Patents by Inventor Claudia Lorenzo

Claudia Lorenzo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Human mini-antibody cytotoxic for tumor cells which express the ERB-B2 receptor
    Publication number: 20070258985
    Abstract: The invention refers to a fully human miniantibody (scFv), called Erbicin, specific for the receptor ErbB2, with a pharmacological, in particular antitumour, activity. It has been obtained from a larger fagmidic library (Griffin 1.) (19) of human synthetic scFv by panning (affinity selection on antigen) carried out on live cells that express various levels of ErbB2. The invention relates also to the DNA and aniino acid sequences of said antibody, to the procedure for isolating it, to its use in therapy.
    Type: Application
    Filed: July 10, 2002
    Publication date: November 8, 2007
    Inventors: Giuseppe D'Alessio, Renata Piccoli, Claudia Lorenzo, Donald Palmer, Mary Ritter