Patents by Inventor Clary Clish

Clary Clish has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 2-AAA as a Biomarker and Therapeutic Agent for Diabetes
    Publication number: 20160030373
    Abstract: Methods for treating a glucose-related metabolic disorder (e.g., diabetes) comprising administration of 2-aminoadipic acid (2-AAA) to subjects in need thereof. Also described are methods for predicting a subject's risk of developing a glucose-related metabolic disorder, and to methods for selecting and monitoring a treatment for a glucose-related metabolic disorder (e.g., diabetes).
    Type: Application
    Filed: March 10, 2014
    Publication date: February 4, 2016
    Inventors: Robert Gerszten, Thomas Wang, Clary Clish
  • Lipidomic Biomarkers of Diabetes
    Publication number: 20120214821
    Abstract: The invention, in some aspects, relates to methods for predicting a subject's risk of developing a glucose-related metabolic disorder, e.g., diabetes. In some aspects, the invention relates to methods for selecting and monitoring a treatment for a glucose-related metabolic disorder, e.g., diabetes.
    Type: Application
    Filed: January 20, 2012
    Publication date: August 23, 2012
    Applicants: THE BROAD INSTITUTE, INC., THE GENERAL HOSPITAL CORPORATION
    Inventors: Robert Gerszten, Thomas Wang, Eugene Rhee, Clary Clish
  • METHOD FOR TREATING METABOLIC DISEASES
    Publication number: 20100105746
    Abstract: A method for treating a condition of low metabolic rate, dyslipidemia, excess adiposity and/or insulin resistance, or a disease or syndrome characterized by one or more of said conditions in a subject, comprises administering to the subject a therapeutically effective amount of romazarit or a pharmaceutically acceptable salt, ester or prodrug thereof.
    Type: Application
    Filed: July 30, 2009
    Publication date: April 29, 2010
    Inventors: Clary Clish, Shweta Verma, Sanjeev Forsyth, Amanda Souza, Nancy Finkel, Todor Dimitrov, David White
  • METHODS FOR TREATING INFLAMMATION AND RELATED CONDITIONS
    Publication number: 20100069400
    Abstract: A method for treating an inflammatory condition or immune disorder comprises administering to a subject having such a condition or disorder a therapeutically effective amount of at least one compound selected from irindalone, physiologically active enantiomers thereof, and pharmaceutically acceptable salts thereof. The invention further provides a method for elevating levels of anti-inflammatory cytokines such as IL-10 and IL-13 while inhibiting expression of pro-inflammatory cytokines. A pharmaceutical composition, useful for example in topical treatment of psoriasis, comprises a therapeutically effective amount of at least one compound selected from irindalone, physiologically active enantiomers thereof, and pharmaceutically acceptable salts thereof, in a vehicle comprising at least one pharmaceutically acceptable excipient, the vehicle being adapted for topical administration to skin of a subject.
    Type: Application
    Filed: July 10, 2009
    Publication date: March 18, 2010
    Applicant: Ore Pharmaceuticals Inc.
    Inventors: Scott Malstrom, Hellen Mulomi Amuguni, Clary Clish, Amy Anderson Deik, David White
  • Aspirin-triggered lipid mediators
    Publication number: 20070049639
    Abstract: Aspirin triggered lipid mediators (ATLMs) are disclosed which are useful for the treatment of prevention of inflammation associated with various diseases, including ischemia.
    Type: Application
    Filed: January 18, 2006
    Publication date: March 1, 2007
    Inventors: Charles Serhan, Clary Clish