Patents by Inventor Claudine Lavergne
Claudine Lavergne has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9649404Abstract: The present invention relates to an injectable bone cement for filling bones with mechanical properties equivalent to those of vertebral spongy bone comprising 70 to 99 wt. % of an acrylic polymer combined with an inorganic type radiopaque compound and 1 to 30 wt. % of calibrated hydrophilic flexible solid particles, said calibrated hydrophilic flexible solid particles being chosen from gelatin, poly(glycerol sebacate) or a mixture thereof. A bone cement according to the invention is particularly intended for vertebroplasty, kyphoplasty or cementoplasty.Type: GrantFiled: March 5, 2009Date of Patent: May 16, 2017Assignee: TEKNIMEDInventors: Alain Leonard, Claudine Lavergne, Cyril Sender, Benoit Donazzon
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Patent number: 8536243Abstract: The invention relates to a system for preparing a polymerized bone cement, including two components reacting with each other when they are mixed to form a solid polymer material. The first component may include a biocompatible acrylic polymer and an initiator capable of initiating a polymerization reaction. The second component may include a monomer capable of dissolving an acrylic polymer, a polymerization activator and a polymerization inhibitor, system in which the second component also includes a biocompatible acrylic polymer dissolved in said monomer, identical or different from the polymer of the first component with an average molar mass greater than 1,000,000 g/mol and a residual initiator content of less than 0.1% to form a gel with determined viscosity. Another object of the invention is a composition designed to constitute the second component of as system used to prepare such cement.Type: GrantFiled: April 23, 2010Date of Patent: September 17, 2013Assignee: Teknimed SASInventors: Alain Leonard, Cyril Sender, Claudine Lavergne, Benoît Donazzon
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Patent number: 8449621Abstract: A ready-for-use polymer cement spacer device for the replacement of a permanent joint prosthesis during a two-stage replacement, includes a shank includes for attachment for placing to the supporting bone and a head in the joint region. The spacer device includes two complementary members incorporating rigid members for assembly between them, the first member being loaded with a first active substance and the second member being loaded with a second active substance. The first and second active substances are preferably antibiotics, selected from gentamycin, trobamycin, vancomycin, erythromycin, fucidin, tetracycline or other suitable antibiotics. The temporary joint implant maintains a suitable space for the time necessary for the operation of replacing a permanent prosthesis to prevent tissues from occupying the space released by removal of the permanent prosthesis and ensures effective treatment of resistant infections by local treatment of the joint area through at least two different active substances.Type: GrantFiled: March 2, 2007Date of Patent: May 28, 2013Assignee: TeknimedInventors: Alain Leonard, Claudine Lavergne, Jean-françois Oglaza
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Patent number: 8173721Abstract: A fluid cement for medical use for bone reconstruction, in particular for filling the vertebral body, and a binary composition which is intended for the preparation of such a cement. A device for conditioning the binary composition, and a method of preparing a bone cement from a binary composition. The fluid cement according to the invention comprises: a) approximately 70% to 85% by weight of a polymer comprising a polymethylmethacrylate and a methylmethacrylate monomer, and b) approximately from 15 to 30% by weight of a radio-opaque composition. Preferably, the radio-opaque composition comprises a radio-opacifier, such as a barium sulphate and zirconium dioxide, in a mixture with a calcium phosphate, for example hydroxyapatite.Type: GrantFiled: June 21, 2004Date of Patent: May 8, 2012Assignee: TeknimedInventors: Claudine Lavergne, Alain Leonard
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Patent number: 8153704Abstract: The invention provides a fluid cement for medical use for bone reconstruction, in particular for filling the vertebral body, and a binary composition which is intended for the preparation of such a cement. The invention also provides a device for conditioning the binary composition, and a method of preparing a bone cement from a binary composition. The fluid cement according to the invention comprises: a) approximately 60% to 85% by weight of a polymer comprising a polymethylmethacrylate and a methylmethacrylate monomer and b) approximately from 15 to 40% by weight of a radio-opaque composition. Preferably, the radio-opaque composition comprises a radio-opacifier, such as barium sulfate and zirconium dioxide, in a mixture with a calcium phosphate, for example apatite hydroxide.Type: GrantFiled: June 4, 2007Date of Patent: April 10, 2012Assignee: TeknimedInventors: Claudine Lavergne, Alain Leonard
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Publication number: 20110237705Abstract: The invention relates to a system for preparing a polymerized bone cement, including two components reacting with each other when they are mixed to form a solid polymer material. The first component may include a biocompatible acrylic polymer and an initiator capable of initiating a polymerization reaction. The second component may include a monomer capable of dissolving an acrylic polymer, a polymerization activator and a polymerization inhibitor, system in which the second component also includes a biocompatible acrylic polymer dissolved in said monomer, identical or different from the polymer of the first component with an average molar mass greater than 1,000,000 g/mol and a residual initiator content of less than 0.1% to form a gel with determined viscosity. Another object of the invention is a composition designed to constitute the second component of as system used to prepare such cement.Type: ApplicationFiled: April 23, 2010Publication date: September 29, 2011Inventors: Alain LEONARD, Cyril Sender, Claudine Lavergne, Benoît Donazzon
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Publication number: 20100228358Abstract: The present invention relates to an injectable bone cement for filling bones with mechanical properties equivalent to those of vertebral spongy bone comprising 70 to 99 wt. % of an acrylic polymer combined with an inorganic type radiopaque compound and 1 to 30 wt. % of calibrated hydrophilic flexible solid particles, said calibrated hydrophilic flexible solid particles being chosen from gelatin, poly(glycerol sebacate) or a mixture thereof. A bone cement according to the invention is particularly intended for vertebroplasty, kyphoplasty or cementoplasty.Type: ApplicationFiled: March 5, 2009Publication date: September 9, 2010Applicant: TEKNIMEDInventors: Alain Leonard, Claudine Lavergne, Cyril Sender, Benoit Donazzon
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Publication number: 20080058950Abstract: A ready-for-use polymer cement spacer device for the replacement of a permanent joint prosthesis during a two-stage replacement, includes a shank includes for attachment for placing to the supporting bone and a head in the joint region. The spacer device includes two complementary members incorporating rigid members for assembly between them, the first member being loaded with a first active substance and the second member being loaded with a second active substance. The first and second active substances are preferably antibiotics, selected from gentamycin, trobamycin, vancomycin, erythromycin, fucidin, tetracycline or other suitable antibiotics. The temporary joint implant maintains a suitable space for the time necessary for the operation of replacing a permanent prosthesis to prevent tissues from occupying the space released by removal of the permanent prosthesis and ensures effective treatment of resistant infections by local treatment of the joint area through at least two different active substances.Type: ApplicationFiled: March 2, 2007Publication date: March 6, 2008Inventors: Alain Leonard, Claudine Lavergne, Jean-Francois Oglaza
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Publication number: 20080044374Abstract: The invention provides a fluid cement for medical use for bone reconstruction, in particular for filling the vertebral body, and a binary composition which is intended for the preparation of such a cement. The invention also provides a device for conditioning the binary composition, and a method of preparing a bone cement from a binary composition. The fluid cement according to the invention comprises: a) approximately 60% to 85% by weight of a polymer comprising a polymethylmethacrylate and a methylmethacrylate monomer and b) approximately from 15 to 40% by weight of a radio-opaque composition. Preferably, the radio-opaque composition comprises a radio-opacifier, such as barium sulfate and zirconium dioxide, in a mixture with a calcium phosphate, for example apatite hydroxide.Type: ApplicationFiled: June 4, 2007Publication date: February 21, 2008Inventors: Claudine Lavergne, Alain Leonard
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Publication number: 20050256220Abstract: A fluid cement for medical use for bone reconstruction, in particular for filling the vertebral body, and a binary composition which is intended for the preparation of such a cement. A device for conditioning the binary composition, and a method of preparing a bone cement from a binary composition. The fluid cement according to the invention comprises: a) approximately 70% to 85% by weight of a polymer comprising a polymethylmethacrylate and a methylmethacrylate monomer and b) approximately from 15 to 30% by weight of a radio-opaque composition. Preferably, the radio-opaque composition comprises a radio-opacifier, such as barium sulphate and zirconium dioxide, in a mixture with a calcium phosphate, for example apatite hydroxide.Type: ApplicationFiled: June 21, 2004Publication date: November 17, 2005Applicant: CERAVIC SASInventors: Claudine Lavergne, Alain Leonard