Patents by Inventor Claude Gros
Claude Gros has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11529332Abstract: Disclosed is a family of corroles for their use in the treatment of an infection by poxvirus.Type: GrantFiled: November 27, 2018Date of Patent: December 20, 2022Assignees: UNIVERSITE DE BOURGOGNE, NÉOVIRTECH SASInventors: Claude Gros, Franck Gallardo, Nicolas Desbois
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Patent number: 11395816Abstract: Disclosed is a family of corroles for its use in the treatment of an infection by human herpesvirus, especially in the treatment of an infection by human cytomegalovirus.Type: GrantFiled: November 27, 2018Date of Patent: July 26, 2022Assignee: UNIVERSITE DE BOURGOGNEInventors: Claude Gros, Franck Gallardo, Nicolas Desbois
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Publication number: 20210369671Abstract: Disclosed is a family of corroles for its use in the treatment of an infection by human herpesvirus, especially in the treatment of an infection by human cytomegalovirus.Type: ApplicationFiled: November 27, 2018Publication date: December 2, 2021Inventors: Claude GROS, Franck GALLARDO, Nicolas DESBOIS
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Publication number: 20210169853Abstract: Disclosed is a family of corroles for their use in the treatment of an infection by poxvirus.Type: ApplicationFiled: November 27, 2018Publication date: June 10, 2021Inventors: Claude GROS, Franck GALLARDO, Nicolas DESBOIS
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Patent number: 7901948Abstract: The invention relates to the use of molecular tweezers as sensitive materials in chemical sensors intended to detect or assay organic compounds in the vapour state, and in particular nitro compounds. These molecular tweezers correspond to the general formula (I): in which: MC1 and MC2 represent macrocycles; p and q are equal to 0 or 1; X and Y are optionally substituted C1 to C10 alkylene groups; while E represents an optionally substituted cyclic or heterocyclic spacer group; and in which MC1 and MC2 are positioned facing each other. Fields of application: detection of explosives, control and monitoring of atmospheric pollution and of the quality of ambient air in relatively confined spaces, and monitoring of industrial sites.Type: GrantFiled: February 1, 2006Date of Patent: March 8, 2011Assignee: Commissariat A l'Energie AtomiqueInventors: Lionel Hairault, Pierre Montmeat, Eric Pasquinet, Jean-Michel Barbe, Stéphane Brandes, Franck Denat, Claude Gros, Roger Guilard
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Publication number: 20080153168Abstract: The invention relates to the use of molecular tweezers as sensitive materials in chemical sensors intended to detect or assay organic compounds in the vapour state, and in particular nitro compounds. These molecular tweezers correspond to the general formula (I): in which: MC1 and MC2 represent macrocycles; p and q are equal to 0 or 1; X and Y are optionally substituted C1 to C10 alkylene groups; while E represents an optionally substituted cyclic or heterocyclic spacer group; and in which MC1 and MC2 are positioned facing each other. Fields of application: detection of explosives, control and monitoring of atmospheric pollution and of the quality of ambient air in relatively confined spaces, and monitoring of industrial sites.Type: ApplicationFiled: February 1, 2006Publication date: June 26, 2008Applicant: Commissariat a L'Energie AtomiqueInventors: Lionel Hairault, Pierre Montmeat, Eric Pasquinet, Jean-Michel Barbe, Stephane Brandes, Franck Denat, Claude Gros, Roger Guilard
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Patent number: 7094773Abstract: The invention relates to compounds which constitute a class of medicaments which have an anti-inflammatory activity and which act by inhibiting leukotriene A4 (LTA4), and enzyme which is responsible for the biosynthesis of leukotriene LTB4, a major proinflammatory mediator. The invention also relates to therapeutic anti-inflammatory, applications of these compounds as well as for methods of preparing these compounds.Type: GrantFiled: July 28, 2004Date of Patent: August 22, 2006Assignee: Institut National de la Santa et de la rescherche Medicale BioprojetInventors: Denis Danvy, Thierry Monteil, Jean-Christophe Plaquevent, Pierre Duhamel, Lucette Duhamel, Nadine Noel, Claude Gros, Olivier Chamard, Jean-Charles Schwartz, Jeanne-Marie Lecomte, Serge Piettre
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Patent number: 6878723Abstract: The invention concerns compounds inhibiting LTA4 hydrolase of formula (I). The invention also concerns their therapeutic, in particular anti-inflammatory, applications.Type: GrantFiled: April 6, 2000Date of Patent: April 12, 2005Assignees: Institut National de la Sante et de la rescherche Medicale (INSERM), BioprojetInventors: Denis Danvy, Thierry Monteil, Jean-Christophe Plaquevent, Pierre Duhamel, Lucette Duhamel, Nadine Noel, Claude Gros, Olivier Chamard, Jean-Charles Schwartz, Jeanne-Marie Lecomte, Serge Piettre
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Publication number: 20050027013Abstract: The invention relates to compounds which constitute a class of medicaments which have an anti-inflammatory activity and which act by inhibiting leukotriene A4 (LTA4), and enzyme which is responsible for the biosynthesis of leukotriene LTB4, a major proinflammatory mediator. The invention also relates to therapeutic anti-inflammatory, applications of these compounds as well as for methods of preparing these compounds.Type: ApplicationFiled: October 19, 2004Publication date: February 3, 2005Inventors: Denis Danvy, Thierry Monteil, Jean-Christophe Plaquevent, Pierre Duhamel, Lucette Duhamel, Nadine Noel, Claude Gros, Olivier Chamard, Jean-Charles Schwartz, Jeanne-Marie Lecomte, Serge Piettre
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Patent number: 6436973Abstract: The invention concerns LTA4 hydrolase inhibiting compositions of formula (1) as set forth below. It also concerns their therapeutic, in particular anti-inflammatory, applications.Type: GrantFiled: June 11, 2001Date of Patent: August 20, 2002Assignees: Bioprojet, Institut National de la Sante et de la Recherche Medicale (Inserm)Inventors: Denis Danvy, Thierry Monteil, Jean-Christophe Plaquevent, Pierre Duhamel, Lucette Duhamel, Nadine Noel, Claude Gros, Olivier Chamard, Jean-Charles Schwartz, Jeanne-Marie Lecomte
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Patent number: 6013829Abstract: Process for the asymmetric synthesis of S-acyl derivatives of 2-mercaptomethyl-3-phenylpropanoic acid of formula (I): characterized in that it comprises the steps consisting in:a) preparing the diol (VI) by reduction of a malonic ester (V) in the presence of a hydride;b) preparing the monoacetates (VII R) or (VII S) respectively;c) subjecting these monoacetates to an oxidation in order to form the acids (IX S) or (IX R);d) saponifying the compounds (IX S) or (IX R) in order to form the hydroxy acids (X S) or (X R);e) thioacylating the hydroxy acids (X S) or (X R) with a mercapto acid R.sub.1 SH (XI), according to a Mitsunobu-type reaction, in order to lead to the desired acids (I R) (I S) respectively and application to the synthesis of N-(mercaptoacyl)amino acid derivatives (II).Type: GrantFiled: November 26, 1997Date of Patent: January 11, 2000Assignee: Societe Civile BioprojetInventors: Denis Danvy, Thierry Monteil, Pierre Duhamel, Lucette Duhamel, Jeanne-Marie Lecomte, Jean-Charles Schwartz, Nadine Noel-Lefebvre, Claude Gros, Jean-Christophe Plaquevent
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Patent number: 5670531Abstract: Amino acid derivatives having both enkephalinase and ACE inhibiting properties corresponding to the formula: ##STR1##Type: GrantFiled: June 5, 1995Date of Patent: September 23, 1997Assignee: Societe Civile BioprojetInventors: Jean-Christophe Plaquevent, Denis Danvy, Thierry Monteil, Helene Greciet, Lucette Duhamel, Pierre Duhamel, Claude Gros, Jean-Charles Schwartz, Jeanne-Marie Lecomte
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Patent number: 5646313Abstract: New amino acid derivatives, processes for their preparation, and their therapeutic application are described.These amino acid derivatives correspond to the general formulae ##STR1## These derivatives may be used as medicaments which exhibit an enkephalinase-inhibitory activity.Type: GrantFiled: June 5, 1995Date of Patent: July 8, 1997Assignee: Societe Civile BioprojetInventors: Denis Danvy, Thierry Monteil, Christophe Lusson, Jean-Charles Schwartz, Claude Gros, Nadine Noel, Jeanne-Marie LeComte, Pierre Duhamel, Lucette Duhamel
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Patent number: 5612371Abstract: New amino acid derivatives, processes for their preparation and their therapeutic application.Amino acid derivatives corresponding to the general formulae ##STR1## These derivatives may be used as medicaments which exhibit an enkephalinase-inhibitory activity.Type: GrantFiled: July 18, 1994Date of Patent: March 18, 1997Assignee: Societe Civile BioprojectInventors: Denis Danvy, Thierry Monteil, Christophe Lusson, Jean-Charles Schwartz, Claude Gros, Nadine Noel, Jeanne-Marie Lecomte, Pierre Duhamel, Lucette Duhamel
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Patent number: 5599951Abstract: Amino acid derivatives of formula (Ia) and (Ib) and prodrugs thereof containing a group responsible for chelating the zinc atom of enkephalinase and angiotensin convertase enzymes are disclosed as inhibitors of these enzymes.Type: GrantFiled: April 14, 1995Date of Patent: February 4, 1997Assignee: Societe Civile BioprojetInventors: Jean-Christophe Plaquevent, Denis Danvy, Thierry Monteil, Claude Gros, Jean-Charles Schwartz, Jeanne-Marie LeComte, Helene Greciet, Lucette Duhamel, Pierre Duhamel
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Patent number: 5331008Abstract: The (R) or (S) isomer of acetorphan or N-/(acetylthiomethyl)-2-oxo-1-phenyl-3-propyl/(S) alanine methyl ester is prepared by splitting of racemic acetylthio-3-benzyl-2-propanoic acid by reaction with ephedrin, separation of the enantiomeric salt obtained, then freeing of the acid and coupling with the corresponding amino acid ester. The obtained preparations possess remarkable therapeutic activities and can notably be used as drugs.Type: GrantFiled: February 1, 1993Date of Patent: July 19, 1994Assignee: Societe Civile BioprojetInventors: Pierre Duhamel, Lucette Duhamel, Denis Danvy, Jean-Christophe Plaquevent, Bruno Giros, Claude Gros, Jean-Charles Schwartz, Jeanne-Marie Lecomte
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Patent number: 5296509Abstract: The (R) or (S) isomer of acetorphan or N-/(acetylthiomethyl)-2-oxo-1-phenyl-3-propyl/(S) alanine methyl ester is prepared by splitting of racemic acetylthio-3-benzyl-2-propanoic acid by reaction with ephedrin, separation of the enantiomeric salt obtained, then freeing of the acid and coupling with the corresponding amino acid ester. The obtained preparations possess remarkable therapeutic activities and can notably be used as drugs.Type: GrantFiled: February 1, 1993Date of Patent: March 22, 1994Assignee: Societe Civile BioprojetInventors: Pierre Duhamel, Lucette Duhamel, Denis Danvy, Jean-Christophe Plaquevent, Bruno Giros, Claude Gros, Jean-Charles Schwartz, Jeanne-Marie Lecomte
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Patent number: 5208255Abstract: The (R) or (S) isomer of acetorphan or N-/2-acetylthiomethyl)-1-oxo-3-phenylpropyl/(S) alanine methyl ester is prepared by splitting of racemic acetylthio-2-benzylpropanoic acid by reaction with ephedrin, separation of the enantiomeric salt obtained, then freeing of the acid and coupling with the corresponding amino acid ester. The obtained preparations possess remarkable therapeutic activities and can notably be used as drugs.Type: GrantFiled: November 22, 1988Date of Patent: May 4, 1993Assignee: Societe Civile BioprojetInventors: Pierre Duhamel, Lucette Duhamel, Denis Danvy, Jean-Christophe Plaquevent, Bruno Giros, Claude Gros, Jean-Charles Schwartz, Jeanne-Marie Lecomte
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Patent number: 5136076Abstract: The (R) or (S) isomer of acetorphan or N-12-acetylthiomethyl-1-oxo-3-phenyl propyl/(S) alanine methyl ester is prepared by splitting of racemic 3-acetylthio-2-benzyl propanoic acid by reaction with ephedrin, separation of the enantiomeric salt obtained, then freeing of the acid and coupling with the corresponding amino acid ester. The obtained preparations possess remarkable therapeutic activities and can notably be used as drugs.Type: GrantFiled: June 19, 1990Date of Patent: August 4, 1992Assignee: Societe Civile BioprojetInventors: Pierre Duhamel, Lucette Duhamel, Denis Danvy, Jean-Christophe Plaquevent, Bruno Giros, Claude Gros, Jean-Charles Schwartz, Jeanne-Marie Lecomte