Patents by Inventor Claudia Hirth-Dietrich

Claudia Hirth-Dietrich has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of sGC stimulators, sGC activators, alone and combinations with PDE5 inhibitors for the treatment of systemic sclerosis (SSc)
    Patent number: 10189856
    Abstract: The use of sGC stimulators, sGC activators alone, or in combination with PDE5 inhibitors for the prevention and treatment of fibrotic diseases, such as systemic sclerosis, scleroderma, and the concomitant fibrosis of internal organs.
    Type: Grant
    Filed: May 24, 2011
    Date of Patent: January 29, 2019
    Assignee: Adverio Pharma GMBH
    Inventors: Claudia Hirth-Dietrich, Peter Sandner, Johannes-Peter Stasch, Andreas Knorr, Georges Von Degenfeld, Michael Hahn, Markus Follmann
  • THE USE OF SGC STIMULATORS, SGC ACTIVATORS, ALONE AND COMBINATIONS WITH PDE5 INHIBITORS FOR THE TREATMENT OF DIGITAL ULCERS (DU) CONCOMITANT TO SYSTEMIC SCLEROSIS (SSC)
    Publication number: 20180169095
    Abstract: Use of sGC stimulators, sGC activators alone, or in combination with PDE5 inhibitors for the prevention and healing of Digital Ulcers which are concomitant to fibrotic diseases, such as systemic sclerosis and scleroderma.
    Type: Application
    Filed: May 2, 2016
    Publication date: June 21, 2018
    Applicant: Bayer Pharma Aktiengesellschaft
    Inventors: Claudia HIRTH-DIETRICH, Peter SANDNER, Johannes-Peter STASCH, Michael HAHN, Markus FOLLMANN, Alexandros VAKALOPOULOS
  • TOPICAL OPHTHALMOLOGICAL PHARMACEUTICAL COMPOSITION CONTAINING REGORAFENIB
    Publication number: 20150328145
    Abstract: The present invention relates to topical ophthalmological pharmaceutical compositions containing regorafenib, a hydrate, solvate or pharmaceutically acceptable salt thereof or a polymorph thereof but without hydrophobic silica and its process of preparation and its use for treating ophthalmological disorders.
    Type: Application
    Filed: December 21, 2013
    Publication date: November 19, 2015
    Applicant: BAYER HEALTHCARE LLC
    Inventors: Michael BOTTGER, Georges VON DEGENFELD, Julia FREUNDLIEB, Claudia HIRTH-DIETRICH, Joerg KELDENICH, Jurgen KLAR, Uwe MUENSTER, Andreas OHM, Annett RICHTER, Bernd RIEDL
  • TOPICAL OPHTHALMOLOGICAL PHARMACEUTICAL COMPOSITION CONTAINING SUNITINIB
    Publication number: 20150174096
    Abstract: The present invention relates to topical ophthalmological pharmaceutical compositions containing sunitinib, a hydrate, solvate or pharmaceutically acceptable salt thereof or a polymorph thereof and its process of preparation and its use for treating ophthalmological disorders.
    Type: Application
    Filed: June 10, 2013
    Publication date: June 25, 2015
    Applicant: Bayer Healthcare LLC
    Inventors: Michael Bottger, Georges Von Degenfeld, Julia Freundlieb, Claudia Hirth-Dietrich, Joerg Keldenich, Jurgen Klar, Uwe Muenster, Andreas Ohm, Annett Richter, Bernd Riedl, Joachim Telser
  • TOPICAL OPHTHALMOLOGICAL PHARMACEUTICAL COMPOSITION CONTAINING CEDIRANIB
    Publication number: 20150165028
    Abstract: The present invention relates to topical ophthalmological pharmaceutical compositions containing cediranib, a hydrate, solvate or pharmaceutically acceptable salt thereof or a polymorph thereof and its process of preparation and its use for treating ophthalmological disorders.
    Type: Application
    Filed: June 10, 2013
    Publication date: June 18, 2015
    Applicant: Bayer Healthcare LLC
    Inventors: Michael Bottger, Georges Von Degenfeld, Julia Freundlieb, Claudia Hirth-Dietrich, Joerg Keldenich, Jurgen Klar, Uwe Muenster, Andreas Ohm, Annett Richter, Bernd Riedl, Joachim Telser
  • Topical Ophthalmological Pharmaceutical Composition containing Axitinib
    Publication number: 20150164790
    Abstract: The present invention relates to topical ophthalmological pharmaceutical compositions containing axitinib, a hydrate, solvate or pharmaceutically acceptable salt thereof or a polymorph thereof and its process of preparation and its use for treating ophthalmological disorders.
    Type: Application
    Filed: June 10, 2013
    Publication date: June 18, 2015
    Applicant: BAYER HEALTHCARE LLC
    Inventors: Michael Böttger, Georges Degenfeld, Julia Freundlieb, Claudia Hirth-Dietrich, Joerg Keldenich, Jürgen Klar, Uwe Muenster, Andreas Ohm, Annett Richter, Bernd Riedl, Joachim Telser
  • Topical Ophthalmological Pharmaceutical Composition containing Pazopanib
    Publication number: 20150141448
    Abstract: The present invention relates to topical ophthalmological pharmaceutical compositions containing pazopanib, a hydrate, solvate or pharmaceutically acceptable salt thereof or a polymorph thereof and its process of preparation and its use for treating ophthalmological disorders.
    Type: Application
    Filed: June 10, 2013
    Publication date: May 21, 2015
    Applicant: BAYER HEALTHCARE LLC
    Inventors: Michael Böttger, Georges Degenfeld, Julia Freundlieb, Claudia Hirth-Dietrich, Joerg Keldenich, Jürgen Klar, Uwe Muenster, Andreas Ohm, Annett Richter, Bernd Riedl, Joachim Telser
  • DIPEPTOID PRODRUGS AND THEIR USE
    Publication number: 20150133364
    Abstract: The present application relates to prodrug derivatives of 2-amino-6-({[2-(4-chlorophenyl)-1,3-thiazol-4-yl]methyl}thio)-4-[4-(2-hydroxyethoxy)phenyl]pyridine-3,5-dicarbonitrile, processes for their preparation, their use for the treatment and/or prophylaxis of diseases, and their use for the manufacture of medicaments for the treatment and/or prophylaxis of diseases, especially of cardiovascular disorders.
    Type: Application
    Filed: January 16, 2015
    Publication date: May 14, 2015
    Inventors: Hans-Georg LERCHEN, Ursula KRENZ, Jörg KELDENICH, Nicole DIEDRICHS, Thomas KRAHN, Claudia HIRTH-DIETRICH, Barbara ALBRECHT-KÜPPER
  • Dipeptoid prodrugs and their use
    Patent number: 8957017
    Abstract: The present application relates to prodrug derivatives of 2-amino-6-({[2-(4-chlorophenyl)-1,3-thiazol-4-yl]methyl}thio)-4-[4-(2-hydroxyethoxy)phenyl]pyridine-3,5-dicarbonitrile, processes for their preparation, their use for the treatment and/or prophylaxis of diseases, and their use for the manufacture of medicaments for the treatment and/or prophylaxis of diseases, especially of cardiovascular disorders.
    Type: Grant
    Filed: March 19, 2014
    Date of Patent: February 17, 2015
    Assignee: Bayer Intellectual Property GmbH
    Inventors: Hans-Georg Lerchen, Ursula Krenz, Jörg Keldenich, Nicole Diedrichs, Thomas Krahn, Claudia Hirth-Dietrich, Barbara Albrecht-Küpper
  • TOPICAL OPHTHALMOLOGICAL PHARMACEUTICAL COMPOSITION CONTAINING REGORAGENIB
    Publication number: 20140296301
    Abstract: The present invention relates to topical ophthalmological pharmaceutical compositions containing regorafenib, a hydrate, solvate or pharmaceutically acceptable salt thereof or a polymorph thereof and its process of preparation and its use for treating ophthalmological disorders.
    Type: Application
    Filed: June 26, 2012
    Publication date: October 2, 2014
    Applicants: BAYER PHARMA AKTIENGESELLSCHAFT, BAYER INTELLECTUAL PROPERTY GMBH
    Inventors: Michael Bottger, Georges Von Degenfeld, Julia Freundlieb, Claudia Hirth-Dietrich, Joerg Keldenich, Jurgen Klar, Uwe Muenster, Andreas Ohm, Annett Richter, Bernd Riedl
  • Topical Ophthalmological Pharmaceutical Composition containing Sorafenib
    Publication number: 20140235678
    Abstract: The present invention relates to topical ophthalmological pharmaceutical compositions containing sorafenib or a pharmaceutically acceptable salt thereof or a polymorph, hydrate or solvate thereof and its process of preparation and its use for treating ophthalmological disorders.
    Type: Application
    Filed: June 26, 2012
    Publication date: August 21, 2014
    Applicant: BAYER HEALTHCARE LLC
    Inventors: Michael Böttger, Julia Freundlieb, Claudia Hirth-Dietrich, Jürgen Klar, Uwe Muenster, Andreas Ohm, Bernd Riedl
  • DIPEPTOID PRODRUGS AND THEIR USE
    Publication number: 20140206879
    Abstract: The present application relates to prodrug derivatives of 2-amino-6-({[2-(4-chlorophenyl)-1,3-thiazol-4-yl]methyl}thio)-4-[4-(2-hydroxyethoxy)phenyl]pyridine-3,5-dicarbonitrile, processes for their preparation, their use for the treatment and/or prophylaxis of diseases, and their use for the manufacture of medicaments for the treatment and/or prophylaxis of diseases, especially of cardiovascular disorders.
    Type: Application
    Filed: March 19, 2014
    Publication date: July 24, 2014
    Applicant: BAYER INTELLECTUAL PROPERTY GmbH
    Inventors: Hans-Georg LERCHEN, Ursula KRENZ, Jörg KELDENICH, Nicole DIEDRICHS, Thomas KRAHN, Claudia HIRTH-DIETRICH, Barbara ALBRECHT-KÜPPER
  • TOPICAL OPHTHALMOLOGICAL PHARMACEUTICAL COMPOSITION CONTAINING REGORAFENIB
    Publication number: 20140179745
    Abstract: The present invention relates to topical ophthalmological pharmaceutical compositions containing regorafenib, a hydrate, solvate or pharmaceutically acceptable salt thereof or a polymorph thereof but without hydrophobic silica and its process of preparation and its use for treating ophthalmological disorders.
    Type: Application
    Filed: December 16, 2013
    Publication date: June 26, 2014
    Applicant: BAYER HEALTHCARE LLC
    Inventors: Michael BOTTGER, Georges VON DEGENFELD, Julia FREUNDLIEB, Claudia HIRTH-DIETRICH, Joerg KELDENICH, Jurgen KLAR, Uwe MUENSTER, Andreas OHM, Annett RICHTER, Bernd RIEDL
  • Dipeptoid prodrugs and the use thereof
    Patent number: 8703696
    Abstract: The present application relates to prodrug derivatives of 2-amino-6-({[2-(4-chlorophenyl)-1,3-thiazol-4-yl]methyl}thio)-4-[4-(2-hydroxyethoxy)phenyl]pyridine-3,5-dicarbonitrile, processes for their preparation, their use for the treatment and/or prophylaxis of diseases, and their use for the manufacture of medicaments for the treatment and/or prophylaxis of diseases, especially of cardiovascular disorders.
    Type: Grant
    Filed: July 23, 2008
    Date of Patent: April 22, 2014
    Assignee: Bayer Intellectual Property GmbH
    Inventors: Hans-Georg Lerchen, Ursula Krenz, Joerg Keldenich, Nicole Diedrichs, Thomas Krahn, Claudia Hirth-Dietrich, Barbara Albrecht-Küpper
  • Human TIMP-1 Antibodies
    Publication number: 20140086935
    Abstract: Human antibodies that bind to TIMP-1 can be used as reagents to diagnose and treat disorders in which TIMP-1 is elevated, such as liver fibrosis, alcoholic liver disease, cardiac fibrosis, acute coronary syndrome, lupus nephritis, glomerulosclerotic renal disease, benign prostate hypertrophy, colon cancer, lung cancer, and idiopathic pulmonary fibrosis.
    Type: Application
    Filed: November 26, 2013
    Publication date: March 27, 2014
    Inventors: Clark Pan, Andreas M. Knorr, Michael Schauer, Claudia Hirth-Dietrich, Sabine Kraft, Barbara Krebs
  • Use of sGC stimulators, sGC activators, alone and combinations with PDE5 inhibitors for the treatment of systemic sclerosis (SSc).
    Publication number: 20140038956
    Abstract: The use of sGC stimulators, sGC activators alone, or in combination with PDE5 inhibitors for the prevention and treatment of fibrotic diseases, such as systemic sclerosis, scleroderma, and the concomitant fibrosis of internal organs.
    Type: Application
    Filed: May 24, 2011
    Publication date: February 6, 2014
    Applicant: BAYER INTELLECTUAL PROPERTY GMBH
    Inventors: Claudia Hirth-Dietrich, Peter Sandner, Johannes-Peter Stasch, Andreas Knorr, Georges Von Degenfeld, Michael Hahn, Markus Follmann
  • HUMAN TIMP-1 ANTIBODIES
    Publication number: 20130302340
    Abstract: Human antibodies that bind to TIMP-1 can be used as reagents to diagnose and treat disorders in which TIMP-1 is elevated, such as liver fibrosis, alcoholic liver disease, cardiac fibrosis, acute coronary syndrome, lupus nephritis, glomerulosclerotic renal disease, benign prostate hypertrophy, colon cancer, lung cancer, and idiopathic pulmonary fibrosis.
    Type: Application
    Filed: March 28, 2013
    Publication date: November 14, 2013
    Inventors: Clark Pan, Andreas M. Knorr, Michael Schauer, Claudia Hirth-Dietrich, Sabine Kraft, Barbara Krebs
  • PRODRUGS AND THE USE THEREOF
    Publication number: 20120122820
    Abstract: The present application relates to prodrug derivatives of 2-amino-6-({[2-(4-chlorophenyl)-1,3-thiazol-4-yl]methyl}thio)-4-[4-(2-hydroxyethoxy)phenyl]pyridine-3,5-dicarbonitrile, processes for their preparation, their use for the treatment and/or prophylaxis of diseases, and their use for the manufacture of medicaments for the treatment and/or prophylaxis of diseases, especially of cardiovascular disorders.
    Type: Application
    Filed: July 23, 2008
    Publication date: May 17, 2012
    Inventors: Nicole Diedrichs, Thomas Krahn, Ursula Krenz, Jörg Keldenich, Hanna Tinel, Claudia Hirth-Dietrich, Hans-Georg Lerchen
  • DIPEPTOID PRODRUGS AND THE USE THEREOF
    Publication number: 20110294718
    Abstract: The present application relates to prodrug derivatives of 2-amino-6-({[2-(4-chlorophenyl)-1,3-thiazol-4-yl]methyl}thio)-4-[4-(2-hydroxyethoxy)phenyl]pyridine-3,5-dicarbonitrile, processes for their preparation, their use for the treatment and/or prophylaxis of diseases, and their use for the manufacture of medicaments for the treatment and/or prophylaxis of diseases, especially of cardiovascular disorders.
    Type: Application
    Filed: July 23, 2008
    Publication date: December 1, 2011
    Inventors: Hans-Georg Lerchen, Ursula Krenz, Joerg Keldenich, Nicole Diedrichs, Thomas Krahn, Claudia Hirth-Dietrich, Barbara Albrecht-Küpper
  • HUMAN TIMP-1 ANTIBODIES
    Publication number: 20110262429
    Abstract: Human antibodies that bind to TIMP-1 can be used as reagents to diagnose and treat disorders in which TIMP-1 is elevated, such as liver fibrosis, alcoholic liver disease, cardiac fibrosis, acute coronary syndrome, lupus nephritis, glomerulosclerotic renal disease, benign prostate hypertrophy, colon cancer, lung cancer, and idiopathic pulmonary fibrosis.
    Type: Application
    Filed: June 30, 2011
    Publication date: October 27, 2011
    Inventors: CLARK PAN, ANDREAS M. KNORR, MICHAEL SCHAUER, CLAUDIA HIRTH-DIETRICH, SABINE KRAFT, BARBARA KREBS