Patents by Inventor Claude Lardy

Claude Lardy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8357721
    Abstract: The invention relates to compounds of the general formula (I) wherein R1, R2, R3, R4, R5, R6, i and j have the meanings given in claim 1, and to the use thereof as caspase-10 inhibitors, especially for the treatment of diabetic retinopathy.
    Type: Grant
    Filed: April 6, 2006
    Date of Patent: January 22, 2013
    Assignee: Merck Patent GmbH
    Inventors: Claude Lardy, Marc Lecomte, Thierry Convard, Catherine Vidal
  • Patent number: 7829721
    Abstract: The invention relates to compounds of the general formula (I), and to their use as caspase-10 inhibitors, especially for the treatment of diabetic retinopathy.
    Type: Grant
    Filed: November 2, 2005
    Date of Patent: November 9, 2010
    Assignee: Merck Patent GmbH
    Inventors: Claude Lardy, Marc Lecomte, Catherine Vidal, Thierry Convard, Stéphane Yvon, Marie Noelle Denuault, Denis Descours
  • Publication number: 20080255173
    Abstract: The invention relates to compounds of the general formula (I), and to their use as caspase-10 inhibitors, especially for the treatment of diabetic retinopathy.
    Type: Application
    Filed: November 2, 2005
    Publication date: October 16, 2008
    Inventors: Claude Lardy, Marc Lecomte, Catherine Vidal, Thierry Convard, Stephane Yvon, Marie Noelle Denuault, Denis Descours
  • Publication number: 20080182906
    Abstract: The invention relates to compounds of the general formula (I) wherein R1, R2, R3, R4, R5, R6, i and j have the meanings given in claim 1, and to the use thereof as caspase-10 inhibitors, especially for the treatment of diabetic retinopathy.
    Type: Application
    Filed: April 6, 2006
    Publication date: July 31, 2008
    Inventors: Claude Lardy, Marc Lecomte, Thierry Convard, Catherine Vidal
  • Publication number: 20070129433
    Abstract: The invention relates to compounds of the formula (I) in which: i and j=1; R1 is in position 3 or 4 on the phenyl ring and represents a cyano group, an alkoxy group substituted by halogen, a thioalkyl group, an alkylcarbonyl group or an alkylsulfonyl group; and R2 represents a carboxyl group, an aikoxycarbonyl group, an alkylcarbonyl group, an unsubstituted amide group or a linear or branched alkyl group substituted by a cyano, hydroxyl, cabboxyl, aikoxycarbonyl or unsubstituted amide group; and also the pharmaceutically acceptable derivatives, salts, solvates and stereoisomers thereof, including mixtures thereof in all proportions.
    Type: Application
    Filed: November 17, 2004
    Publication date: June 7, 2007
    Inventors: Claude Lardy, Philippe Guedat, Lidia Caputo
  • Publication number: 20070123586
    Abstract: The invention relates to a compound of the formula I in which: R1 represents, independently of each other, a halogen atom; an aliphatic hydrocarbon-based group optionally substituted and/or optionally interrupted by one or more oxygen or sulfur atoms; a nitro group; a cyano group; an amino group; a mono- or dialkylamino group; an alkylcarbonyl group; a carboxyl group; an alkylcarbonylamino group; an alkylsulfonyl group; R2 represents, independently of each other, a cyano group; a hydroxyl group, an alkylcarbonyl group; a carboxyl group; an alkoxycarbonyl group; an unsubstituted amide group; or a linear or branched alkyl group substituted by a cyano, hydroxyl, carboxyl, alkoxycarbonyl or unsubstituted amide group; i and j independently being 1 to 5, with the exclusion of the compound for which i and j=1 and R1=carboxyl and R2=alkoxycarbonyl or R1=CF3 and R2=carboxyl, and also the pharmaceutically acceptable derivatives, salts, solvates and stereoisomers thereof, including mixtures thereof in all propo
    Type: Application
    Filed: November 17, 2004
    Publication date: May 31, 2007
    Inventors: Claude Lardy, Phillippe Guedat, Lidia Caputo
  • Publication number: 20070072915
    Abstract: The present invention relates to novel phenoxyacetamide derivatives, to a process for the preparation thereof and to the use thereof for the preparation of diphenylamines.
    Type: Application
    Filed: November 5, 2004
    Publication date: March 29, 2007
    Inventors: Claude Lardy, Bernard Boudet
  • Publication number: 20060052588
    Abstract: The present invention relates to a novel nitrosation polymer of the formula in which X, Y, R1, R2 and R3 are as defined in claim 1. The invention also relates to a process for the preparation of the said polymer.
    Type: Application
    Filed: September 6, 2003
    Publication date: March 9, 2006
    Inventors: Didier Roche, Claude Lardy
  • Publication number: 20050154232
    Abstract: Compounds of formula (I) in which each of the phenyl rings represented is optionally substituted one or more times; n represents an integer selected from 0, 1, Z, 3, 4 and 5; W represents —CO— or —SO—2; Z represents H; alkyl; aryl; or arylalkyl R1 represents any monovalent organic group; and the pharmaceutically acceptable salts thereof, can be used in the treatment of pathologies that are characterized by an oxidative stress condition.
    Type: Application
    Filed: February 12, 2003
    Publication date: July 14, 2005
    Inventors: Claude Lardy, Didier Festal, Lidia Caputo, Daniel Guerrier
  • Publication number: 20040063783
    Abstract: The present invention relates to a compound of formula (I) in which X, A, T, Y, G and R are as defined in Claim (1).
    Type: Application
    Filed: April 3, 2003
    Publication date: April 1, 2004
    Inventors: Claude Lardy, Jean-Yves Nioche, Lidia Caputo, Jacques Decerprit, Jean-Yves Ortholand, Didier Festal, Daniel Guerrier
  • Publication number: 20030203966
    Abstract: The invention concerns novel compounds of general formula (1), their tautomeric forms, and their additive salts with pharmaceutically acceptable bases. The invention also concerns methods for preparing these compounds and their applications as medicines. These compounds inhibit the aldose reductase enzyme and can be used in the treatment or prevention of peripheral and autonomous neurological diabetic complications, renal and ocular disorders such as cataract and retinopathy.
    Type: Application
    Filed: November 12, 2002
    Publication date: October 30, 2003
    Inventors: Francois Collonges, Herve Dumas, Claude Lardy, Philippe Durbin
  • Publication number: 20030171422
    Abstract: The present invention relates to the compounds of formula: 1
    Type: Application
    Filed: February 12, 2003
    Publication date: September 11, 2003
    Applicant: Merck Patent GmbH
    Inventors: Claude Lardy, Jaques Barbanton, Herve Dumas, Francois Collonges, Phillppe Durbin
  • Patent number: 6559185
    Abstract: The present invention relates to the compounds of formula: in which R1, R2, R3, E, A, X, Z, p and n are as defined herein. These compounds are aldose reductase inhibitors.
    Type: Grant
    Filed: November 12, 1999
    Date of Patent: May 6, 2003
    Assignee: Merck Patent GmbH
    Inventors: Claude Lardy, Jaques Barbanton, Herve Dumas, Francois Collonges, Philippe Durbin
  • Publication number: 20030069312
    Abstract: The present invention relates to the compounds of formula: 1
    Type: Application
    Filed: November 12, 1999
    Publication date: April 10, 2003
    Inventors: CLAUDE LARDY, JAQUES BARBANTON, HERVE DUMAS, FRANCOIS COLLONGES, PHILLIPE DURBIN
  • Patent number: 6509499
    Abstract: The invention concerns novel compound of general formula (1) in which: P, T1, T2, X and n are as defined in claim 1, their tautomeric forms, and their additive salts with pharmaceutically acceptable bases. The invention also concerns methods for preparing these compounds and their applications as medicines. These compounds inhibit the aldose reductase enzyme and can be used in the treatment or prevention of peripheral and autonomous neurological diabetic complications, renal and ocular disorders such as cataract and retinopathy.
    Type: Grant
    Filed: March 17, 2000
    Date of Patent: January 21, 2003
    Assignee: Merck PatentGesellschaft mit
    Inventors: François Collonges, Hervé Dumas, Claude Lardy, Philippe Durbin
  • Patent number: 6043281
    Abstract: The present invention relates to the compounds of formula: ##STR1## in which R.sub.1, R.sub.2, R.sub.3, E, A, X, Z, p and n are as defined herein. These compounds are aldose reductase inhibitors.
    Type: Grant
    Filed: February 25, 1999
    Date of Patent: March 28, 2000
    Assignee: Merck Patent Gesellschaft mit Beschrankter Haftung
    Inventors: Claude Lardy, Jaques Barbanton, Herve Dumas, Francois Collonges, Philippe Durbin
  • Patent number: 5932765
    Abstract: The present invention relates to the compounds of formula: ##STR1## in which R.sub.1, R.sub.2, R.sub.3, E, A, X, Z, p and n are as defined herein. These compounds are aldose reductase inhibitors.
    Type: Grant
    Filed: October 22, 1997
    Date of Patent: August 3, 1999
    Assignee: Merck Patent Gesellschaft Mit
    Inventors: Claude Lardy, Jaques Barbanton, Herve Dumas, Francois Collonges, Phillippe Durbin
  • Patent number: 5476846
    Abstract: The present invention concerns new substituted sulfonamides, and the physiologically acceptable salts, complexes, esters and amides thereof, represented by the formula ##STR1## which is defined herein. Said compounds find application as anti-thrombotic and anti-asthmatic medicines.
    Type: Grant
    Filed: November 17, 1994
    Date of Patent: December 19, 1995
    Assignee: Lipha, Lyonnaise Industrielle Pharmaceutique
    Inventors: Claude Lardy, Daniel Guerrier, Gilles Chavernac, Francois Collonges
  • Patent number: 5387709
    Abstract: The present invention concerns new substituted sulfonamides, and the physiologically acceptable salts possibly in the form of complexes, esters and amides thereof, represented by the formula: ##STR1##
    Type: Grant
    Filed: October 12, 1993
    Date of Patent: February 7, 1995
    Assignee: Lipha Lyonnaise Industrielle Pharmaceutique
    Inventors: Claude Lardy, Daniel Guerrier, Gilles Chavernac, Francois Collonges