Patents by Inventor Claudio Pollo
Claudio Pollo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11766560Abstract: Described herein are microelectrode array devices, and methods of fabrication, assembly and use of the same, to provide highly localized neural recording and/or neural stimulation to a neurological target. The device includes multiple microelectrode elements arranged protruding shafts. The protruding shafts are enclosed within an elongated probe shaft, and can be expanded from their enclosure. The microelectrode elements, and elongated probe shafts, are dimensioned in order to target small volumes of neurons located within the nervous system, such as in the deep brain region. Beneficially, the probe can be used to quickly identify the location of a neurological target, and remain implanted for long-term monitoring and/or stimulation.Type: GrantFiled: June 12, 2020Date of Patent: September 26, 2023Inventors: André Mercanzini, Philippe Renaud, Claudio Pollo
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Patent number: 11478633Abstract: A method and system are described for, based upon a plurality of previously-acquired directional LFP signals measured in a plurality of different directions at a directional sensor lead located in a predetermined region of a patient's brain, determining optimised patient-specific programming parameters for programming a directional stimulation lead with parameters for stimulating the said region. The method comprises a first step of determining, over at least one predetermined frequency range, a power-frequency variation curve of each of the directional LFP signals, a second step of identifying frequency peaks in the power-frequency variation curves, a third step of detecting one of the identified frequency peaks at which a maximum difference in signal power between the directional LFP signals occurs, and a fourth step of calculating a plurality of directional stimulation weighting factors on the basis of the relative signal powers of the directional LFP signals at the detected frequency peak.Type: GrantFiled: March 15, 2017Date of Patent: October 25, 2022Inventors: Gerd Tinkhauser, Peter Brown, Alek Pogosyan, Michael Schüpbach, Claudio Pollo, Ines Debove
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Publication number: 20200306523Abstract: Described herein are microelectrode array devices, and methods of fabrication, assembly and use of the same, to provide highly localized neural recording and/or neural stimulation to a neurological target. The device includes multiple microelectrode elements arranged protruding shafts. The protruding shafts are enclosed within an elongated probe shaft, and can be expanded from their enclosure. The microelectrode elements, and elongated probe shafts, are dimensioned in order to target small volumes of neurons located within the nervous system, such as in the deep brain region. Beneficially, the probe can be used to quickly identify the location of a neurological target, and remain implanted for long-term monitoring and/or stimulation.Type: ApplicationFiled: June 12, 2020Publication date: October 1, 2020Inventors: André MERCANZINI, Philippe RENAUD, Claudio POLLO
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Patent number: 10695556Abstract: Described herein are microelectrode array devices, and methods of fabrication, assembly and use of the same, to provide highly localized neural recording and/or neural stimulation to a neurological target. The device includes multiple microelectrode elements arranged protruding shafts. The protruding shafts are enclosed within an elongated probe shaft, and can be expanded from their enclosure. The microelectrode elements, and elongated probe shafts, are dimensioned in order to target small volumes of neurons located within the nervous system, such as in the deep brain region. Beneficially, the probe can be used to quickly identify the location of a neurological target, and remain implanted for long-term monitoring and/or stimulation.Type: GrantFiled: December 5, 2016Date of Patent: June 30, 2020Assignee: Ecole Polytechnique Federale de LausanneInventors: André Mercanzini, Philippe Renaud, Claudio Pollo
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Publication number: 20190030321Abstract: A method and system are described for, based upon a plurality of previously-acquired directional LFP signals measured in a plurality of different directions at a directional sensor lead located in a predetermined region of a patient's brain, determining optimised patient-specific programming parameters for programming a directional stimulation lead with parameters for stimulating the said region. The method comprises a first step of determining, over at least one predetermined frequency range, a power-frequency variation curve of each of the directional LFP signals, a second step of identifying frequency peaks in the power-frequency variation curves, a third step of detecting one of the identified frequency peaks at which a maximum difference in signal power between the directional LFP signals occurs, and a fourth step of calculating a plurality of directional stimulation weighting factors on the basis of the relative signal powers of the directional LFP signals at the detected frequency peak.Type: ApplicationFiled: March 15, 2017Publication date: January 31, 2019Applicant: UNIVERSITÄT BERNInventors: Gerd Tinkhauser, Peter Brown, Alek Pogosyan, Michael Schüpbach, Claudio Pollo, Ines Debove
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Publication number: 20170080210Abstract: Described herein are microelectrode array devices, and methods of fabrication, assembly and use of the same, to provide highly localized neural recording and/or neural stimulation to a neurological target. The device includes multiple microelectrode elements arranged protruding shafts. The protruding shafts are enclosed within an elongated probe shaft, and can be expanded from their enclosure. The microelectrode elements, and elongated probe shafts, are dimensioned in order to target small volumes of neurons located within the nervous system, such as in the deep brain region. Beneficially, the probe can be used to quickly identify the location of a neurological target, and remain implanted for long-term monitoring and/or stimulation.Type: ApplicationFiled: December 5, 2016Publication date: March 23, 2017Applicant: Ecole Polytechnique Federale de LausanneInventors: André MERCANZINI, Philippe RENAUD, Claudio POLLO
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Patent number: 9549708Abstract: Described herein are microelectrode array devices, and methods of fabrication, assembly and use of the same, to provide highly localized neural recording and/or neural stimulation to a neurological target. The device includes multiple microelectrode elements arranged protruding shafts. The protruding shafts are enclosed within an elongated probe shaft, and can be expanded from their enclosure. The microelectrode elements, and elongated probe shafts, are dimensioned in order to target small volumes of neurons located within the nervous system, such as in the deep brain region. Beneficially, the probe can be used to quickly identify the location of a neurological target, and remain implanted for long-term monitoring and/or stimulation.Type: GrantFiled: March 31, 2011Date of Patent: January 24, 2017Assignee: ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNEInventors: André Mercanzini, Philippe Renaud, Claudio Pollo
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Patent number: 8617180Abstract: The system comprises at least three anchors (2,2?,2?) intended to be attached to the patient and equipped with markers (5,5?,5?), an insertion guide device (6) with an insertion guide (7) intended to be attached to said anchors (2,2?,2?), an external calibration device (8) with at least three calibration markers (10,10?,10?) corresponding to said markers (5,5?,5?) and a planning and imaging software. The planning and imaging software is used to determine the position of a target point in the patient with respect to the markers (5,5?,5?), the calibration device is used to calibrate and orient the insertion guide (7) of the insertion guide device (6) mounted on said calibration markers (10,10?,10?) using the determination of the software before the insertion guide device is mounted on said markers (5,5?,5?) attached to the patient.Type: GrantFiled: November 5, 2008Date of Patent: December 31, 2013Assignees: Ecole Polytechnique Fédérale de Lausanne (EPFL), Université de LausanneInventors: Jean-Philippe Thiran, Claudio Pollo
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Publication number: 20130211424Abstract: The system comprises at least a support (5) to be attached to a patient by fixing means (4), said support having an outer thread (7), a first nut (9) with an inner thread (11) cooperating with said outer thread (7); and an anchor having a spherical bottom end (10) being placed between said support and said nut, a spherical head (15) said spherical bottom end and head being linked by a shaft, a second nut (16) having an inner thread (17) and intended to be screwed on an external device having a corresponding thread (31), such as a platform (20) or a surgical device (30), whereby the tightening of at least one of the nuts (9,16) on the support and/or on the external device allows to block the position of the anchor.Type: ApplicationFiled: July 23, 2010Publication date: August 15, 2013Applicants: Universite de Lausanne, Ecole Polytechnique Federale de LausanneInventors: Jean Philippe Thiran, Claudio Pollo, Rémi Charrier, David Haag
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Publication number: 20130085361Abstract: Described herein are microelectrode array devices, and methods of fabrication, assembly and use of the same, to provide highly localized neural recording and/or neural stimulation to a neurological target. The device includes multiple microelectrode elements arranged protruding shafts. The protruding shafts are enclosed within an elongated probe shaft, and can be expanded from their enclosure. The microelectrode elements, and elongated probe shafts, are dimensioned in order to target small volumes of neurons located within the nervous system, such as in the deep brain region. Beneficially, the probe can be used to quickly identify the location of a neurological target, and remain implanted for long-term monitoring and/or stimulation.Type: ApplicationFiled: March 31, 2011Publication date: April 4, 2013Inventors: André Mercanzini, Philippe Renaud, Claudio Pollo
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Publication number: 20110190789Abstract: The system comprises at least three anchors (2,2?,2?) intended to be attached to the patient and equipped with markers (5,5?,5?), an insertion guide device (6) with an insertion guide (7) intended to be attached to said anchors (2,2?,2?), an external calibration device (8) with at least three calibration markers (10,10?,10?) corresponding to said markers (5,5?,5?) and a planning and imaging software. The planning and imaging software is used to determine the position of a target point in the patient with respect to the markers (5,5?,5?), the calibration device is used to calibrate and orient the insertion guide (7) of the insertion guide device (6) mounted on said calibration markers (10,10?,10?) using the determination of the software before the insertion guide device is mounted on said markers (5,5?,5?) attached to the patient.Type: ApplicationFiled: November 5, 2008Publication date: August 4, 2011Applicant: ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL)Inventors: Jean-Philippe Thiran, Claudio Pollo