Patents by Inventor Clark Jeffries

Clark Jeffries has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9422526
    Abstract: The present invention relates to methods of isolating and culturing autologous pluripotent stem (aPS) cells. The present invention also provides isolated aPS cells, populations of aPS cells and cultures of aPS cells. Further provided are culture media for expanding aPS cells and methods of culturing aPS cells. The invention also provides for the use of aPS cells, e.g., for diagnostics, drug evaluation and screening, and regenerative medicine.
    Type: Grant
    Filed: June 14, 2012
    Date of Patent: August 23, 2016
    Assignee: The University of North Carolina at Chapel Hill
    Inventors: Diana Perkins, Clark Jeffries, Vandana Turaga
  • Publication number: 20140220682
    Abstract: The present invention relates to methods of isolating and culturing autologous pluripotent stem (aPS) cells. The present invention also provides isolated aPS cells, populations of aPS cells and cultures of aPS cells. Further provided are culture media for expanding aPS cells and methods of culturing aPS cells. The invention also provides for the use of aPS cells, e.g., for diagnostics, drug evaluation and screening, and regenerative medicine.
    Type: Application
    Filed: June 14, 2012
    Publication date: August 7, 2014
    Applicant: The University of North Carolina at Chapel Hill
    Inventors: Diana Perkins, Clark Jeffries, Vandana Turaga
  • Publication number: 20080098015
    Abstract: A structure and technique for preventing collisions using a hash table in conjunction with a CAM to identify and prevent collisions of binary keys. A portion of the hash value of a binary key, which does not collide with a portion of the hash value of any other reference binary key, is used as an entry in the hash table. If two or more binary keys have identical values of the portions of the hash values, each of these binary keys are stored in their entirety, in the CAM. The key in the CAM provides a pointer to a data structure where the action associated with that binary key is stored. If the binary key is not found in the CAM, the binary key is hashed, and a specific entry in the hash table is selected using a portion of this hash value.
    Type: Application
    Filed: December 21, 2007
    Publication date: April 24, 2008
    Applicant: International Business Machines Corporation
    Inventors: Gordon Davis, Andreas Herkersdorf, Clark Jeffries, Mark Rinaldi
  • Publication number: 20080077979
    Abstract: A remote user, two-way authentication and password change protocol that also allows parties to optionally establish a session key which can be used to protect subsequent communication. In a preferred embodiment, a challenge token is generated and exchanged which is a onetime value that includes a random value that changes from session to session. The construction and use of the challenge token avoids transmission of the password or even the transmission of a digest of the password itself. Thus the challenge token does not reveal any information about a secret password or a digest of the password.
    Type: Application
    Filed: June 14, 2007
    Publication date: March 27, 2008
    Inventors: Clark Jeffries, Mohammad Peyravian
  • Publication number: 20080069113
    Abstract: A method and system for managing asynchronous transfer mode (ATM) traffic in a computer system is disclosed. The computer system is used in sending, receiving, or sending and receiving a plurality of ATM flows. Each ATM flow has a plurality of ATM cells, a minimum ATM bandwidth guarantee, and a maximum ATM bandwidth. The method and system include determining whether excess bandwidth exists for the ATM flows. The method and system also include gracefully increasing a portion of the ATM cells transmitted for each ATM flow during periods of excess bandwidth. The portion of the ATM cells transmitted is not more than the maximum ATM bandwidth limit. If an ATM flow presents a sufficient offered load, the portion of the ATM cells transmitted in the flow is not less than a minimum ATM bandwidth guarantee.
    Type: Application
    Filed: November 28, 2007
    Publication date: March 20, 2008
    Inventors: Patrick Droz, Ilias Iliadis, Clark Jeffries, Andreas Kind, Joseph Logan
  • Publication number: 20080072326
    Abstract: A method of progressive response for invoking and suspending blocking measures that defend against network anomalies such as malicious network traffic so that false positives and false negatives are minimized. When an anomaly is detected, the detector notifies protective equipment such as a firewall or a router to invoke a blocking measure. The blocking measure is maintained for an initial duration, after which it is suspended while another test for the anomaly is made. If the anomaly is no longer evident, the method returns to the state of readiness. Otherwise, a loop is executed to re-applying the blocking measure for a specified duration, then suspend the blocking measure and test again for the anomaly. If the anomaly is detected, the blocking measure is re-applied, and its duration is adapted. If the anomaly is no longer detected, the method returns to the state of readiness.
    Type: Application
    Filed: October 12, 2007
    Publication date: March 20, 2008
    Inventors: Robert Danford, Kenneth Farmer, Clark Jeffries, Robert Sisk, Michael Walter
  • Publication number: 20080061982
    Abstract: System and method for tracking inventory of a multiplicity of products. First RFID tags are associated with respective products or groups of products. Second Active RFID tags are associated with respective first containers for the multiplicity products. A third Active RFID tag is associated with a second container for the first containers. First RFID tags broadcast their respective identifications. Second Active RFID tags hash the identities of the first RFID tags within their respective first containers and broad their hashed values. Third Active RFID tag hash the hashed values broadcast by the second Active RFID tags. An expected value is compared to a result of the third Active RFID tag hashing the hashed values broadcast by the second Active RFID tags.
    Type: Application
    Filed: November 14, 2007
    Publication date: March 13, 2008
    Applicant: INTERNATIONAL BUSINESS MACHINES CORPORATON
    Inventors: Kevin Himberger, Clark Jeffries, Mohammad Peyravian
  • Publication number: 20080031137
    Abstract: Methods and apparatus are provided for metering data packets having a plurality of different packet lengths in a data communications network. A token count TC is incremented at a token increment rate CIR subject to an upper limit CBS on the token count. On arrival of a packet of length L tokens, it is determined if both TC>0 and TC+n?L, where n is a defined number of tokens. If so, the data packet is categorized as in profile and L tokens are subtracted from the token count TC. Otherwise the data packet is categorized out of profile. In some embodiments, n is set to a value in the range 0<n<(Lmax?1) where Lmax is the maximum length of data packets to be metered. In other embodiments, n is varied in the range 0?n?(Lmax?1) in dependence on at least one feedback signal indicating an operational condition in the network. The degree of conformance of the metering system is determined by the parameter n, whereby the conformance level can be tuned to particular multi-length packet environments.
    Type: Application
    Filed: October 10, 2007
    Publication date: February 7, 2008
    Applicant: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventors: Brian Carpenter, Clark Jeffries, Andreas Kind
  • Publication number: 20080028140
    Abstract: A structure and technique for preventing collisions using a hash table in conjunction with a CAM to identify and prevent collision of binary keys. A portion of the hash value of a binary key, which does not collide with a portion of the hash value of any other reference binary key, is used as an entry in the hash table. If two or more binary keys have identical values of the portions of the hash values, each of these binary keys are stored in their entirety, in the CAM. The key in the CAM provides a pointer to a data structure where the action associated with that binary key is stored. If the binary key is not found in the CAM, the binary key is hashed, and a specific entry in the hash table is selected using a portion of this hash value.
    Type: Application
    Filed: October 5, 2007
    Publication date: January 31, 2008
    Applicant: International Business Machines Corporation
    Inventors: Gordon Davis, Andreas Herkersdorf, Clark Jeffries, Mark Rinaldi
  • Publication number: 20070268826
    Abstract: A flow control method and system including an algorithm for deciding to transmit an arriving packet into a processing queue or to discard it, or, in the case of instructions or packets that must not be discarded, a similar method and system for deciding at a service event to transmit an instruction or packet into a processing queue or to skip the service event. The transmit probability is increased or decreased in consideration of minimum and maximum limits for each flow, aggregate limits for sets of flows, relative priority among flows, queue occupancy, and rate of change of queue occupancy. The effects include protection of flows below their minimum rates, correction of flows above their maximum rates, and, for flows between minimum and maximum rates, reduction of constituent flows of an aggregate that is above its aggregate maximum. Practice of the invention results in low queue occupancy during steady congestion.
    Type: Application
    Filed: June 21, 2007
    Publication date: November 22, 2007
    Applicant: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventors: Garesh Balakrishnan, John Chalmers, Clark Jeffries, Jitesh Nair, Larry Nicholson, Ravinder Sabhikhi, Raj Singh
  • Publication number: 20070241905
    Abstract: System and method for recording temperature on an RFID tag. A first RFID tag is attached to a container. The first RFID tag includes a temperature sensor. The container contains a multiplicity of packages. A multiplicity of second RFID tags are attached to the multiplicity of packages, respectively. The first RFID tag transmits temperature information to the multiplicity of second RFID tags. In response, the multiplicity of second RFID tags record the temperature information. Consequently, there is no need for expensive temperature sensors on the multiplicity of RFID tags on the packages. According to features of the present invention, the first RFID tag is an active RFID tag, and the multiplicity of second RFID tags are passive RFID tags. The first RFID tag also transmits other information to the multiplicity of second RFID tags to enable the second RFID tags to authenticate the temperature information.
    Type: Application
    Filed: June 22, 2007
    Publication date: October 18, 2007
    Inventors: Kevin Himberger, Clark Jeffries, Mohammad Peyravian
  • Publication number: 20070164863
    Abstract: System and method for tracking inventory of a multiplicity of products. First RFID tags are associated with respective products or groups of products. Second Active RFID tags are associated with respective first containers for the multiplicity products. A third Active RFID tag is associated with a second container for the first containers. First RFID tags broadcast their respective identifications. Second Active RFID tags hash the identities of the first RFID tags within their respective first containers and broad their hashed values. Third Active RFID tag hash the hashed values broadcast by the second Active RFID tags. An expected value is compared to a result of the third Active RFID tag hashing the hashed values broadcast by the second Active RFID tags.
    Type: Application
    Filed: January 17, 2006
    Publication date: July 19, 2007
    Applicant: International Business Machines Corporation
    Inventors: Kevin Himberger, Clark Jeffries, Mohammad Peyravian
  • Publication number: 20070081456
    Abstract: A method and system for transmitting packets in a packet switching network. Packets received by a packet processor may be prioritized based on the urgency to process them. Packets that are urgent to be processed may be referred to as real-time packets. Packets that are not urgent to be processed may be referred to as non-real-time packets. Real-time packets have a higher priority to be processed than non-real-time packets. A real-time packet may either be discarded or transmitted into a real-time queue based upon its value priority, the minimum and maximum rates for that value priority and the current real-time queue congestion conditions. A non-real-time packet may either be discarded or transmitted into a non-real-time queue based upon its value priority, the minimum and maximum rates for that value priority and the current real-time and non-real-time queue congestion conditions.
    Type: Application
    Filed: December 8, 2006
    Publication date: April 12, 2007
    Inventors: Brahmanand Gorti, Marco Heddes, Clark Jeffries, Andreas Kind, Michael Siegel
  • Publication number: 20070076602
    Abstract: The decision within a packet processing device to transmit a newly arriving packet into a queue to await processing or to discard the same packet is made by a flow control method and system. The flow control is updated with a constant period determined by storage and flow rate limits. The update includes comparing current queue occupancy to thresholds and also comparing present queue occupancy to previous queue occupancy. The outcome of the update is a new transmit probability value. The value is stored for the subsequent period of flow control and packets arriving during that period are subject to a transmit or discard decision that uses that value.
    Type: Application
    Filed: November 15, 2006
    Publication date: April 5, 2007
    Inventors: Clark Jeffries, Jitesh Nair, Michael Siegel, Rama Yedavalli
  • Publication number: 20070058651
    Abstract: The present invention provides for congestion and flow control for a data transmission between computers in a network (e.g., a lossless network) by repeatedly setting a transmission rate for the data transmission at predetermined time intervals. Under the present invention, a ratio of a current occupancy to a maximum occupancy of a queue used for the data transmission is provided (e.g., the ratio can be calculated under the present invention, or obtained as input from an external source). The queue can be that of the receiving computer or of any component (e.g., a switch) that resides in the path of the data transmission. In any event, once the ratio is known, the present invention will set the transmission rate for the data transmission based on a comparison of the ratio to at least one threshold.
    Type: Application
    Filed: August 30, 2005
    Publication date: March 15, 2007
    Applicant: International Business Machines Corporation
    Inventors: Hoyt Bowen, Mircea Gusat, Clark Jeffries
  • Publication number: 20070016456
    Abstract: System, method and program product for reporting status of a process. A flow chart illustrates steps of the process and an order for performance of the steps. Then, a determination is made whether any of the steps has been performed. In response to a determination that any of the steps has been performed, graphically representing on the flow chart that the step has been performed. The graphical representation can be color-coding of the step. The determination that a step has been performed can be made based on user input that the step has been performed, or automatically by a program checking a record indicating that the step has been performed. Also, a program can automatically determine that a deadline for performing one of the steps has passed without performance of the one step. In response, the program initiates a graphical representation on the one step in the flowchart that the deadline has passed without performance of the one step.
    Type: Application
    Filed: July 12, 2005
    Publication date: January 18, 2007
    Applicant: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventors: Kevin Himberger, Clark Jeffries, Allen Roginsky, Charles Lingafelt, Phillip Singleton
  • Publication number: 20070011740
    Abstract: A router includes a relatively low bandwidth communication connection to a small computer, a relatively high bandwidth communication connection to a communication network; and a processing unit for executing in the router a set of permit rules for permitting flow of communication packets with respect to the connections for user initiated sessions, the permit rules including a default rule for discarding all packets with respect to the small computer in traffic not pertaining to sessions initiated by the small computer.
    Type: Application
    Filed: July 7, 2005
    Publication date: January 11, 2007
    Applicant: International Business Machines Corporation
    Inventors: John Davis, Kevin Himberger, Clark Jeffries, Mohammad Peyravian
  • Publication number: 20060261946
    Abstract: System and method for recording temperature on an RFID tag. A first RFID tag is attached to a container. The first RFID tag includes a temperature sensor. The container contains a multiplicity of packages. A multiplicity of second RFID tags are attached to the multiplicity of packages, respectively. The first RFID tag transmits temperature information to the multiplicity of second RFID tags. In response, the multiplicity of second RFID tags record the temperature information. Consequently, there is no need for expensive temperature sensors on the multiplicity of RFID tags on the packages. According to features of the present invention, the first RFID tag is an active RFID tag, and the multiplicity of second RFID tags are passive RFID tags. The first RFID tag also transmits other information to the multiplicity of second RFID tags to enable the second RFID tags to authenticate the temperature information.
    Type: Application
    Filed: May 19, 2005
    Publication date: November 23, 2006
    Applicant: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventors: Kevin David Himberger, Clark Jeffries, Mohammad Peyravian
  • Publication number: 20060265372
    Abstract: A structure and technique for preventing collisions using a hash table in conjunction with a CAM to identify and prevent a collisions of binary keys. A portion of the hash value of a binary key, which does not collide with a portion of the hash value of any other reference binary key, is used as an entry in the hash table. If two or more binary keys have identical values of the portions of the hash values, each of these binary keys are stored in their entirety, in the CAM. The key in the CAM provides a pointer to a data structure where the action associated with that binary key is stored. If the binary key is not found in the CAM, the binary key is hashed, and a specific entry in the hash table is selected using a portion of this hash value.
    Type: Application
    Filed: August 3, 2006
    Publication date: November 23, 2006
    Applicant: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventors: Gordon Davis, Andreas Herkersdorf, Clark Jeffries, Mark Rinaldi
  • Publication number: 20060209898
    Abstract: A codec detects congestion in a packet network and responds via a session control protocol to re-negotiate codec-type and/or parameters with the receiving codec to reduce bit rate for supporting a session. Once the connection and session are established, encoded packets start flowing between the two codecs. A control entity sends and receives network congestion control packets periodically in the session. The congestion control packets provide a “heartbeat” signal to the receiving codec. When the network is not congested, all “heartbeat” packets will be passed through the network. As network congestion increases, routers within the network discard excess packets to prevent network failure. The codecs respond to the missing packets by slowing down the bit rate or proceeding to renegotiate a lower bit rate via the session control protocol. If there are no missing packets, the codecs detect if the session is operating at the highest bit rate, and if not, re-negotiate a higher bit rate.
    Type: Application
    Filed: February 7, 2006
    Publication date: September 21, 2006
    Inventors: Youssef Abdelilah, Gordon Davis, Jeffrey Derby, Dongming Hwang, Clark Jeffries, Malcolm Ware, Hua Ye