Patents by Inventor Claudio Hidalgo-Cantabrana

Claudio Hidalgo-Cantabrana has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NOVEL TYPE I-C CRISPR-CAS SYSTEM FROM CLOSTRIDIA
    Publication number: 20230242893
    Abstract: This invention is directed to recombinant Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) and recombinant nucleic acid constructs encoding clostridia Type I-C CASCADE complexes, expression cassettes and vectors comprising the same, and methods of use thereof for modifying genomes, altering expression, killing one or more cells in a population of cells, and screening or selecting for genomic variants of an organism.
    Type: Application
    Filed: June 9, 2021
    Publication date: August 3, 2023
    Inventors: Rodolphe BARRANGOU, Claudio HIDALGO-CANTABRANA, Matthew A. NETHERY
  • Recombinant type I CRISPR-CAS system
    Patent number: 11680259
    Abstract: This invention relates to recombinant Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) arrays and recombinant nucleic acid constructs encoding Type I-E CASCADE complexes as well as plasmids, retroviruses and bacteriophage comprising the same.
    Type: Grant
    Filed: May 13, 2020
    Date of Patent: June 20, 2023
    Assignee: North Carolina State University
    Inventors: Rodolphe Barrangou, Claudio Hidalgo-Cantabrana
  • RECOMBINANT TYPE I CRISPR-CAS SYSTEM AND USES THEREOF FOR SCREENING FOR VARIANT CELLS
    Publication number: 20220177943
    Abstract: This invention relates to recombinant Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) arrays and recombinant nucleic acid constructs encoding Type I-E CASCADE complexes, plasmids, retroviruses and bacteriophage comprising the same, and methods of use thereof for screening for variant cells of an organism.
    Type: Application
    Filed: September 25, 2019
    Publication date: June 9, 2022
    Inventors: Rodolphe Barrangou, Claudio Hidalgo Cantabrana
  • RECOMBINANT TYPE I CRISPR-CAS SYSTEM AND USES THEREOF FOR KILLING TARGET CELLS
    Publication number: 20220170048
    Abstract: This invention relates to recombinant Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) arrays and recombinant nucleic acid constructs encoding Type I-E CASCADE complexes, plasmids, retroviruses and bacteriophage comprising the same, and methods of use thereof for killing one or more cells in a population of bacterial and/or archaeal cells.
    Type: Application
    Filed: September 25, 2019
    Publication date: June 2, 2022
    Inventors: Rodolphe Barrangou, Claudio Hidalgo Cantabrana
  • RECOMBINANT TYPE I CRISPR-CAS SYSTEM AND USES THEREOF FOR GENOME MODIFICATION AND ALTERATION OF EXPRESSION
    Publication number: 20220056433
    Abstract: This invention is directed to recombinant Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) arrays and recombinant nucleic acid constructs encoding Type 1-E CASCADE complexes, plasmids, retroviruses and bacteriophage comprising the same, and methods of use thereof for modifying genomes and expression. Further disclosed are methods of modifying (editing) the genome of target organisms using the constructs.
    Type: Application
    Filed: September 25, 2019
    Publication date: February 24, 2022
    Inventors: Rodolphe Barrangou, Claudio Hidalgo Cantabrana
  • RECOMBINANT TYPE I CRISPR-CAS SYSTEM
    Publication number: 20200385702
    Abstract: This invention relates to recombinant Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) arrays and recombinant nucleic acid constructs encoding Type I-E CASCADE complexes as well as plasmids, retroviruses and bacteriophage comprising the same.
    Type: Application
    Filed: May 13, 2020
    Publication date: December 10, 2020
    Inventors: Rodolphe Barrangou, Claudio Hidalgo-Cantabrana
  • Recombinant type I CRISPR-Cas system
    Patent number: 10711267
    Abstract: This invention relates to recombinant Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) arrays and recombinant nucleic acid constructs encoding Type I-E CASCADE complexes as well as plasmids, retroviruses and bacteriophage comprising the same.
    Type: Grant
    Filed: September 25, 2019
    Date of Patent: July 14, 2020
    Assignee: NORTH CAROLINA STATE UNIVERSITY
    Inventors: Rodolphe Barrangou, Claudio Hidalgo-Cantabrana
  • RECOMBINANT TYPE I CRISPR-CAS SYSTEM
    Publication number: 20200102551
    Abstract: This invention relates to recombinant Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) arrays and recombinant nucleic acid constructs encoding Type I-E CASCADE complexes as well as plasmids, retroviruses and bacteriophage comprising the same.
    Type: Application
    Filed: September 25, 2019
    Publication date: April 2, 2020
    Inventors: Rodolphe Barrangou, Claudio Hidalgo-Cantabrana