Patents by Inventor Claudio Scotti

Claudio Scotti has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Daunorubin 14-hydroxylase
    Patent number: 5786190
    Abstract: The ability to convert daunorubicin to doxorubicin can be conferred on a host cell by transformation with a recombinant vector comprising DNA encoding daunorubicin 14-hydroxylase. The host cell can then be used to produce doxorubicin.
    Type: Grant
    Filed: December 3, 1996
    Date of Patent: July 28, 1998
    Assignee: Pharmacia & Upjohn S.p.A.
    Inventors: Augusto Solari Inventi, Umberto Breme, Anna Luisa Colombo, Charles Richard Hutchinson, Sharee Otten, Claudio Scotti
  • DNA encoding daunorubicin 14-hyroxylase and method for preparing doxorubicin
    Patent number: 5695966
    Abstract: The ability to convert daunorubicin to doxorubicin can be conferred on a host cell by transformation with a recombinant vector comprising DNA encoding daunorubicin 14-hydroxylase. The host cell can then be used to produce doxorubicin.
    Type: Grant
    Filed: February 27, 1995
    Date of Patent: December 9, 1997
    Assignee: Pharmacia & Upjohn S.p.A.
    Inventors: Augusto Solari Inventi, Umberto Breme, Anna Luisa Colombo, Charles Richard Hutchinson, Sharee Otten, Claudio Scotti
  • Process for preparing daunorubicin
    Patent number: 5652125
    Abstract: The ability to improve the conversion of .epsilon.-rhodomycinone to daunorubicin can be conferred on a bacterial host transformed with a recombinant vector comprising a DNA coding for an appropriate protein useful for that conversion. Furthermore, the bacterial host may have a mutation that blocks the function of a gene of daunorubicin metabolism.
    Type: Grant
    Filed: June 10, 1996
    Date of Patent: July 29, 1997
    Assignee: Pharmacia S.p.A.
    Inventors: Claudio Scotti, Charles Richard Hutchinson, Anna Luisa Colombo, Silvia Filippini