Patents by Inventor Claudia DURANTI

Claudia DURANTI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Mono and bispecific antibody binding to hERG1 and hERG1/integrin beta 1
    Patent number: 11572406
    Abstract: The present invention describes a bispecfic antibody composed of the variable domains (VH and VL) of two antibodies, hERG1 mAb (which binds the extracellular domain S5-P of hERG1) and of ?1 integrin mAb TS2/16 or BV7, which bind the extracellular domain of ?1 integrin. The present invention relates also to a novel anti-hERG1 molecule bearing a Cys in position 95 of the VH domain. The invention describes also their application for diagnostic and therapeutic purposes in oncology and other fields of medical sciences.
    Type: Grant
    Filed: June 29, 2018
    Date of Patent: February 7, 2023
    Assignee: UNIVERSITÀ DEGLI STUDI DI FIRENZE
    Inventors: Annarosa Arcangeli, Claudia Duranti, Laura Carraresi, Silvia Crescioli
  • MONO AND BISPECIFIC ANTIBODY BINDING TO HERG1 AND HERG1/INTEGRIN BETA 1
    Publication number: 20210147574
    Abstract: The present invention describes a bispecfic antibody composed of the variable domains (VH and VL) of two antibodies, hERG1 mAb (which binds the extracellular domain S5-P of hERG1) and of ?1 integrin mAb TS2/16 or BV7, which bind the extracellular domain of ?1 integrin. The present invention relates also to a novel anti-hERG1 molecule bearing a Cys in position 95 of the VH domain. The invention describes also their application for diagnostic and therapeutic purposes in oncology and other fields of medical sciences.
    Type: Application
    Filed: June 29, 2018
    Publication date: May 20, 2021
    Inventors: Annarosa ARCANGELI, Claudia DURANTI, Laura CARRARESI, Silvia CRESCIOLI