Patents by Inventor Claudine Bruck

Claudine Bruck has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • FUSION PROTEINS COMPRISING HIV-1 TAT AND/OR NEF PROTEINS
    Publication number: 20100215681
    Abstract: The invention provides (a) an HIV Tat protein or derivative thereof linked to either (i) a fusion partner or (ii) an HIV Nef protein or derivative thereof; or (b) an HIV Nef protein or derivative thereof linked to either (i) a fusion partner or (ii) an HIV Tat protein or derivative thereof; or (c) an HIV Nef protein or derivative thereof linked to an HIV Tat protein or derivative thereof and a fusion partner. The invention further provides for a nucleic acid encoding such a protein and a host cell, such as Pichia Pastoris, transformed with the aforementioned nucleic acid.
    Type: Application
    Filed: April 26, 2010
    Publication date: August 26, 2010
    Inventors: Claudine BRUCK, Stephane Andre Georges Godart, Martine Marchand
  • FUSION PROTEINS COMPRISING HIV-1 TAT AND/OR NEF PROTEINS
    Publication number: 20090053291
    Abstract: The invention provides (a) an HIV Tat protein or derivative thereof linked to either (i) a fusion partner or (ii) an HIV Nef protein or derivative thereof; or (b) an HIV Nef protein or derivative thereof linked to either (i) a fusion partner or (ii) an HIV Tat protein or derivative thereof; or (c) an HIV Nef protein or derivative thereof linked to an HIV Tat protein or derivative thereof and a fusion partner. The invention further provides for a nucleic acid encoding such a protein and a host cell, such as Pichia Pastoris, transformed with the aforementioned nucleic acid.
    Type: Application
    Filed: October 30, 2007
    Publication date: February 26, 2009
    Inventors: Claudine BRUCK, Stephane Andre Georges Godart, Martine Marchand
  • FUSION PROTEINS COMPRISING HIV-1 TAT AND/OR NEF PROTEINS
    Publication number: 20080102080
    Abstract: The invention provides (a) an HIV Tat protein or derivative thereof linked to either (i) a fusion partner or (ii) an HIV Nef protein or derivative thereof; or (b) an HIV Nef protein or derivative thereof linked to either (i) a fusion partner or (ii) an HIV Tat protein or derivative thereof; or (c) an HIV Nef protein or derivative thereof linked to an HIV Tat protein or derivative thereof and a fusion partner. The invention further provides for a nucleic acid encoding such a protein and a host cell, such as Pichia Pastoris, transformed with the aforementioned nucleic acid.
    Type: Application
    Filed: October 30, 2007
    Publication date: May 1, 2008
    Inventors: Claudine BRUCK, Stephane GODART, Martine MARCHAND
  • FUSION PROTEINS COMPRISING HIV-1 TAT AND/OR NEF PROTEINS
    Publication number: 20080089929
    Abstract: The invention provides (a) an HIV Tat protein or derivative thereof linked to either (i) a fusion partner or (ii) an HIV Nef protein or derivative thereof; or (b) an HIV Nef protein or derivative thereof linked to either (i) a fusion partner or (ii) an HIV Tat protein or derivative thereof; or (c) an HIV Nef protein or derivative thereof linked to an HIV Tat protein or derivative thereof and a fusion partner. The invention further provides for a nucleic acid encoding such a protein and a host cell, such as Pichia Pastoris, transformed with the aforementioned nucleic acid.
    Type: Application
    Filed: October 2, 2007
    Publication date: April 17, 2008
    Inventors: Claudine BRUCK, Stephane Andre Godart, Martine Marchand
  • FUSION PROTEINS COMPRISING HIV-1 TAT AND/OR NEF PROTEINS
    Publication number: 20080089902
    Abstract: The invention provides (a) an HIV Tat protein or derivative thereof linked to either (i) a fusion partner or (ii) an HIV Nef protein or derivative thereof; or (b) an HIV Nef protein or derivative thereof linked to either (i) a fusion partner or (ii) an HIV Tat protein or derivative thereof; or (c) an HIV Nef protein or derivative thereof linked to an HIV Tat protein or derivative thereof and a fusion partner. The invention further provides for a nucleic acid encoding such a protein and a host cell, such as Pichia Pastoris, transformed with the aforementioned nucleic acid.
    Type: Application
    Filed: October 2, 2007
    Publication date: April 17, 2008
    Inventors: Claudine BRUCK, Stephane Godart, Martine Marchand
  • Recombinant allergen with reduced enzymatic activity
    Patent number: 7348009
    Abstract: The present invention provides a novel treatment for allergy comprising a recombinant allergen with reduced enzymatic activity, thereby reducing the potential for an allergic response upon contact with a wild-type allergen.
    Type: Grant
    Filed: November 16, 1998
    Date of Patent: March 25, 2008
    Assignee: SmithKline Beecham Biologicals, s.a.
    Inventors: Claudine Bruck, Alex Bollen, Paul Jacobs, Marc Georges Francis Massaer
  • Mage-3 and NY-ESO-1 Based Polyvalent Vaccine for Cancer Immunotherapy
    Publication number: 20070243196
    Abstract: The present invention provides novel vaccine formulations for the treatment of cancer antigens. The vaccine comprises a modified MAGE-3 antigen, a NY-ESO-1 antigen, and an adjuvant comprising a saponin and a immunostimulatory oligonucleotide.
    Type: Application
    Filed: May 2, 2005
    Publication date: October 18, 2007
    Applicant: GLAXOSMITHKLINE BIOLOGICALS S.A.
    Inventors: Claudine Bruck, Vincent Brichard, Remi Palmantier, Melinda Meaders
  • Vaccine Compositions Comprising An Interleukin 18 And Saponin Adjuvant System
    Publication number: 20070212329
    Abstract: This invention relates to a combination therapy that finds utility in the treatment or prophylaxis of infectious diseases, cancers, autoimmune diseases and related conditions. In particular, the combination therapy comprises the administration of a TH-1 cytokine, in particular, IL-18, and an immunogenic composition, in particular, a vaccine, comprising an antigen and a saponin adjuvant. In particular, the invention relates to the use of IL-18 or bioactive fragment or variant thereof and an immunogenic composition comprising a tumour-associated antigen and a saponin adjuvant, for the treatment of preneoplasic lesions or cancer.
    Type: Application
    Filed: October 11, 2004
    Publication date: September 13, 2007
    Inventors: Claudine Bruck, Catherine Marie Gerard, Zdenka Jonak
  • Immunogenic Compositions
    Publication number: 20070212328
    Abstract: The invention relates to a combination therapy that finds utility in the treatment or prophylaxis of infectious diseases, cancers, autoimmune diseases and related conditions. In particular, the combination therapy comprises the administration of a TH-1 cytokine, in particular IL-18, and an immunogenic composition, in particular a vaccine, comprising an antigen and a CpG adjuvant.
    Type: Application
    Filed: October 11, 2004
    Publication date: September 13, 2007
    Inventors: Claudine Bruck, Catherine Gerard, Zdenka Jonak
  • CASB618 polynucleotides and polypeptides and their use
    Publication number: 20060052593
    Abstract: CASB618 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing CASB618 polypeptides and polynucleotides in diagnostics, and vaccines for prophylactic and therapeutic treatment of cancers, particularly ovarian and colon cancers, autoimmune diseases, and related conditions.
    Type: Application
    Filed: August 9, 2005
    Publication date: March 9, 2006
    Inventors: Claudine Bruck, Jean-Pol Cassart, Thierry Coche, Carlota Vinals Y De Bassols
  • Fusion proteins comprising HIV-1 Tat and/or Nef proteins
    Publication number: 20050033022
    Abstract: The invention provides (a) an HIV Tat protein or derivative thereof linked to either (i) a fusion partner or (ii) an HIV Nef protein or derivative thereof; or (b) an HIV Nef protein or derivative thereof linked to either (i) a fusion partner or (ii) an HIV Tat protein or derivative thereof; or (c) an HIV Nef protein or derivative thereof linked to an HIV Tat protein or derivative thereof and a fusion partner.
    Type: Application
    Filed: October 16, 2003
    Publication date: February 10, 2005
    Inventors: Claudine Bruck, Stephane Godart, Martine Marchand
  • Method to enhance an immune response of nucleic acid vaccination
    Publication number: 20030072768
    Abstract: This invention provides a method to enhance an immune response of nucleic acid vaccination by simultaneous administration of a polynucleotide and a polypeptide of interest.
    Type: Application
    Filed: November 12, 2002
    Publication date: April 17, 2003
    Applicant: SmithKline Beecham Biologicals, s.a.
    Inventors: Wilfried Dalemans, Marcelle Van Mechelen, Claudine Bruck, Martin Friede
  • Method to enhance an immune response of nucleic acid vaccination
    Patent number: 6500432
    Abstract: This invention provides a method to enhance an immune response of nucleic acid vaccination by simultaneous administration of a polynucleotide and a polypeptide of interest.
    Type: Grant
    Filed: June 12, 2000
    Date of Patent: December 31, 2002
    Assignee: SmithKline Beecham Biologicals, S.A.
    Inventors: Wilfried Dalemans, Marcelle Van Mechelen, Claudine Bruck, Martin Friede
  • Recombinant papillomavirus vaccine and method for production and treatment
    Publication number: 20020182221
    Abstract: The present invention relates to fusions proteins, comprising a protein or part of a protein that provides T helper epitopes and an antigen from a human-papilloma virus. In particular the invention relates to fusion proteins comprising an E6 or E7 protein from HPV strain 16 or 18 linked to protein D from Haemophilus influenza B. The invention also provides vaccine compositions that are useful in the treatment or prophylaxis of human papilloma induced tumors.
    Type: Application
    Filed: November 1, 2001
    Publication date: December 5, 2002
    Applicant: SmithKline Beecham Biologicals
    Inventors: Claudine Bruck, Teresa Cabezon Silva, Anne-Marie Eva Fernande Delisse, Catherine Marie Ghislaine Gerard, Angela Lombardo-Bencheikh
  • Recombinant papillomavirus vaccine and method for production and treatment
    Patent number: 6342224
    Abstract: The present invention relates to fusions proteins, comprising a protein or part of a protein that provides T helper epitopes and an antigen from a human-papilloma virus. In particular the invention relates to fusion proteins comprising an E6 or E7 protein from HPV strain 16 or 18 linked to protein D from Haemophilus influenza B. The invention also provides vaccine compositions that are useful in the treatment or prophylaxis of human papilloma induced tumours.
    Type: Grant
    Filed: February 18, 2000
    Date of Patent: January 29, 2002
    Assignee: SmithKline Beecham Biologicals, S.A.
    Inventors: Claudine Bruck, Teresa Cabezon Silva, Anne-Marie Eva Fernande Delisse, Catherine Marie Ghislaine Gerard, Angela Lombardo-Bencheikh