Patents by Inventor Claudio BRUSCHINI

Claudio BRUSCHINI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250216306
    Abstract: An apparatus for detecting one or more chemicals in a sample, the apparatus including: a scanning unit including a light source configured to scan the sample using a light beam having a linear-shaped illumination; a dispersive element configured to receive light from the sample and disperse the received light spatially in a parallel manner; a spatial light modulator configured to receive the dispersed light and select one or more wavelength bands of the dispersed light; and a detection unit including a one-dimensional array of detectors configured to receive the selected one or more wavelength bands and detect the one or more chemicals in the sample based on the selected one or more wavelength bands, each detector of the array of detectors being a photon detector having a detection surface having a dimension below 50 ?m, the dimension being in a direction of the linear-shaped illumination.
    Type: Application
    Filed: March 24, 2023
    Publication date: July 3, 2025
    Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, COLLEGE DE FRANCE, ECOLE NORMALE SUPERIEURE, SORBONNE UNIVERSITE
    Inventors: Hilton BARBOSA DE AGUIAR, Claudio BRUSCHINI, Edoardo CHARBON, Samuel BURRI
  • Patent number: 12249669
    Abstract: The present invention relates to a photodetector array for capturing image data, comprising: —photodetector cells arranged on a substrate, each including a single-photon avalanche diode, wherein the active areas of the photodetector cells are neighbored along a hexagonal grid; —microlenses, having a hexagonal or circular shape, each arranged on one photodetector cell to focus light onto the photodiode.
    Type: Grant
    Filed: November 4, 2019
    Date of Patent: March 11, 2025
    Assignee: Ecole Polytechnique Federale De Lausanne
    Inventors: Michel Ivan Antolovic, Claudio Bruschini, Edoardo Charbon
  • Patent number: 12204082
    Abstract: A light microscope has a light source for illuminating a specimen, a sensor array comprised of photon-counting detector elements for measuring detection light coming from the specimen, and a control device for controlling the sensor array. The control device is configured for flexibly binning the photon-counting detector elements into one or more super-pixels.
    Type: Grant
    Filed: April 9, 2019
    Date of Patent: January 21, 2025
    Assignees: Carl Zeiss Microscopy GmbH, Ecole Polytechnique Federale de Lausanne
    Inventors: Tiemo Anhut, Daniel Schwedt, Ivan Michel Antolovic, Claudio Bruschini, Edoardo Charbon
  • Patent number: 12192656
    Abstract: The invention relates to an image sensor comprising a photodetector array including neighboring photodetector elements, each photodetector element comprising: —a photodetector cell having a photodiode and a reset unit; —a cell control unit coupled with the photodetector cell and configured to reset the photodiode by means of the reset unit; wherein the cell control unit is configured to asynchronously effect resetting of the photodiode after a given dead time after detection of a photon.
    Type: Grant
    Filed: August 1, 2019
    Date of Patent: January 7, 2025
    Assignee: Ecole Polytechnique Federale De Lausanne
    Inventors: Ivan Michel Antolovic, Claudio Bruschini, Edoardo Charbon
  • Patent number: 12055700
    Abstract: A light microscope has a light source for illuminating a specimen, a photon-counting detector array with a plurality of photon-counting detector elements for measuring detection light coming from the specimen, wherein the photon-counting detector elements are configured to output respective measured photon count rates, and a control device for controlling the photon-counting detector array. The control device is configured to individually influence the measurable photon count rates which are simultaneously measurable with different photon-counting detector elements and/or which are consecutively measurable with the same photon-counting detector element. Furthermore, in an imaging method the measurable photon count rates of photon-counting detector elements are individually influenced to increase the signal-to-noise ratio for the photon-counting detector array.
    Type: Grant
    Filed: January 25, 2019
    Date of Patent: August 6, 2024
    Assignee: Carl Zeiss Microscopy GmbH
    Inventors: Tiemo Anhut, Daniel Schwedt, Ivan Michel Antolovic, Claudio Bruschini, Edoardo Charbon
  • Patent number: 11982566
    Abstract: A system for photon correlation of an illuminated object and/or a light source is provided. The system includes a light source for illuminating the object and an optical system having an object-facing side configured to face the object or the light source and a projection side with the projection side having a focal plane. The system also includes a single-chip single photon avalanche photodiode (SPAD) array arranged at the focal plane and a timing circuit associated with the single-chip SPAD array for measuring arrival times of photons detected by the single-chip SPAD array.
    Type: Grant
    Filed: February 28, 2020
    Date of Patent: May 14, 2024
    Assignees: ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL), YEDA RESEARCH & DEVELOPMENT CO. LTD.
    Inventors: Ivan Michel Antolovic, Claudio Bruschini, Edoardo Charbon, Gur Lubin, Ron Tenne, Dan Oron, Uri Rossman
  • Publication number: 20230288687
    Abstract: A method for operating a light microscope comprises emitting and guiding a plurality of illumination light beams towards a specimen (6) to form a plurality of separated illumination light spots (2A, 2B, 2C, 2D) at the specimen; and guiding detection light beams (11) coming from the illumination light spots (2A, 2B, 2C, 2D) to a detector (10) comprising a plurality of sensor arrays (31-34). Each sensor array (31-34) comprises photon-counting detector elements (40), and detection light beams (11) from different illumination light spots (2A, 2B, 2C, 2D) are guided to different sensor arrays (31-34). Measured signals from the sensor arrays (31-34) are analysed to determine positional information about the light spots (15) on the sensor arrays (31 -34). It is adjusted where the light spots (15) hit the sensor arrays (31-34) based on the positional information. A corresponding light microscope is furthermore disclosed.
    Type: Application
    Filed: July 28, 2020
    Publication date: September 14, 2023
    Inventors: Tiemo ANHUT, Ivan Michel ANTOLOVIC, Daniel SCHWEDT, Edoardo CHARBON, Claudio BRUSCHINI
  • Publication number: 20220384671
    Abstract: The present invention relates to a photodetector array for capturing image data, comprising: photodetector cells arranged on a substrate, each including a single-photon avalanche diode, wherein the active areas of the photodetector cells are neighbored along a hexagonal grid; microlenses, having a hexagonal or circular shape, each arranged on one photodetector cell to focus light onto the photodiode.
    Type: Application
    Filed: November 4, 2019
    Publication date: December 1, 2022
    Inventors: Michel Ivan ANTOLOVIC, Claudio BRUSCHINI, Edoardo CHARBON
  • Publication number: 20220264047
    Abstract: The invention relates to an image sensor comprising a photodetector array including neighboring photodetector elements, each photodetector element comprising:—a photodetector cell having a photodiode and a reset unit;—a cell control unit coupled with the photodetector cell and configured to reset the photodiode by means of the reset unit; wherein the cell control unit is configured to asynchronously effect resetting of the photodiode after a given dead time after detection of a photon.
    Type: Application
    Filed: August 1, 2019
    Publication date: August 18, 2022
    Inventors: Ivan Michel ANTOLOVIC, Claudio BRUSCHINI, Edoardo CHARBON
  • Publication number: 20220206275
    Abstract: A light microscope has a light source for illuminating a specimen, a sensor array comprised of photon-counting detector elements for measuring detection light coming from the specimen, and a control device for controlling the sensor array. The control device is configured for flexibly binning the photon-counting detector elements into one or more super-pixels.
    Type: Application
    Filed: April 9, 2019
    Publication date: June 30, 2022
    Applicants: Carl Zeiss Microscopy GmbH, Ecole Polytechnique Federale de Lausanne
    Inventors: Tiemo ANHUT, Daniel SCHWEDT, Ivan Michel ANTOLOVIC, Claudio BRUSCHINI, Edoardo CHARBON
  • Publication number: 20220170784
    Abstract: A system for photon correlation of an illuminated object and/or a light source, including a light source for illuminating the object or to correlate, an optical system having an object-facing side configured to face the object or the light source and a projection side, the projection side having a focal plane, a single-chip single photon avalanche photodiode (SPAD) array arranged at the focal plane, and a timing circuit associated with the single-chip SPAD array for measuring arrival times of photons detected by the single-chip SPAD array.
    Type: Application
    Filed: February 28, 2020
    Publication date: June 2, 2022
    Inventors: Ivan Michel Antolovic, Claudio Bruschini, Edoardo Charbon, Gur Lubin, Ron Tenne, Dan Oron, Uri Rossman
  • Publication number: 20220075171
    Abstract: A light microscope has a light source for illuminating a specimen, a photon-counting detector array with a plurality of photon-counting detector elements for measuring detection light coming from the specimen, wherein the photon-counting detector elements are configured to output respective measured photon count rates, and a control device for controlling the photon-counting detector array. The control device is configured to individually influence the measurable photon count rates which are simultaneously measurable with different photon-counting detector elements and/or which are consecutively measurable with the same photon-counting detector element. Furthermore, in an imaging method the measurable photon count rates of photon-counting detector elements are individually influenced to increase the signal-to-noise ratio for the photon-counting detector array.
    Type: Application
    Filed: January 25, 2019
    Publication date: March 10, 2022
    Applicants: Carl Zeiss Microscopy GmbH, Ecole Polytechnique Federale de Lausanne
    Inventors: Tiemo ANHUT, Daniel SCHWEDT, Ivan Michel ANTOLOVIC, Claudio BRUSCHINI, Edoardo CHARBON