Patents by Inventor Claudia Betschart

Claudia Betschart has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Disubstituted heteroaryl-fused pyridines
    Patent number: 8742106
    Abstract: The invention relates to compound of the formula (I?) in which the substituents are as defined in the specification; in free form or in salt form; to its preparation, to its use as medicament and to medicaments comprising it.
    Type: Grant
    Filed: December 20, 2010
    Date of Patent: June 3, 2014
    Assignee: Novartis AG
    Inventors: Sangamesh Badiger, Dirk Behnke, Claudia Betschart, Vinod Chaudhari, Murali Chebrolu, Simona Cotesta, Samuel Hintermann, Arndt Meyer, Chetan Pandit
  • DIAZA-SPIRO[5.5]UNDECANES USEFUL AS OREXIN RECEPTOR ANTAGONISTS
    Publication number: 20130281463
    Abstract: The invention relates to compound of the formula (I), in which the substituents are as defined in the specification; in free form or in salt form; to its preparation, to its use as medicament and to medicaments comprising it.
    Type: Application
    Filed: October 25, 2011
    Publication date: October 24, 2013
    Applicant: NOVARTIS AG
    Inventors: Sangamesh Badiger, Dirk Behnke, Claudia Betschart, Simona Cotesta, Samuel Hintermann, Silvio Ofner, Chetan Pandit, Bernard Lucien Roy
  • Diaza-spiro[5.5]undecanes
    Patent number: 8530648
    Abstract: The invention relates to compound of the formula (I), in which the substituents are as defined in the specification; in free form or in salt form; to its preparation, to its use as medicament and to medicaments comprising it.
    Type: Grant
    Filed: December 20, 2010
    Date of Patent: September 10, 2013
    Assignee: Novartis AG
    Inventors: Sangamesh Badiger, Dirk Behnke, Claudia Betschart, Vinod Chaudhari, Simona Cotesta, Jürgen Hans-Hermann Hinrichs, Silvio Ofner, Chetan Pandit, Jürgen Wagner
  • DIAZA-SPIRO[5.5]UNDECANES
    Publication number: 20120264748
    Abstract: The invention relates to compound of the formula (I), in which the substituents are as defined in the specification; in free form or in salt form; to its preparation, to its use as medicament and to medicaments comprising it.
    Type: Application
    Filed: December 20, 2010
    Publication date: October 18, 2012
    Applicant: NOVARTIS AG
    Inventors: Sangamesh Badiger, Dirk Behnke, Claudia Betschart, Vinod Chaudhari, Simona Cotesta, Jürgen Hans-Hermann Hinrichs, Silvio Ofner, Chetan Pandit, Jürgen Wagner
  • DISUBSTITUTED HETEROARYL-FUSED PYRIDINES
    Publication number: 20120258973
    Abstract: The invention relates to compound of the formula (I?) in which the substituents are as defined in the specification; in free form or in salt form; to its preparation, to its use as medicament and to medicaments comprising it.
    Type: Application
    Filed: December 20, 2010
    Publication date: October 11, 2012
    Applicant: NOVARTIS AG
    Inventors: Sangamesh Babiger, Dirk Behnke, Claudia Betschart, Vinod Chaudhari, Murali Chebrolu, Simona Cotesta, Samuel Hintermann, Arndt Meyer, Chetan Pandit
  • Di/tri-aza-spiro-C9-C11alkanes
    Publication number: 20120165331
    Abstract: The invention relates to compounds of the formula I A-D-C(R1)2—B??(I), in which the substituents are as defined in the specification; in free form or in salt form; to its preparation, to its use as medicament and to medicaments comprising it.
    Type: Application
    Filed: December 19, 2011
    Publication date: June 28, 2012
    Inventors: Sangamesh BADIGER, Dirk BEHNKE, Claudia BETSCHART, Vinod CHAUDHARI, Simona COTESTA, Samuel HINTERMANN, Andreas LERCHNER, Fatma LIMAM, Silvio OFNER, Chetan PANDIT, Jürgen WAGNER
  • Diaza-spiro[5.5]undecanes
    Publication number: 20120101110
    Abstract: The invention relates to compound of the formula I in which the substituents are as defined in the specification; in free form or in salt form; to its preparation, to its use as medicament and to medicaments comprising it.
    Type: Application
    Filed: October 18, 2011
    Publication date: April 26, 2012
    Inventors: Sangamesh BADIGER, Dirk BEHNKE, Claudia BETSCHART, Simona COTESTA, Samuel HINTERMANN, Silvio OFNER, Chetan PANDIT, Bernard Lucien ROY
  • Macrocyclic compounds useful as BACE inhibitors
    Patent number: 8039455
    Abstract: The invention relates to novel macrocyclic compounds of the formula in which all of the variables are as defined in the specification, in free base form or in acid addition salt form, to their preparation, to their use as medicaments and to medicaments comprising them.
    Type: Grant
    Filed: December 28, 2006
    Date of Patent: October 18, 2011
    Assignee: Novartis AG
    Inventors: Claudia Betschart, Manuel Koller, Kurt Laumen, Andreas Lerchner, Rainer Machauer, Clive McCarthy, Marina Tintelnot-Blomley, Siem Jacob Veenstra
  • Heteroaryl nitrile derivatives
    Patent number: 7820818
    Abstract: The invention provides compounds of formula I or a pharmaceutically acceptable salt or ester thereof wherein the symbols have meaning as defined, which are inhibitors of cathepsin K and find use pharmaceutically for treatment of diseases and medical conditions in which cathepsin K is implicated, e.g. various disorders including inflammation, rheumatoid arthritis, osteoarthritis, osteoporosis and tumors.
    Type: Grant
    Filed: March 6, 2009
    Date of Patent: October 26, 2010
    Assignee: Novartis AG
    Inventors: Eva Altmann, Claudia Betschart, Kenji Hayakawa, Osamu Irie, Junichi Sakaki, Genji Iwasaki, Rene Lattmann, Martin Missbach, Naoki Teno
  • 4-ARYL-BUTANE-1,3-DIAMIDES
    Publication number: 20100222396
    Abstract: The invention relates to compound of the formula I in which the substituents are as defined in the specification; in free form or in salt form; to its preparation, to its use as medicament and to medicaments comprising it.
    Type: Application
    Filed: January 28, 2010
    Publication date: September 2, 2010
    Applicant: Novartis AG
    Inventors: Dirk BEHNKE, Claudia Betschart, Simona Cotesta, Marc Gerspacher, Samuel Hintermann, Bernard Lucien Roy, Anette Von Matt, Jürgen Wagner
  • Macrocyclic Lactams and Pharmaceutical Use Thereof
    Publication number: 20100022500
    Abstract: The present invention relates to novel macrocyclic compounds of the formula wherein R1, R2, R3, U, V, W, X, Y, Z and n are as defined in the specification, the number of ring atoms included in the macrocyclic ring being 14, 15, 16 or 17, in free base form or in acid addition salt form, to their preparation, to their use as pharmaceuticals and to pharmaceutical compositions comprising them.
    Type: Application
    Filed: September 25, 2009
    Publication date: January 28, 2010
    Inventors: Yves AUBERSON, Claudia Betschart, Ralf Glatthar, Kurt Laumen, Rainer MacHauer, Marina Tintelnot-Blomley, Thomas J. Troxler, Siem Jacob Veenstra
  • Macrocyclic lactams and pharmaceutical use thereof
    Patent number: 7612055
    Abstract: The present invention relates to novel macrocyclic compounds of the formula wherein R1, R2, R3, U, V, W, X, Y, Z and n are as defined in the specification, the number of ring atoms included in the macrocyclic ring being 14, 15, 16 or 17, in free base form or in acid addition salt form, to their preparation, to their use as pharmaceuticals and to pharmaceutical compositions comprising them.
    Type: Grant
    Filed: November 4, 2004
    Date of Patent: November 3, 2009
    Assignee: Novartis AG
    Inventors: Yves Auberson, Claudia Betschart, Ralf Glatthar, Kurt Laumen, Rainer Machauer, Marina Tintelnot-Blomley, Thomas J. Troxler, Siem Jacob Veenstra
  • Dibenzo[b,f]oxepine-10-carboxamides and pharmaceutical uses thereof
    Patent number: 7612054
    Abstract: The present invention pertains to novel dibenzo[b,f]oxepine-10-carboxamides compound to a process for the preparation of such compounds of formula I, their use as a pharmaceuticals, especially in the treatment of neurological and vascular disorders related to beta-amyloid generation and/or aggregation, and to pharmaceutical compositions and combinations comprising such compounds of formula I.
    Type: Grant
    Filed: July 23, 2004
    Date of Patent: November 3, 2009
    Assignee: Novartis AG
    Inventors: Yves Auberson, Claudia Betschart, Stefanie Flohr, Ralf Glatthar, Oliver Simic, Marina Tintelnot-Blomley, Thomas J. Troxler, Eric Vangrevelinghe, Siem Jacob Veenstra
  • HETEROARYL NITRILE DERIVATIVES
    Publication number: 20090227596
    Abstract: The invention provides compounds of formula I or a pharmaceutically acceptable salt or ester thereof wherein the symbols have meaning as defined, which are inhibitors of cathepsin K and find use pharmaceutically for treatment of diseases and medical conditions in which cathepsin K is implicated, e.g. various disorders including inflammation, rheumatoid arthritis, osteoarthritis, osteoporosis and tumors.
    Type: Application
    Filed: March 6, 2009
    Publication date: September 10, 2009
    Inventors: Eva Altmann, Claudia Betschart, Kenji Hayakawa, Osamu Irie, Junichi Sakaki, Genji Iwasaki, Rene Lattmann, Martin Missbach, Naoki Teno
  • Hetereoaryl nitrile derivatives
    Patent number: 7544688
    Abstract: The invention provides compounds of Formula (I) or a pharmaceutically acceptable salt or ester thereof wherein the symbols have meaning as defined, which are inhibitors of cathepsin K and find use pharmaceutically for treatment of diseases and medical conditions in which cathepsin K is implicated, e.g. various disorders including inflammation, rheumatoid arthritis, osteoarthritis, osteoporosis and tumors.
    Type: Grant
    Filed: August 29, 2003
    Date of Patent: June 9, 2009
    Assignee: Novartis AG
    Inventors: Eva Altmann, Claudia Betschart, Kenji Hayakawa, Osamu Irie, Junichi Sakaki, Genji Iwasaki, Rene Lattmann, Martin Missbach, Naoki Teno
  • Pyrrolo Pyrimidines as Agents for the Inhibition of Cystein Proteases
    Publication number: 20090054467
    Abstract: The invention provides compounds of Formula I or a pharmaceutically acceptable salt or ester thereof wherein the symbols have meaning as defined, which are inhibitors of cathepsin K and find use pharmaceutically for treatment of diseases and medical conditions in which cathepsin K is implicated, e.g. various disorders including inflammation, rheumatoid arthritis, osteoarthritis, osteoporosis and tumors.
    Type: Application
    Filed: September 25, 2008
    Publication date: February 26, 2009
    Inventors: Claudia Betschart, Kenji Hayakawa, Osamu Irie, Junichi Sakaki, Genji Iwasaki, Rene Lattmann, Martin Missbach, Naoki Teno
  • MACROCYCLIC COMPOUNDS USEFUL AS BASE INHIBITORS
    Publication number: 20090029960
    Abstract: The invention relates to novel macrocyclic compounds of the formula in which all of the variables are as defined in the specification, in free base form or in acid addition salt form, to their preparation, to their use as medicaments and to medicaments comprising them.
    Type: Application
    Filed: December 28, 2006
    Publication date: January 29, 2009
    Inventors: Claudia Betschart, Manuel Koller, Kurt Laumen, Andreas Lerchner, Rainer Machauer, Clive McCarthy, Marina Tintelnot-Blomley, Siem Jacob Veenstra
  • Pyrrolo pyrimidines as agents for the inhibition of cystein proteases
    Patent number: 7452886
    Abstract: The invention provides compounds of Formula I or a pharmaceutically acceptable salt or ester thereof wherein the symbols have meaning as defined, which are inhibitors of cathepsin K and find use pharmaceutically for treatment of diseases and medical conditions in which cathepsin K is implicated, e.g. various disorders including inflammation, rheumatoid arthritis, osteoarthritis, osteoporosis and tumors.
    Type: Grant
    Filed: August 29, 2002
    Date of Patent: November 18, 2008
    Assignee: Novartis AG
    Inventors: Claudia Betschart, Kenji Hayakawa, Osamu Irie, Junichi Sakaki, Genji Iwasaki, Rene Lattmann, Martin Missbach, Naoki Teno
  • Macrocyclic Compounds Useful as Bace Inhibitors
    Publication number: 20080132477
    Abstract: The invention relates to novel macrocyclic compounds of the formula (I), in which all of the variables are as defined in the specification, the number of ring atoms included in the macrocyclic ring being 14, 15, 16 or 17, in free base form or in acid addition salt form, to their preparation, to their use as medicaments and to medicaments comprising them.
    Type: Application
    Filed: January 13, 2006
    Publication date: June 5, 2008
    Inventors: Claudia Betschart, Andreas Lerchner, Rainer Machauer, Heinrich Rueger, Marina Tintelnot-Blomley, Siem Jacob Veenstra
  • MACROCYCLIC COMPOUNDS HAVING ASPARTIC PROTEASE INHIBITING ACTIVITY AND PHARMACEUTICAL USES THEREOF
    Publication number: 20080070885
    Abstract: The present invention relates to macro-cyclic compounds of formula (I), wherein R1, is (C1-8)alkyl, (C1-4)alkoxy(C1-4)alkyl, hydroxy(C1-6)alkyl, (C1-4)alkylthio(C1-4)alkyl, (C1-6)alkenyl, (C3-7)cycloalkyl, (C3-7)cycloalkyl(C1-4)alkyl, piperidinyl or pyrrolidinyl, R2 and R4, independently, are hydrogen or optionally substituted (C1-8)alkyl, (C3-7)cycloalkyl, (C3-7)cycloalkyl(C1-4)alkyl, aryl, aryl(C1-4)alkyl, heteroaryl or heteroaryl(C1-4)alkyl, or R2 and R4, together with the nitrogen to which they are attached, form an optionally substituted piperidino, pyrrolidinyl, morpholino or piperazinyl group, R3 is hydrogen or (C1-4)alkyl, X1 is CH2, X2 is CH2, O, S, CO, COO, OCO, NHCO, CONH, or NR, R being hydrogen or (C1-4)alkyl, Y is (C1-8)alkylen or (C1-8)alkylenoxy(C1-6)alkylen, (C1-8)alkenylen or (C1-8)alkenylenoxy(C1-6)alkylen, Ar is a phenyl ring optionally mono- di or trisubstituted by, independently, hydroxy or halogen, whereby X1, and X2 are in meta or para position to each other, and either Z is CO, AA is
    Type: Application
    Filed: November 14, 2007
    Publication date: March 20, 2008
    Inventors: Claudia Betschart, Marina Tintelnot-Blomley