Abstract: A cart handle cover system includes a roll of cart handle covers contained within a dispenser for dispensing the covers from the roll. One or more rolls of covers are rotatingly positioned about a roll support rod inside the dispenser. The dispenser includes a dispensing slot near the top on one side of the dispenser. When the roll of covers is advanced through the dispensing slot, a user can peel one of the covers from the roll for application to a cart handle. Accordingly, a sanitary barrier for protecting customers' hands from potential contaminants on a shopping cart handle can be conveniently provided to customers in a retail store.