Abstract: Devices and methods used to obtain core tissue samples are disclosed. The devices may be configured to drill into cortical bone and saw a hole into a bone lesion and/or bone marrow while obtaining the core tissue sample. The devices can include a motor and a clutch configured to rotate a trocar having a tip configured for drilling and an outer coax cannula having a trephine tip configured for sawing. The core tissue sample may be received within an inner cannula as an intermediate cannula cuts a hole in the bone lesion and/or bone marrow. The devices can include a spacer.

Abstract: A thrombosis macerating and aspiration device for macerating and aspirating blood clots and blockages in a blood vessel is disclosed. In some embodiments, the macerating element of the device rotates and creates a partial vacuum to assist in the aspiration of the blood clot of blockage. The macerating element may have a variety of different designs and shapes and in some embodiments, the macerating element is expandable.

Abstract: A thrombosis macerating device for macerating blood clots and blockages in a blood vessel is disclosed. The macerating device comprises an expandable basket that is rotated to macerate the clot or blockage. The expandable basket is disposed at the distal end of the tubular shaft. The expandable basket comprises a plurality of struts that form a braiding pattern. The braiding pattern of the expandable basket comprises a pick per inch that ranges from 2 to 5.

Abstract: A thrombosis macerating and aspiration device for macerating and aspirating blood clots and blockages in a blood vessel is disclosed. In some embodiments, the macerating element of the device rotates and creates a partial vacuum to assist in the aspiration of the blood clot of blockage. The macerating element may have a variety of different designs and shapes and in some embodiments, the macerating element is expandable.