Patents by Inventor Claudio Aquino

Claudio Aquino has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • KINASE MODULATORS AND METHODS OF USE THEREOF
    Publication number: 20240025906
    Abstract: The invention provides compounds that modulate the activity of protein kinases that are associated with human diseases, disorders, and conditions. In particular, compounds of the invention inhibit TYK2, a member of the Janus Kinase (JAK) family of non-receptor protein kinases.
    Type: Application
    Filed: June 16, 2023
    Publication date: January 25, 2024
    Inventors: Zhonghua Pei, Gyanendra Kumar, Anh Truong, Claudio Aquino, Derek Kejia Wu, Andrew Tasker
  • SUBSTITUTED BENZENECARBOXAMIDES AS IL-17A MODULATORS
    Publication number: 20230141212
    Abstract: The disclosure herein provides compounds and pharmaceutical compositions of the structure of Formula I: for the modulation of IL-17A, useful for the treatment of inflammatory conditions, such as psoriasis.
    Type: Application
    Filed: December 28, 2022
    Publication date: May 11, 2023
    Inventors: Paul R. FATHEREE, Martin S. LINSELL, John R. JACOBSEN, Wouter A. VAN DER LINDEN, Timothy J. CHURCH, Claudio AQUINO, Margot G. PAULICK
  • SUBSTITUTED BENZENECARBOXAMIDES AS IL-17A MODULATORS
    Publication number: 20230145481
    Abstract: The disclosure herein provides compounds and pharmaceutical compositions of the structure of Formula I: for the modulation of IL-17A, useful for the treatment of inflammatory conditions, such as psoriasis.
    Type: Application
    Filed: December 28, 2022
    Publication date: May 11, 2023
    Inventors: Paul R. FATHEREE, Martin S. LINSELL, John R. JACOBSEN, Wouter A. VAN DER LINDEN, Timothy J. CHURCH, Claudio AQUINO, Margot G. PAULICK
  • IL-17 LIGANDS AND USES THEREOF
    Publication number: 20230053746
    Abstract: Provided herein are novel ligands and pharmaceutical compositions thereof which modulate IL-17A. Also provided are methods for preparing the IL-17A modulators. Such compounds may be useful in the treatment and/or prevention of, for example, inflammation, cancer or autoimmune disease.
    Type: Application
    Filed: July 15, 2022
    Publication date: February 23, 2023
    Inventors: Paul R. FATHEREE, Martin S. LINSELL, John R. JACOBSEN, Wouter VAN DER LINDEN, Timothy J. CHURCH, Claudio AQUINO, Margot PAULICK
  • IL-17 ligands and uses thereof
    Patent number: 11447468
    Abstract: Provided herein are novel ligands and pharmaceutical compositions thereof which modulate IL-17A. Also provided are methods for preparing the IL-17A modulators. Such compounds may be useful in the treatment and/or prevention of, for example, inflammation, cancer or autoimmune disease.
    Type: Grant
    Filed: February 6, 2020
    Date of Patent: September 20, 2022
    Assignee: DICE ALPHA, INC.
    Inventors: Paul R. Fatheree, Martin S. Linsell, John R. Jacobsen, Wouter Van der Linden, Timothy J. Church, Claudio Aquino, Margot Paulick
  • SUBSTITUTED BENZENECARBOXAMIDES AS IL-17A MODULATORS
    Publication number: 20220235038
    Abstract: The disclosure herein provides compounds and pharmaceutical compositions of the structure of Formula I: for the modulation of IL-17A, useful for the treatment of inflammatory conditions, such as psoriasis.
    Type: Application
    Filed: January 27, 2022
    Publication date: July 28, 2022
    Inventors: Paul R. FATHEREE, Martin S. LINSELL, John R. JACOBSEN, Wouter A. VAN DER LINDEN, Timothy J. CHURCH, Claudio AQUINO, Margot G. PAULICK
  • Substituted benzenecarboxamides as IL-17A modulators
    Patent number: 11274094
    Abstract: The disclosure herein provides compounds and pharmaceutical compositions for the modulation of IL-17A useful for the treatment of inflammatory conditions, such as psoriasis.
    Type: Grant
    Filed: December 11, 2020
    Date of Patent: March 15, 2022
    Assignee: DICE ALPHA, INC.
    Inventors: Paul R. Fatheree, Martin S. Linsell, John R. Jacobsen, Wouter A. Van Der Linden, Timothy J. Church, Claudio Aquino, Margot G. Paulick
  • IL-17A MODULATORS AND USES THEREOF
    Publication number: 20210101886
    Abstract: The disclosure herein provides compounds and pharmaceutical compositions for the modulation of IL-17A useful for the treatment of inflammatory conditions, such as psoriasis.
    Type: Application
    Filed: December 11, 2020
    Publication date: April 8, 2021
    Inventors: Paul R. FATHEREE, Martin S. LINSELL, John R. JACOBSEN, Wouter A. VAN DER LINDEN, Timothy J. CHURCH, Claudio AQUINO, Margot G. PAULICK
  • IL-17 Ligands And Uses Thereof
    Publication number: 20200247785
    Abstract: Provided herein are novel ligands and pharmaceutical compositions thereof which modulate IL-17A. Also provided are methods for preparing the IL-17A modulators. Such compounds may be useful in the treatment and/or prevention of, for example, inflammation, cancer or autoimmune disease.
    Type: Application
    Filed: February 6, 2020
    Publication date: August 6, 2020
    Inventors: Paul R. Fatheree, Martin S. Linsell, John R. Jacobsen, Wouter Van der Linden, Timothy J. Church, Claudio Aquino, Margot Paulick