thereof for inducing apoptosis in a cell expressing Bcl-2 and IP3R and their use in a method for treating neoplastic disorders in a subject.
    Type: Application
    Filed: January 25, 2022
    Publication date: May 12, 2022
    Inventor: Clark Distelhorst
  • Inhibitors of Bcl-2
    Patent number: 11229641
    Abstract: Compounds and pharmaceutical compositions thereof for inducing apoptosis in a cell expressing Bcl-2 and IP3R and their use in a method for treating neoplastic disorders in a subject.
    Type: Grant
    Filed: February 6, 2017
    Date of Patent: January 25, 2022
    Assignee: CASE WESTERN RESERVE UNIVERSITY
    Inventor: Clark Distelhorst
  • Inhibitors of BCL-2
    Patent number: 10058588
    Abstract: A protease resistant polypeptide includes an amino acid sequence that has a sequence identity at least 80% homologous to about 10 to 80 consecutive amino acids of SEQ ID NO:1.
    Type: Grant
    Filed: May 23, 2017
    Date of Patent: August 28, 2018
    Assignee: Case Western Reserve University
    Inventors: Clark Distelhorst, Yiping Rong
  • INHIBITORS OF BCL-2
    Publication number: 20180161391
    Abstract: A protease resistant polypeptide includes an amino acid sequence that has a sequence identity at least 80% homologous to about 10 to 80 consecutive amino acids of SEQ ID NO:1.
    Type: Application
    Filed: May 23, 2017
    Publication date: June 14, 2018
    Inventors: Clark Distelhorst, Yiping Rong
  • INHIBITORS OF BCL-2
    Publication number: 20170224678
    Abstract: Compounds and pharmaceutical compositions thereof for inducing apoptosis in a cell expressing Bcl-2 and IP3R and their use in a method for treating neoplastic disorders in a subject.
    Type: Application
    Filed: February 6, 2017
    Publication date: August 10, 2017
    Inventor: Clark Distelhorst
  • Inhibitors of Bcl-2
    Patent number: 9657073
    Abstract: A protease resistant polypeptide includes an amino acid sequence that has a sequence identity at least 80% homologous to about 10 to 80 consecutive amino acids of SEQ ID NO:1.
    Type: Grant
    Filed: September 1, 2011
    Date of Patent: May 23, 2017
    Assignee: Case Western Reserve University
    Inventors: Clark Distelhorst, Yiping Rong
  • INHIBITORS OF BCL-2
    Publication number: 20130217633
    Abstract: A protease resistant polypeptide includes an amino acid sequence that has a sequence identity at least 80% homologous to about 10 to 80 consecutive amino acids of SEQ ID NO:1.
    Type: Application
    Filed: September 1, 2011
    Publication date: August 22, 2013
    Applicant: CASE WESTERN RESERVE UNIVERSITY
    Inventors: Clark Distelhorst, Yiping Rong