Patents by Inventor Claudia Ferrara Koller

Claudia Ferrara Koller has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTIGEN BINDING MOLECULES WITH INCREASED Fc RECEPTOR BINDING AFFINITY AND EFFECTOR FUNCTION
    Publication number: 20160076009
    Abstract: The present invention relates to antigen binding molecules (ABMs). In particular embodiments, the present invention relates to recombinant monoclonal antibodies, including chimeric, primatized or humanized antibodies specific for human CD20. In addition, the present invention relates to nucleic acid molecules encoding such ABMs, and vectors and host cells comprising such nucleic acid molecules. The invention further relates to methods for producing the ABMs of the invention, and to methods of using these ABMs in treatment of disease. In addition, the present invention relates to ABMs with modified glycosylation having improved therapeutic properties, including antibodies with increased Fc receptor binding and increased effector function.
    Type: Application
    Filed: July 31, 2015
    Publication date: March 17, 2016
    Inventors: Pablo UMAÑA, Peter BRÜNKER, Claudia FERRARA KOLLER, Tobias SUTER, Ursula PÜNTENER, Ekkehard MÖSSNER
  • BISPECIFIC ANTIBODIES SPECIFIC FOR FAP AND DR5, ANTIBODIES SPECIFIC FOR DR5 AND METHODS OF USE
    Publication number: 20140370019
    Abstract: The present invention relates to bispecific antibodies comprising at least one antigen binding site specific for DR5 and at least one antigen binding site specific for FAP, antibodies specific for DR5, methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof.
    Type: Application
    Filed: April 1, 2014
    Publication date: December 18, 2014
    Applicant: ROCHE GLYCART AG
    Inventors: Peter Bruenker, Sherif Daouti, Ningping Feng, Claudia Ferrara Koller, Guy Georges, Sandra Grau-Richards, Ralf Hosse, Christian Klein, Maximiliane Koenig, Joerg Moelleken, Ekkehard Moessner, Huifeng Niu, Kathryn E. Packman, Valeria Runza, Stefan Seeber, Pablo Umana, Inja Waldhauer, Huisheng Wang, Barbara Weiser
  • BISPECIFIC DEATH RECEPTOR AGONISTIC ANTIBODIES
    Publication number: 20120184718
    Abstract: The present invention relates to bispecific antibodies comprising a first antigen binding site specific for a death receptor and a second antigen binding site specific for a second antigen, methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof.
    Type: Application
    Filed: September 27, 2010
    Publication date: July 19, 2012
    Applicant: Roche Glycart AG
    Inventors: Peter Bruenker, Claudia Ferrara Koller, Sandra Grau, Sylvia Herter, Christoph Lampert, Ekkehard Moessner, Pablo Umana, Inja Waldhauer
  • HUMAN Fc GAMMA RECEPTOR III
    Publication number: 20110183354
    Abstract: The present invention relates to the field of human immunoglobulin receptors, specifically the glycostructure of a human Fc gamma receptor IIIa recombinantly expressed in human embryonic kidney cells and Chinese hamster ovary cells.
    Type: Application
    Filed: March 1, 2011
    Publication date: July 28, 2011
    Inventors: ULRICH BRINKMANN, PETER BRUENKER, CLAUDIA FERRARA KOLLER, MARTIN LANZENDOERFER, JOERG THOMAS REGULA, TILMAN SCHLOTHAUER, STEFAN SEEBER, ANNE ZECK
  • HUMAN Fc GAMMA RECEPTOR III
    Publication number: 20080248510
    Abstract: The present invention relates to the field of human immunoglobulin receptors, specifically the glycostructure of a human Fc gamma receptor IIIa recombinantly expressed in human embryonic kidney cells and Chinese hamster ovary cells.
    Type: Application
    Filed: March 27, 2008
    Publication date: October 9, 2008
    Inventors: Ulrich Brinkmann, Peter Bruenker, Claudia Ferrara Koller, Martin Lanzendoerfer, Joerg Thomas Regula, Tilman Schlothauer, Stefan Seeber, Anne Zeck
  • Antigen binding molecules having modified Fc regions and altered binding to Fc receptors
    Publication number: 20070111281
    Abstract: The present invention is directed to antigen binding molecules, including antibodies, comprising a Fc region having one or more amino acid modifications, wherein the antigen binding molecule exhibits altered binding to one or more Fc receptors as a result of the modification(s). The invention is further directed to polynucleotides and vectors encoding such antigen binding molecules, to host cells comprising the same, to methods for making the antigen binding molecules of the invention, and to their use in the treatment of various diseases and disorders, e.g., cancers.
    Type: Application
    Filed: May 9, 2006
    Publication date: May 17, 2007
    Applicant: GLYCART BIOTECHNOLOGY AG
    Inventors: Peter Sondermann, Claudia Ferrara Koller, Peter Brunker, Fiona Stuart, Pablo Umana