Patents by Inventor Claudio Giuliano

Claudio Giuliano has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ASYMMETRIC UREAS AND MEDICAL USES THEREOF
    Publication number: 20180044293
    Abstract: Disclosed are compounds, compositions and methods for the prevention and/or treatment of diseases which are pathophysiologically mediated by the ghrelin receptor.
    Type: Application
    Filed: July 30, 2017
    Publication date: February 15, 2018
    Inventors: Silvina GARCIA RUBIO, Claudio PIETRA, Claudio GIULIANO, Zhigang LI
  • Benzenesulfonyl-Asymmetric Ureas and Medical Uses Thereof
    Publication number: 20170275301
    Abstract: Benzenesulfonyl-asymmetric ureas are provided for the treatment of conditions modulated by the ghrelin receptor.
    Type: Application
    Filed: March 21, 2017
    Publication date: September 28, 2017
    Inventors: Claudio Giuliano, Antoine Daina, Claudio Pietra
  • Asymmetric ureas and medical uses thereof
    Patent number: 9751836
    Abstract: Disclosed are compounds, compositions and methods for the prevention and/or treatment of diseases which are pathophysiologically mediated by the ghrelin receptor.
    Type: Grant
    Filed: January 8, 2014
    Date of Patent: September 5, 2017
    Assignee: HELSINN HEALTHCARE SA
    Inventors: Silvina Garcia Rubio, Claudio Pietra, Claudio Giuliano, Zhigang Li
  • SUBSTITUTED ASYMMETRIC UREAS AND MEDICAL USES THEREOF
    Publication number: 20170145038
    Abstract: Disclosed are compounds, compositions and methods for the prevention and/or treatment of diseases which are pathophysiologically mediated by the ghrelin receptor. The compounds have the general Formula I: or pharmaceutically acceptable salts thereof.
    Type: Application
    Filed: December 2, 2016
    Publication date: May 25, 2017
    Inventors: Claudio Giuliano, Silvina Garcia Rubio, Antoine Daina, Angelo Guainazzi, Claudio Pietra
  • Substituted 4-Phenyl Pyridines
    Publication number: 20170050993
    Abstract: Disclosed are compounds, compositions and methods for the prevention and/or treatment of diseases which are pathophysiologically mediated by the neurokinin (NK1) receptor.
    Type: Application
    Filed: June 28, 2016
    Publication date: February 23, 2017
    Applicant: Helsinn Healthcare SA
    Inventors: Luca Fadini, Peter Manini, Claudio Pietra, Claudio Giuliano, Emanuela Lovati, Roberta Cannella, Alessio Venturini, Valentino J Stella
  • Asymmetric piperidinyl-substituted ureas as medicines
    Patent number: 9546157
    Abstract: Disclosed are compounds, compositions and methods for the prevention and/or treatment of diseases which are pathophysiologically mediated by the ghrelin receptor. The compounds have the general Formula I: or pharmaceutically acceptable salts thereof.
    Type: Grant
    Filed: March 6, 2015
    Date of Patent: January 17, 2017
    Assignee: Helsinn Healthcare SA
    Inventors: Claudio Giuliano, Silvina Garcia Rubio, Antoine Daina, Angelo Guainazzi, Claudio Pietra
  • 4-(5-(2-(3,5-bis(trifluoromethyl)phenyl)-N,2-dimethylpropanamido)-4-(o-tolyl)pyridin-2-yl)-1-methyl-1-((phosphonooxy)methyl)piperazin-1-ium as a neurokinin receptor modulator
    Patent number: 9403772
    Abstract: Compounds and methods for the prevention and/or treatment of diseases which are pathophysiologically mediated by the neurokinin (NK1) receptor, based on 4-(5-(2-(3,5-bis(trifluoromethyl)phenyl)-N,2-dimethylpropanamido)-4-(o-tolyl)3yridine-2-yl)-1-methyl-1-((phosphonooxy)methyl)piperazin-1-ium and pharmaceutically acceptable salts thereof.
    Type: Grant
    Filed: November 28, 2012
    Date of Patent: August 2, 2016
    Assignee: HELSINN HEALTHCARE SA
    Inventors: Luca Fadini, Peter Manini, Claudio Pietra, Claudio Giuliano, Emanuela Lovati, Roberta Cannella, Alessio Venturini, Valentino J Stella
  • p-Substituted Asymmetric Ureas and Medical Uses Thereof
    Publication number: 20150252021
    Abstract: Disclosed are compounds, compositions and methods for the prevention and/or treatment of diseases which are pathophysiologically mediated by the ghrelin receptor. The compounds have the general Formula I: or pharmaceutically acceptable salts thereof.
    Type: Application
    Filed: March 6, 2015
    Publication date: September 10, 2015
    Applicant: Helsinn Healthcare SA
    Inventors: Claudio Giuliano, Silvina Garcia Rubio, Antoine Daina, Angelo Guainazzi, Claudio Pietra
  • Methods of treating emesis
    Patent number: 8895586
    Abstract: Disclosed are compounds, compositions and methods for the prevention and/or treatment of diseases which are pathophysiologically mediated by the neurokinin (NK1) receptor.
    Type: Grant
    Filed: April 17, 2013
    Date of Patent: November 25, 2014
    Inventors: Luca Fadini, Peter Manini, Claudio Pietra, Claudio Giuliano, Emanuela Lovati, Roberta Cannella, Alessio Venturini, Valentino J. Stella
  • ASYMMETRIC UREAS AND MEDICAL USES THEREOF
    Publication number: 20140121210
    Abstract: Disclosed are compounds, compositions and methods for the prevention and/or treatment of diseases which are pathophysiologically mediated by the ghrelin receptor.
    Type: Application
    Filed: January 8, 2014
    Publication date: May 1, 2014
    Applicant: HELSINN HEALTHCARE SA
    Inventors: Silvina GARCIA RUBIO, Claudio PIETRA, Claudio GIULIANO, Zhigang LI
  • Asymmetric ureas and medical uses thereof
    Patent number: 8658797
    Abstract: Disclosed are compounds, compositions and methods for the prevention and/or treatment of diseases which are pathophysiologically mediated by the ghrelin receptor.
    Type: Grant
    Filed: February 24, 2012
    Date of Patent: February 25, 2014
    Assignee: Helsinn Healthcare SA
    Inventors: Silvina Garcia Rubio, Claudio Giuliano, Claudio Pietra, Zhigang Li
  • MODIFIED 4-PHENYL-PYRIDINE DERIVATIVES
    Publication number: 20130231315
    Abstract: Disclosed are compounds, compositions and methods for the prevention and/or treatment of diseases which are pathophysiologically mediated by the neurokinin (NK1) receptor.
    Type: Application
    Filed: April 17, 2013
    Publication date: September 5, 2013
    Applicant: Helsinn Healthcare SA
    Inventors: Luca Fadini, Peter Manini, Claudio Pietra, Claudio Giuliano, Emanuela Lovati, Roberta Cannella, Alessio Venturini, Valentino J. Stell
  • Substituted 4-phenyl pyridines having anti-emetic effect
    Patent number: 8426450
    Abstract: Disclosed are compounds, compositions and methods for the prevention and/or treatment of diseases which are pathophysiologically mediated by the neurokinin (NK1) receptor.
    Type: Grant
    Filed: May 23, 2012
    Date of Patent: April 23, 2013
    Assignee: Helsinn Healthcare SA
    Inventors: Luca Fadini, Peter Manini, Claudio Pietra, Claudio Giuliano, Emanuela Lovati, Roberta Cannella, Alessio Venturini, Valentino J. Stella
  • ASYMMETRIC UREAS AND MEDICAL USES THEREOF
    Publication number: 20120220629
    Abstract: Disclosed are compounds, compositions and methods for the prevention and/or treatment of diseases which are pathophysiologically mediated by the ghrelin receptor.
    Type: Application
    Filed: February 24, 2012
    Publication date: August 30, 2012
    Inventors: Silvina GARCIA RUBIO, Claudio Pietra, Claudio Giuliano, Zhigang Li
  • Modulators of HCV replication
    Patent number: 8012982
    Abstract: The present invention is directed to compounds of formula (I): where X, Y, R1, R2 and R3 are defined therein, which can act as modulators of viral replication and/or virus production, especially of the hepatitis C virus (HCV).
    Type: Grant
    Filed: September 29, 2005
    Date of Patent: September 6, 2011
    Assignee: Istituto di Ricerche Biologia Molecolare P. Angeletti SpA
    Inventors: Immacolata Conte, Caterina Ercolani, Claudio Giuliano, Giovanni Migliaccio, Gessica Filocamo, legal representative, Veronica Suriano, legal representative, Ian Stansfield
  • Modulators of hcv replication
    Publication number: 20090069344
    Abstract: The present invention is directed to compounds of formula (I): where X, Y, R1, R2 and R3 are defined therein, which can act as modulators of viral replication and/or virus production, especially of the hepatitis C virus (HCV).
    Type: Application
    Filed: September 29, 2005
    Publication date: March 12, 2009
    Inventors: Immacolata Conte, Caterina Ercolani, Claudio Giuliano, Giovanni Migliaccio, Ian Stansfield, Gessica Filocamo, Veronica Suriano
  • Dihydroxypyridmidine carboxylic acids as viral polymerase inhibitors
    Patent number: 7091209
    Abstract: A class of 2-aryl-4,5-dihydroxy-6-carboxypyrimidines of formula (I): wherein Ar is an optionally substituted aryl or heterocyclicgroup; as well as compounds of formula (I) which are derivatized at one or more of the 4-hydroxy, 5-hydroxy or 6-carboxy groups; and tautomers thereof, and pharmaceutically acceptable salts or esters thereof; and inhibitors of viral polymerases, especially the hepatitis C virus (HCV) polymerase enzyme
    Type: Grant
    Filed: July 11, 2001
    Date of Patent: August 15, 2006
    Assignee: Merck & Co., Inc.
    Inventors: Cristina Gardelli, Claudio Giuliano, Steven Harper, Uwe Koch, Frank Narjes, Jesus Maria Ontoria Ontoria, Marco Poma, Simona Ponzi, Ian Stansfield, Vincenzo Summa
  • Dihydroxypyrimidine carboxylic acids as viral polymerase inhibitors
    Publication number: 20040106627
    Abstract: A class of 2-aryl-4,5-dihydroxy-6-carboxypyrimidines of formula (I): wherein Ar is an optionally substituted aryl or heterocyclic group; as well as compounds of formula (I) which are derivatised at one or more of the 4-hydroxy, 5-hydroxy or 6-carboxy groups; and tautomers thereof, and pharmaceutically acceptable salts or esters thereof; and inhibitors of viral polymerases, especially the hepatitis C virus (HCV) polymerase enzyme.
    Type: Application
    Filed: July 9, 2003
    Publication date: June 3, 2004
    Inventors: Cristina Gardelli, Claudio Giuliano, Steven Harper, Uwe Koch, Frank Narjes, Jesus Maria Ontoria Ontoria, Marco Poma, Simona Ponzi, Ian Stansfield, Vincenzo Summa
  • Magazine with movable shelves, for the maturation of cakes of synthetic foam material
    Patent number: 4923354
    Abstract: A magazine for the maturation of cakes of synthetic foam material, for a plant served by a conveyor belt bringing the cakes for distribution in the magazine, and by an overhead crane with a gripper intended for lifting a cake from the belt conveyor, for shifting it laterally and for depositing the same into a maturation space, which comprises stands arranged parallel to and at the side of the belt conveyor; each stand comprises a frame which supports a fixed lower shelf whose width and length are adapted to the width and length of the cakes to be received, and above the fixed shelf, at vertical mutual distances somewhat greater than the height of the cakes to be received, a plurality of movable shelves for receiving the cakes; each movable shelf is shiftable between a working position, in which it constitutes a surface whose width and length are adapted to the width and length of the cakes to be received, and a rest position, in which it leaves free the access from above to the shelf lying below.
    Type: Grant
    Filed: October 24, 1988
    Date of Patent: May 8, 1990
    Assignee: Gestioni Riunite Toscana Gomma S.p.A.
    Inventors: Claudio Giuliano, Pier E. Gilardi