Abstract: In a device for interconnecting respective ends of two conduits a male connecting piece (2) is fixed on the end of one of conduits and provided on its outer periphery with annular ridges (4), while a female connecting piece is fixed to the end of the other conduit and comprises, in succession, as viewed from its end opening, a first cylindrical annular portion (5), a convergent frustoconical portion (6) and a divergent frustoconical portion (7) which is connected to a second cylindrical portion. A spherical ring member (10) slidably mounted on male connecting piece (2) engages the cylindrical portion (5) and the convergent frustoconical portion (6) of female connecting piece (3) and is subjected to a longitudinal force, so as to be locked on male connecting piece (2) under the effect of plastic deformation. This device can be used for connecting large diameter pipes used for transporting high pressure fluids, particularly in submarine installations.