Patents by Inventor Claude Bernard

Claude Bernard has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Low dose IL-2 for treating autoimmune-related or inflammatory disorders
    Patent number: 12491232
    Abstract: The present invention relates to novel therapies for treating autoimmune and inflammatory diseases. More specifically, the present invention relates to a use of low dose interleukin-2 for the treatment of type I diabetes and other autoimmune and/or inflammatory diseases.
    Type: Grant
    Filed: January 6, 2023
    Date of Patent: December 9, 2025
    Assignees: INSERM (Institut National de la Sante et de la Recherche Medicale), Assistance Publique-Hopitaux De Paris, Sorbonne Universite
    Inventors: David Klatzmann, David Saadoun, Patrice Cacoub, Michèle Rosenzwajg, Eliane Piaggio, Gilbert Bensimon, Claude Bernard
  • LOW DOSE IL-2 FOR TREATING AUTOIMMUNE-RELATED OR INFLAMMATORY DISORDERS
    Publication number: 20230149512
    Abstract: The present invention relates to novel therapies for treating autoimmune and inflammatory diseases. More specifically, the present invention relates to a use of low dose interleukin-2 for the treatment of type I diabetes and other autoimmune and/or inflammatory diseases.
    Type: Application
    Filed: January 6, 2023
    Publication date: May 18, 2023
    Applicants: INSERM (Institut National de la Sante et de la Recherche Medicale), Assistance Publique - Hopitaux De Paris, SORBONNE UNIVERSITE
    Inventors: David KLATZMANN, David SAADOUN, Patrice CACOUB, Michèle ROSENZWAJG, Eliane PIAGGIO, Gilbert BENSIMON, Claude BERNARD
  • Use of low dose IL-2 for treating autoimmune-related or inflammatory disorders
    Patent number: 11559566
    Abstract: The present invention relates to novel therapies for treating autoimmune and inflammatory diseases. More specifically, the present invention relates to a use of low dose interleukin-2 for the treatment of type I diabetes and other autoimmune and/or inflammatory diseases.
    Type: Grant
    Filed: July 10, 2020
    Date of Patent: January 24, 2023
    Assignees: INSERM (Institut National de la Sante et de la Recherche Medicale), ASSISTANCE PUBLIQUE HOPITAUX DE PARIS, SORBONNE UNIVERSITE
    Inventors: David Klatzmann, David Saadoun, Patrice Cacoub, Michèle Rosenzwajg, Eliane Piaggio, Gilbert Bensimon, Claude Bernard
  • METHODS OF TREATING OR PREVENTING NEUROLOGICAL DISEASES
    Publication number: 20210169940
    Abstract: The present disclosure provides a method for treating an inflammatory neurological disease comprising administering a population of cells enriched for STRO-1+ cells and/or progeny thereof and/or soluble factors derived therefrom.
    Type: Application
    Filed: February 16, 2021
    Publication date: June 10, 2021
    Applicant: Mesoblast, Inc.
    Inventor: Claude Bernard
  • USE OF LOW DOSE IL-2 FOR TREATING AUTOIMMUNE-RELATED OR INFLAMMATORY
    Publication number: 20210038691
    Abstract: The present invention relates to novel therapies for treating autoimmune and inflammatory diseases. More specifically, the present invention relates to a use of low dose interleukin-2 for the treatment of type I diabetes and other autoimmune and/or inflammatory diseases.
    Type: Application
    Filed: July 10, 2020
    Publication date: February 11, 2021
    Applicants: INSERM (Institut National de la Sante et de la Recherche Medicale), ASSISTANCE PUBLIQUE HOPITAUX DE PARIS, SORBONNE UNIVERSITE
    Inventors: David Klatzmann, David SAADOUN, Patrice CACOUB, Michèle ROSENZWAJG, Eliane PIAGGIO, Gilbert BENSIMON, Claude BERNARD
  • Use of low dose IL-2 for treating autoimmune—related or inflammatory disorders
    Patent number: 10765723
    Abstract: The present invention relates to novel therapies for treating autoimmune and inflammatory diseases. More specifically, the present invention relates to a use of low dose interleukin-2 for the treatment of type I diabetes and other autoimmune and/or inflammatory diseases.
    Type: Grant
    Filed: March 22, 2019
    Date of Patent: September 8, 2020
    Assignees: INSERM (Institut National de la Santé et de la Recherche Médicale, Assistance Publique—Hopitaux De Paris, SORBONNE UNIVERSITE
    Inventors: David Klatzmann, David Saadoun, Patrice Cacoub, Michèle Rosenzwajg, Eliane Piaggio, Gilbert Bensimon, Claude Bernard
  • USE OF LOW DOSE IL-2 FOR TREATING AUTOIMMUNE - RELATED OR INFLAMMATORY DISORDERS
    Publication number: 20190351023
    Abstract: The present invention relates to novel therapies for treating autoimmune and inflammatory diseases. More specifically, the present invention relates to a use of low dose interleukin-2 for the treatment of type I diabetes and other autoimmune and/or inflammatory diseases.
    Type: Application
    Filed: March 22, 2019
    Publication date: November 21, 2019
    Applicants: INSERM (Institut National de la Sante et de la Recherche Medicale), Assistance Publique - Hopitaux De Paris, SORBONNE UNIVERSITE
    Inventors: David Klatzmann, David Saadoun, Patrice Cacoub, Michèle Rosenzwajg, Eliane Piaggio, Gilbert Bensimon, Claude Bernard
  • METHODS OF TREATING OR PREVENTING NEUROLOGICAL DISEASES
    Publication number: 20190201448
    Abstract: The present disclosure provides a method for treating an inflammatory neurological disease comprising administering a population of cells enriched for STRO-1+ cells and/or progeny thereof and/or soluble factors derived therefrom.
    Type: Application
    Filed: January 4, 2019
    Publication date: July 4, 2019
    Applicant: Mesoblast, Inc.
    Inventor: Claude BERNARD
  • Use of low dose IL-2 for treating autoimmune related or inflammatory disorders
    Patent number: 10293028
    Abstract: The present invention relates to novel therapies for treating autoimmune and inflammatory diseases. More specifically, the present invention relates to a use of low dose interleukin-2 for the treatment of type I diabetes and other autoimmune and/or inflammatory diseases.
    Type: Grant
    Filed: May 5, 2017
    Date of Patent: May 21, 2019
    Assignees: INSERM (Institut National de la Santé et de la Recherche Médicale), Assistance Publique—Hopitaux De Paris, SORBONNE UNIVERSITE
    Inventors: David Klatzmann, David Saadoun, Patrice Cacoub, Michéle Rosenzwajg, Eliane Piaggio, Gilbert Bensimon, Claude Bernard
  • Methods of treating multiple sclerosis using STRO-1+ and TNAP+ multipotential cells
    Patent number: 10206951
    Abstract: The present disclosure provides a method for treating an inflammatory neurological disease comprising administering a population of cells enriched for STRO-1+ cells and/or progeny thereof and/or soluble factors derived therefrom.
    Type: Grant
    Filed: June 4, 2012
    Date of Patent: February 19, 2019
    Assignee: MESOBLAST, INC.
    Inventor: Claude Bernard
  • USE OF LOW DOSE IL-2 FOR TREATING AUTOIMMUNE – RELATED OR INFLAMMATORY DISORDERS
    Publication number: 20170304402
    Abstract: The present invention relates to novel therapies for treating autoimmune and inflammatory diseases. More specifically, the present invention relates to a use of low dose interleukin-2 for the treatment of type I diabetes and other autoimmune and/or inflammatory diseases.
    Type: Application
    Filed: May 5, 2017
    Publication date: October 26, 2017
    Applicants: INSERM (Institut National de la Santé et de la Recherche Médicale), Assistance Publique - Hopitaux De Paris, Universite Pierre et Marie Curie (PARIS 6)
    Inventors: David Klatzmann, David Saadoun, Patrice Cacoub, Michèle Rosenzwajg, Eliane Piaggio, Gilbert Bensimon, Claude Bernard
  • Method for stimulating T lymphocytes with IL-2
    Patent number: 9669071
    Abstract: The present invention relates to novel therapies for treating autoimmune and inflammatory diseases. More specifically, the present invention relates to a use of low dose interleukin-2 for the treatment of type I diabetes and other autoimmune and/or inflammatory diseases.
    Type: Grant
    Filed: March 9, 2012
    Date of Patent: June 6, 2017
    Assignees: INSERM (Institut National de la Santé et de la Recherche Médicale), Assistance Publique—Hopitaux De Paris, Universite Pierre et Marie Curie (PARIS 6)
    Inventors: David Klatzmann, David Saadoun, Patrice Cacoub, Michèle Rosenzwajg, Eliane Piaggio, Gilbert Bensimon, Claude Bernard
  • METHODS OF TREATING OR PREVENTING NEUROLOGICAL DISEASES
    Publication number: 20140322276
    Abstract: The present disclosure provides a method for treating an inflammatory neurological disease comprising administering a population of cells enriched for STRO-1+ cells and/or progeny thereof and/or soluble factors derived therefrom.
    Type: Application
    Filed: June 4, 2012
    Publication date: October 30, 2014
    Applicant: MESOBLAST, INC.
    Inventor: Claude Bernard
  • USE OF LOW DOSE IL-2 FOR TREATING AUTOIMMUNE - RELATED OR INFLAMMATORY DISORDERS
    Publication number: 20140004080
    Abstract: The present invention relates to novel therapies for treating autoimmune and inflammatory diseases. More specifically, the present invention relates to a use of low dose interleukin-2 for the treatment of type I diabetes and other autoimmune and/or inflammatory diseases.
    Type: Application
    Filed: March 9, 2012
    Publication date: January 2, 2014
    Inventors: David Klatzmann, David Saadoun, Patrice Cacoub, Michèle Rosenzwajg, Eliane Piaggio, Gilbert Bensimon, Claude Bernard
  • Method and device for electrochemical disinfection of water
    Publication number: 20070000790
    Abstract: The invention relates to a method for electrochemical disinfection of water without addition of chemical products, by means of at least one cell, comprising an anode (1) and a cathode (2), contained in a housing (3), provided with inlet (4) and outlet means (5) for water. Said method is characterised in essentially comprising: a) circulating the water for disinfection in a laminar or quasi-laminar manner, in the space between the catalytic faces opposite the anode (1) and the cathode (2) of a given cell, b) using opposing catalytic faces with identical surfaces, c) supplying electrically each pair of anode and cathode by means of connections (1A) and (2A), arranged in opposition.
    Type: Application
    Filed: February 9, 2004
    Publication date: January 4, 2007
    Inventors: Jose Morales, Claude Bernard, Didier Ginestet, Stephane Morales, Jean-Marie Morales
  • Transparent substrate provided with hydrophobic/oleophobic coating formed by plasma CVD
    Patent number: 6383642
    Abstract: A hydrophobic/oleophobic coating is formed on a substrate by a process, which comprises ionizing at least one precursor during deposition on the substrate, while during deposition the substrate temperature decreases from a temperature above 80° C. to a temperature below 80° C.
    Type: Grant
    Filed: April 10, 2000
    Date of Patent: May 7, 2002
    Assignee: Saint-Gobain Vitrage
    Inventors: David Le Bellac, Claude Bernard
  • Non-plasma CVD method and apparatus of forming Ti1-xA1xN coatings
    Patent number: 6238739
    Abstract: A method for forming a Ti1-xAlxN coating on a part without plasma enhancement, wherein a chemical vapor deposition chamber is heated to 250-500° C.; the part to be coated is heated to 550-650° C. and placed in said chamber; and a mixture of titanium and aluminium chlorides, NH3 and H2 is injected into the chamber. The molar amount of NH3 is greater than the molar amount of chlorides, and the molar amount of hydrogen is over five times greater than the molar amount of chlorides.
    Type: Grant
    Filed: February 2, 1999
    Date of Patent: May 29, 2001
    Assignee: Centre National de la Recherche Scientifique
    Inventors: Roland Madar, Alain Rouault, Elisabeth Blanquet, Claude Bernard, Anne-Marie Dutron
  • Synthesis of W-Si-N films by chemical vapor deposition using WF.sub.6, SiH.sub.4 and NH.sub.3
    Patent number: 5997949
    Abstract: The present invention relates to the forming of amorphous or near-amorphous, ternary films of W-Si-N on substrates by chemical vapor deposition of WF.sub.6, SiH.sub.4 and NH.sub.3 and a carrier gas. The present invention method will allow the conformal forming of amorphous or near-amorphous, ternary films of W-Si-N on patterned non-planar substrates at temperatures at or below about 450.degree. C., by chemical vapor deposition of WF.sub.6, SiH.sub.4 and NH.sub.3 and a carrier gas. A typical temperature range for the formation of the films is between 473.degree. K. and 773.degree. K., while the reactor pressure can be varied between 0.1 to 50 Torr. The composition of the deposited films is adjusted by varying the flow ratios of the reactive gases.
    Type: Grant
    Filed: September 20, 1996
    Date of Patent: December 7, 1999
    Assignees: California Institute of Technology, Sandia Corporation
    Inventors: Marc-A. Nicolet, Roland Madar, Claude Bernard, James G. Fleming, Elizabeth Lynn Roherty-Osmun, Paul M. Smith, Jonathan S. Custer, Ronald V. Jones
  • Chemical vapor deposition of W-Si-N and W-B-N
    Patent number: 5916634
    Abstract: A method of depositing a ternary, refractory based thin film on a substrate by chemical vapor deposition employing precursor sources of tungsten comprising WF.sub.6, either silicon or boron, and nitrogen. The result is a W--Si--N or W--B--N thin film useful for diffusion barrier and micromachining applications.
    Type: Grant
    Filed: October 1, 1996
    Date of Patent: June 29, 1999
    Assignee: Sandia Corporation
    Inventors: James G. Fleming, Elizabeth Lynn Roherty-Osmun, Paul M. Smith, Jonathan S. Custer, Ronald V. Jones, Marc-A. Nicolet, Roland Madar, Claude Bernard
  • Sealing system for the engagement of a container beneath a melting furnace
    Patent number: 5820652
    Abstract: A sealing system for the engagement of a container (24) beneath a melting pot containing a molten material, comprising a shell (30) surrounding a nozzle (40), the nozzle being located in the axis of the neck of the container and permitting the pouring of the material from the melting pot into the container. The shell (30) has tight connection means with the nozzle (40), a base (32) having a bearing surface for the reception of a corresponding bearing surface on the container neck and at least one bellows (33, 34) surrounding the nozzle and connecting the tight connection means to said base, the bellows being able to render the shell retractable along the nozzle axis, means for introducing a gas flow between said bearing surfaces being provided in order to permit the circulation of part of said flow towards the nozzle.
    Type: Grant
    Filed: January 10, 1997
    Date of Patent: October 13, 1998
    Assignee: Compagnie Generale Des Matieres Nucleaires
    Inventors: Claude Bernard, Patrice Roux, Jacques Dollfus, Fran.cedilla.ois Meline