Patents by Inventor Claude C. Grigsby

Claude C. Grigsby has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SELECTIVE CHEMICAL SENSOR
    Publication number: 20240210350
    Abstract: Disclosed is a selective chemical sensor, methods of production, and methods of use, where the sensor utilizes an electrochemical sensor element protected by a semi-selective polymeric matrix in conjunction with a selecting compound doped into the matrix along with an acid or base. The polymeric matrix serves as an analyte capture matrix, while the selecting compound reacts with the analyte, further improving the selectivity of the sensor.
    Type: Application
    Filed: January 26, 2024
    Publication date: June 27, 2024
    Applicant: Government of the United States as Represented by the Secretary of the Air Force
    Inventors: Steve S Kim, Rajesh Naik, Claude C Grigsby, Jennifer A. Martin, Michael Brothers, Yen H Ngo
  • IDENTIFICATION, QUANTITATION AND ANALYSIS OF UNIQUE BIOMARKERS IN SWEAT
    Publication number: 20230165488
    Abstract: A biomarker diagnostic system includes a sensor to collect a sweat sample from a biological subject; a processor operatively connected to the sensor, wherein the processor is configured to perform metabolic and proteomic profiling of biomarkers in the sweat sample. The metabolic and proteomic profile is compared to a predetermined profile of the biomarkers and to determine a physiological status of the biomarkers. The system further includes a feedback unit operatively coupled to the sensor and the processor and configured to output physiological performance data based on the physiological status.
    Type: Application
    Filed: January 9, 2023
    Publication date: June 1, 2023
    Applicant: Government of the United States, as represented by the Secretary of the Air Force
    Inventors: Sean W. Harshman, Anthony V. Qualley, Nicole M. Schaeublin, Jennifer A. Martin, Claude C. Grigsby, Rhonda L. Pitsch
  • Identification, quantitation and analysis of unique biomarkers in sweat
    Patent number: 11547326
    Abstract: A biomarker diagnostic system includes a sensor to collect a sweat sample from a biological subject; a processor operatively connected to the sensor, wherein the processor is configured to perform metabolic and proteomic profiling of biomarkers in the sweat sample. The metabolic and proteomic profile is compared to a predetermined profile of the biomarkers and to determine a physiological status of the biomarkers. The system further includes a feedback unit operatively coupled to the sensor and the processor and configured to output physiological performance data based on the physiological status.
    Type: Grant
    Filed: June 4, 2019
    Date of Patent: January 10, 2023
    Assignee: United States of America as represented by the Secretary of the Air Force
    Inventors: Sean W. Harshman, Anthony V. Qualley, Nicole M. Schaeublin, Jennifer A. Martin, Claude C. Grigsby, Rhonda L. Pitsch
  • Exhaled breath hypoxia biomarkers
    Patent number: 11103159
    Abstract: A method of detecting hypoxia. Detecting hypoxia includes detecting, in exhaled breath, at least one indicator for hypoxia. The at least one indicator is selected from the group consisting of pentanal, 2-pentanone, 2-hexanone, 2-heptanone, 2-cyclopenten-1-one, and 4-butyrolactone.
    Type: Grant
    Filed: February 10, 2017
    Date of Patent: August 31, 2021
    Assignee: United States of America as represented by the Secretary of the Air Force
    Inventors: Sean W. Harshman, Brian A. Geier, Claude C. Grigsby, Jeffrey B. Phillips, Darrin K. Ott
  • IDENTIFICATION, QUANTITATION AND ANALYSIS OF UNIQUE BIOMARKERS IN SWEAT
    Publication number: 20190365298
    Abstract: A biomarker diagnostic system includes a sensor to collect a sweat sample from a biological subject; a processor operatively connected to the sensor, wherein the processor is configured to perform metabolic and proteomic profiling of biomarkers in the sweat sample. The metabolic and proteomic profile is compared to a predetermined profile of the biomarkers and to determine a physiological status of the biomarkers. The system further includes a feedback unit operatively coupled to the sensor and the processor and configured to output physiological performance data based on the physiological status.
    Type: Application
    Filed: June 4, 2019
    Publication date: December 5, 2019
    Applicant: Government of the United States, as represented by the Secretary of the Air Force
    Inventors: Sean W. Harshman, Anthony V. Qualley, Nicole M. Schaeublin, Jennifer A. Martin, Claude C. Grigsby, Rhonda L. Pitsch