Patents by Inventor Claudio Marelli

Claudio Marelli has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR IN VIVO EVALUATION OF PULMONARY PHYSIOLOGY AND/OR FUNCTION USING NMR SIGNALS OF POLARIZED 129XE
    Publication number: 20110104067
    Abstract: In certain embodiments, methods of the present invention obtain dynamic data sets of an NMR spectroscopy signal of polarized 129Xe in a selected structure, environment, or system. The signal data can be used to evaluate: (a) the physiology of a membrane or tissue; (b) the operational condition or function of a body system or portion thereof (when at rest or under stimulation); and/or (c) the efficacy of a therapeutic treatment used to treat a diagnosed disorder, disease, or condition. Thus, the present invention provides methods for screening and/or diagnosing a respiratory, cardiopulmonary disorder or disease such as chronic heart failure, and/or methods for monitoring the efficacy of therapeutics administered to subject to treat the disorder or disease.
    Type: Application
    Filed: January 10, 2011
    Publication date: May 5, 2011
    Applicant: MEDI-PHYSICS, INC.
    Inventors: Bastiaan Driehuys, Margaret Hall, Claudio Marelli, Sven Mansson, Jan Wolber
  • Methods for in vivo evaluation of pulmonary physiology and/or function using NMR signals of polarized Xe
    Patent number: 7867477
    Abstract: In certain embodiments, methods of the present invention obtain dynamic data sets of an NMR spectroscopy signal of polarized 129Xe in a selected structure, environment, or system. The signal data can be used to evaluate: (a) the physiology of a membrane or tissue; (b) the operational condition or function of a body system or portion thereof (when at rest or under stimulation); and/or (c) the efficacy of a therapeutic treatment used to treat a diagnosed disorder, disease, or condition. Thus, the present invention provides methods for screening and/or diagnosing a respiratory, cardiopulmonary disorder or disease such as chronic heart failure, and/or methods for monitoring the efficacy of therapeutics administered to subject to treat the disorder or disease.
    Type: Grant
    Filed: January 16, 2007
    Date of Patent: January 11, 2011
    Assignee: Medi-Physics Inc.
    Inventors: Bastiaan Driehuys, Margaret Hall, Claudio Marelli, Sven Mansoon, Jan Wolber
  • Methods for In Vivo Evaluation of Pulmonary Physiology And/Or Function Using NMR Signals of Polarized 129Xe
    Publication number: 20070110669
    Abstract: In certain embodiments, methods of the present invention obtain dynamic data sets of an NMR spectroscopy signal of polarized 129Xe in a selected structure, environment, or system. The signal data can be used to evaluate: (a) the physiology of a membrane or tissue; (b) the operational condition or function of a body system or portion thereof (when at rest or under stimulation); and/or (c) the efficacy of a therapeutic treatment used to treat a diagnosed disorder, disease, or condition. Thus, the present invention provides methods for screening and/or diagnosing a respiratory, cardiopulmonary disorder or disease such as chronic heart failure, and/or methods for monitoring the efficacy of therapeutics administered to subject to treat the disorder or disease.
    Type: Application
    Filed: January 16, 2007
    Publication date: May 17, 2007
    Inventors: Bastiaan Driehuys, Margaret Hall, Claudio Marelli, Sven Mansoon, Jan Wolber
  • Methods for in vivo evaluation of pulmonary physiology and/or function using NMR signals of polarized Xe
    Patent number: 7179450
    Abstract: In certain embodiments, methods of the present invention obtain dynamic data sets of an NMR spectroscopy signal of polarized 129Xe in a selected structure, environment, or system. The signal data can be used to evaluate: (a) the physiology of a membrane or tissue; (b) the operational condition or function of a body system or portion thereof (when at rest or under stimulation); and/or (c) the efficacy of a therapeutic treatment used to treat a diagnosed disorder, disease, or condition. Thus, the present invention provides methods for screening and/or diagnosing a respiratory, cardiopulmonary disorder or disease such as chronic heart failure, and/or methods for monitoring the efficacy of therapeutics administered to subject to treat the disorder or disease.
    Type: Grant
    Filed: January 31, 2003
    Date of Patent: February 20, 2007
    Assignee: Medi-Physics, Inc.
    Inventors: Bastiaan Driehuys, Margaret Hall, Claudio Marelli, Sven Mansson, Jan Wolber
  • Methods for in vivo evaluation of physiological conditions and/or organ or system function including methods to evaluate cardiopulmonary disorders such as chronic heart failure using polarized 129 Xe
    Patent number: 6991777
    Abstract: In certain embodiments, methods of the present invention obtain NMR spectroscopy signal data that corresponds to the behavior of the polarized 129Xe at a selected site(s) in selected environments in vivo. The gas exchange signal data can be used to evaluate: (a) the thickness of a barrier, such as a membrane, lining, wall or width of a lumen; (b) the operational condition or function of a membrane, body system or portion thereof; (c) cerebral perfusion; and/or (c) the efficacy of a therapeutic treatment used to treat a diagnosed disorder, disease, or condition. Thus, the present invention provides methods for screening and/or diagnosing a disorder or disease, and/or methods for monitoring the efficacy of therapeutics administered to subject to treat a disorder or disease.
    Type: Grant
    Filed: September 6, 2002
    Date of Patent: January 31, 2006
    Assignee: Medi-Physics, Inc.
    Inventors: Bastiaan Driehuys, Margaret Hall, Claudio Marelli
  • Methods for in vivo evaluation of physiological conditions and/or organ or system function including methods to evaluate cardiopulmonary disorders such as chronic heart failure using polarized 129Xe
    Publication number: 20060002856
    Abstract: In certain embodiments, methods of the present invention obtain NMR spectroscopy signal data that corresponds to the behavior of the polarized 129Xe at a selected site(s) in selected environments in vivo. The gas exchange signal data can be used to evaluate: (a) the thickness of a barrier, such as a membrane, lining, wall or width of a lumen; (b) the operational condition or function of a membrane, body system or portion thereof; (c) cerebral perfusion; and/or (c) the efficacy of a therapeutic treatment used to treat a diagnosed disorder, disease, or condition. Thus, the present invention provides methods for screening and/or diagnosing a disorder or disease, and/or methods for monitoring the efficacy of therapeutics administered to subject to treat a disorder or disease.
    Type: Application
    Filed: September 12, 2005
    Publication date: January 5, 2006
    Inventors: Bastiaan Driehuys, Margaret Hall, Claudio Marelli
  • Methods for in vivo evaluation of pulmonary physiology and/or function using NMR signals of polarized Xe
    Publication number: 20040005273
    Abstract: In certain embodiments, methods of the present invention obtain dynamic data sets of an NMR spectroscopy signal of polarized 129Xe in a selected structure, environment, or system. The signal data can be used to evaluate: (a) the physiology of a membrane or tissue; (b) the operational condition or function of a body system or portion thereof (when at rest or under stimulation); and/or (c) the efficacy of a therapeutic treatment used to treat a diagnosed disorder, disease, or condition. Thus, the present invention provides methods for screening and/or diagnosing a respiratory, cardiopulmonary disorder or disease such as chronic heart failure, and/or methods for monitoring the efficacy of therapeutics administered to subject to treat the disorder or disease.
    Type: Application
    Filed: January 31, 2003
    Publication date: January 8, 2004
    Inventors: Bastiaan Driehuys, Margaret Hall, Claudio Marelli, Sven Mansson, Jan Wolber
  • Methods for in vivo evaluation of physiological conditions and/or organ or system function including methods to evaluate cardiopulmonary disorders such as chronic heart failure using polarized 129 Xe
    Publication number: 20030064023
    Abstract: In certain embodiments, methods of the present invention obtain NMR spectroscopy signal data that corresponds to the behavior of the polarized 129Xe at a selected site(s) in selected environments in vivo. The gas exchange signal data can be used to evaluate: (a) the thickness of a barrier, such as a membrane, lining, wall or width of a lumen; (b) the operational condition or function of a membrane, body system or portion thereof; (c) cerebral perfusion; and/or (c) the efficacy of a therapeutic treatment used to treat a diagnosed disorder, disease, or condition. Thus, the present invention provides methods for screening and/or diagnosing a disorder or disease, and/or methods for monitoring the efficacy of therapeutics administered to subject to treat a disorder or disease.
    Type: Application
    Filed: September 6, 2002
    Publication date: April 3, 2003
    Inventors: Bastiaan Driehuys, Margaret Hall, Claudio Marelli
  • Methods for in vivo evaluation of respiratory or cardiopulmonary disorders such as chronic heart failure using polarized 129Xe
    Publication number: 20030064024
    Abstract: In certain embodiments, methods of the present invention obtain dynamic data sets of an NMR spectroscopy signal of polarized 129Xe in a selected structure, environment, or system. The signal data can be used to evaluate: (a) the physiology of a membrane or tissue: (b) the operational condition or function of a body system or portion thereof (when at rest or under stimulation); and/or (c) the efficacy of a therapeutic treatment used to treat a diagnosed disorder, disease, or condition. Thus, the present invention provides methods for screening and/or diagnosing a respiratory, cardiopulmonary disorder or disease such as chronic heart failure, and/or methods for monitoring the efficacy of therapeutics administered to subject to treat the disorder or disease.
    Type: Application
    Filed: September 6, 2002
    Publication date: April 3, 2003
    Inventors: Bastiaan Driehuys, Margaret Hall, Claudio Marelli