Patents by Inventor Claudine Serradeil-Le Gal

Claudine Serradeil-Le Gal has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Indolin-2-one Pyridine Derivatives, Preparation And Therapeutic Use Thereof
    Publication number: 20070185166
    Abstract: The disclosure concerns indolin-2-one pyridine compounds of general formula (I): wherein R0, R1, R2, R3, R4, Z and B have the meanings given in the description, and pharmaceutically acceptable salts thereof; and also pharmaceutical compositions comprising, processes for making and methods of using said compounds.
    Type: Application
    Filed: March 16, 2007
    Publication date: August 9, 2007
    Applicant: SANOFI-AVENTIS
    Inventors: Loic Foulon, Claudine Serradeil-Le Gal, Gerard Valette
  • Acyloxypyrrolidine derivatives, preparation thereof and application thereof in therapeutic
    Patent number: 7202267
    Abstract: The invention relates to acyloxypyrrolidine derivatives of general formula (I): in which: R1 represents a hydrogen atom, a (C1–C6)alkyl, a (C3–C6)cycloalkyl, a group —CH2CH2COOH or a group —NR2R3; R2 and R3 each represent, independently, a hydrogen atom or a (C1–C6)alkyl. Also disclosed and claimed are the method of preparation of the compounds of the invention and their application in therapeutics.
    Type: Grant
    Filed: January 19, 2005
    Date of Patent: April 10, 2007
    Assignee: Sanofi-aventis
    Inventors: Alain Aulombard, Georges Garcia, Antoine Pradines, Claudine Serradeil-Le Gal, Jean Wagnon
  • NOVEL 1,3-DIHYDRO-2H-INDOL-2-ONE DERIVATIVES, PROCESS FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
    Publication number: 20070004703
    Abstract: The invention relates to compounds of formula: as well as the possible salts thereof with mineral or organic acids, and the solvates and/or hydrates thereof, which have affinity for and selectivity towards the V1b receptors or towards both the V1b and V1a receptors of arginine-vasopressin. The invention also relates to the process for preparing them, to the intermediate compounds of formula (II) that are useful for preparing them, to pharmaceutical compositions containing them and to their use for the preparation of medicinal products.
    Type: Application
    Filed: August 3, 2006
    Publication date: January 4, 2007
    Applicant: SANOFI-AVENTIS
    Inventors: Richard Roux, Claudine Serradeil-Le Gal, Bernard Tonnerre, Jean Wagnon
  • 1,3-dihydro-2H-indol-2one derivatives, process for preparing them and pharmaceutical compositions containing them
    Patent number: 7129240
    Abstract: The invention relates to compounds of formula: as well as the possible salts thereof with mineral or organic acids, and the solvates and/or hydrates thereof, which have affinity for and selectivity towards the V1b receptors or towards both the V1b and V1a receptors of arginine-vasopressin. The invention also relates to the process for preparing them, to the intermediate compounds of formula (II) that are useful for preparing them, to pharmaceutical compositions containing them and to their use for the preparation of medicinal products.
    Type: Grant
    Filed: April 29, 2004
    Date of Patent: October 31, 2006
    Assignee: Sanofi-Aventis
    Inventors: Richard Roux, Claudine Serradeil-le Gal, Bernard Tonnerre, Jean Wagnon
  • Phenylsulfonyl-1,3-dihydro-2h-indole-2-one derivatives, their preparation and their therapeutic use
    Patent number: 7119086
    Abstract: The invention relates to compounds of formula: and also to the salts thereof with mineral or organic acids, and the solvates and/or hydrates thereof, with affinity for and selectivity towards the arginine-vasopressin V1b receptors and/or for the ocytocin receptors and, furthermore, for certain compounds, affinity for the V1a receptors. The invention also relates to the process for preparing them, to the intermediate compounds of formula (IV) that are useful for preparing them, to pharmaceutical compositions containing them and to their use for preparing medicinal products.
    Type: Grant
    Filed: July 15, 2002
    Date of Patent: October 10, 2006
    Assignee: Sanofi-Aventis
    Inventors: Alain Di Malta, Georges Garcia, Richard Roux, Bruno Schoentjes, Claudine Serradeil-Le Gal, Bernard Tonnerre, Jean Wagnon
  • Acyloxypyrrolidine derivatives, preparation thereof and application thereof in therapeutic
    Publication number: 20050192335
    Abstract: The invention relates to acyloxypyrrolidine derivatives of general formula (I): in which: R1 represents a hydrogen atom, a (C1-C6)alkyl, a (C3-C6)cycloalkyl, a group —CH2CH2COOH or a group —NR2R3; R2 and R3 each represent, independently, a hydrogen atom or a (C1-C6)alkyl. Also disclosed and claimed are the method of preparation of the compounds of the invention and their application in therapeutics.
    Type: Application
    Filed: January 19, 2005
    Publication date: September 1, 2005
    Applicant: Sanofi-Aventis
    Inventors: Alain Aulombard, Georges Garcia, Antoine Pradines, Claudine Serradeil-Le Gal, Jean Wagnon
  • Novel 1,3-dihydro-2H-indol-2-one derivatives, process for preparing them and pharmaceutical compositions containing them
    Publication number: 20050176770
    Abstract: The invention relates to compounds of formula: and to solvates and/or hydrates thereof, with affinity for and selectivity towards the V1b receptors or both the V1b and V1a receptors of arginine-vasopressin. The invention also relates to a process for preparing them, to the intermediate compounds of formula (II) which are useful for preparing them, to pharmaceutical compositions containing them and to their use for preparing medicinal products.
    Type: Application
    Filed: February 24, 2005
    Publication date: August 11, 2005
    Applicant: Sanofi-Aventis
    Inventors: Richard Roux, Claudine Serradeil-Le Gal, Jean Wagnon
  • 1,3-dihydro-2H-indol-2-one derivatives, method for preparing same and pharmaceutical compositions containing them
    Patent number: 6864277
    Abstract: The invention relates to compounds of formula: and to solvates and/or hydrates thereof, with affinity for and selectivity towards the Vreceptors or both the V1b and V1a receptors of arginine-vasopressin. The invention also relates to a process for preparing them, to the intermediate compounds of formula (II) which are useful for preparing them, to pharmaceutical compositions containing them and to their use for preparing medicinal products.
    Type: Grant
    Filed: June 19, 2001
    Date of Patent: March 8, 2005
    Assignee: Sanofi-Synthelabo
    Inventors: Richard Roux, Claudine Serradeil-Le Gal, Jean Wagnon
  • Novel 1,3-dihydro-2H-indol-2one derivatives, process for preparing them and pharmaceutical compositions containing them
    Publication number: 20040209938
    Abstract: The invention relates to compounds of formula: 1
    Type: Application
    Filed: April 29, 2004
    Publication date: October 21, 2004
    Inventors: Richard Roux, Claudine Serradeil-Le Gal, Bernard Tonnerre, Jean Wagnon
  • Phenylsulfonyl-1,3-dihydro-2h-indole-2-one derivatives, their preparation and their therapeutic use
    Publication number: 20040180878
    Abstract: The invention relates to compounds of formula: 1
    Type: Application
    Filed: January 16, 2004
    Publication date: September 16, 2004
    Inventors: Alain Di Malta, Georges Garcia, Richard Roux, Bruno Schoentjes, Claudine Serradeil-Le Gal, Bernard Tonnerre, Jean Wagnon
  • 1,3-dihydro-2h-indol-2-one derivatives and their use as ligands for V1b and V1a arginine-vasopressin receptors
    Patent number: 6730695
    Abstract: The invention relates to compounds of formula: as well as the possible salts thereof with mineral or organic acids, and the solvates and/or hydrates thereof, which have affinity for and selectivity towards the V1b receptors or towards both the V1b and V1a receptors of arginine-vasopressin. The invention also relates to the process for preparing them, to the intermediate compounds of formula (II) that are useful for preparing them, to pharmaceutical compositions containing them and to their use for the preparation of medicinal products.
    Type: Grant
    Filed: July 24, 2002
    Date of Patent: May 4, 2004
    Assignee: Sanofi-Synthelabo
    Inventors: Richard Roux, Claudine Serradeil-Le Gal, Bernard Tonnerre, Jean Wagnon
  • Novel indolin-2-one derivatives, their preparation and the pharmaceutical compositions comprising them
    Publication number: 20040059132
    Abstract: The present invention relates to novel indolin-2-one derivatives of formula: 1
    Type: Application
    Filed: September 3, 2003
    Publication date: March 25, 2004
    Inventors: Loic Foulon, Georges Garcia, Claudine Serradeil-Le Gal, Gerard Valette
  • Indolin-2-one derivatives, preparation and their use as ocytocin receptor ligands
    Patent number: 6673790
    Abstract: The present invention relates to novel indolin-2-one derivatives of formula: to the preparation and to the pharmaceutical compositions comprising them. These compounds have an affinity for oxytocin receptors.
    Type: Grant
    Filed: October 2, 2002
    Date of Patent: January 6, 2004
    Assignee: Sanofi-Synthelabo
    Inventors: Loïc Foulon, Georges Garcia, Claudine Serradeil-Le Gal, Gérard Valette
  • 1,3-dihydro-2H-indol-2-one derivatives, preparation method and pharmaceutical composition containing them
    Patent number: 6624164
    Abstract: The invention relates to compounds of formula: and their solvates and/or hydrates exhibiting affinity for the arginine-vasopressin V1b receptors or for both V1b and V1a receptors. The invention also relates to their process of preparation, to the intermediate compounds of formula (II) of use for their preparation, to the pharmaceutical compositions comprising them and to their use for the preparation of medicaments.
    Type: Grant
    Filed: November 25, 2002
    Date of Patent: September 23, 2003
    Assignee: Sanofi-Synthelabo
    Inventors: Bruno Schoentjes, Claudine Serradeil-Le Gal, Jean Wagnon
  • Novel 1,3-dihydro-2h-indol-2-one derivatives, method for preparing same and pharmaceutical compositions containing them
    Publication number: 20030162767
    Abstract: The invention relates to compounds of formula: 1
    Type: Application
    Filed: December 16, 2002
    Publication date: August 28, 2003
    Inventors: Richard Roux, Claudine Serradeil-Le Gal, Jean Wagnon
  • NOVEL 1,3-DIHYDRO-2H-INDOL-2-ONE DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITION CONTAINING THEM
    Publication number: 20030139413
    Abstract: The invention relates to compounds of formula: 1
    Type: Application
    Filed: November 25, 2002
    Publication date: July 24, 2003
    Inventors: Bruno Schoentjes, Claudine Serradeil-Le Gal, Jean Wagnon
  • 1,3-dihydro-2h-indol-2-one, preparation method and pharmaceutical compositions containing same
    Patent number: 6596732
    Abstract: The invention relates to compounds of formula: and their solvates and/or hydrates exhibiting an affinity and a selectivity for arginine-vasopressin V1b receptors or for both V1b and V1a receptors.
    Type: Grant
    Filed: August 12, 2002
    Date of Patent: July 22, 2003
    Assignee: Sanofi-Synthelabo
    Inventors: Claudine Serradeil-Le Gal, Bernard Tonnerre, Jean Wagnon
  • Novel 1,3-dihydro-2h-indol-2-one derivatives and their use as ligands for v1b and v1a arginine-vasopressin receptors
    Publication number: 20030114683
    Abstract: The invention relates to compounds of formula: 1
    Type: Application
    Filed: July 24, 2002
    Publication date: June 19, 2003
    Inventors: Richard Roux, Claudine Serradeil-Le Gal, Bernard Tonnerre, Jean Wagnon
  • Novel 1,3-dihydro-2h-indol-2-one, preparation method and pharmaceutical compositions containing same
    Publication number: 20030109545
    Abstract: The invention relates to compounds of formula: 1
    Type: Application
    Filed: August 12, 2002
    Publication date: June 12, 2003
    Inventors: Claudine Serradeil-Le-Gal, Bernhard Tonnerre, Jean Wagnon
  • Cosmetic composition containing a neuropeptide Y receptor antagonist
    Patent number: 6313128
    Abstract: This invention relates to a cosmetic composition containing at least one NPY-antagonist component mixed with an excipient for cosmetic preparations.
    Type: Grant
    Filed: February 9, 2000
    Date of Patent: November 6, 2001
    Assignee: Sanofi-Synthelabo
    Inventors: Elisabeth Blanc-Ferras, Francoise Bono-Colombie, Bernard Breda, Jean Courregelongue, Catherine Ducasse, Remy Mounier, Paul Raymond, Michel Sabadie, Claudine Serradeil-Le-Gal, Vilain Pol, Jean-Marie Pereillo