Patents by Inventor Claudio ZAMBALDO

Claudio ZAMBALDO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NEW THIAZOLOPYRIMIDINONE DERIVATIVES
    Publication number: 20240018163
    Abstract: The invention relates to a compound of formula (I) wherein R1—R4 and A1-A3 are as defined in the description and in the claims. The compound of formula (I) can be used as a medicament.
    Type: Application
    Filed: September 15, 2023
    Publication date: January 18, 2024
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Virginie BROM, Cosimo DOLENTE, Delphine GAUFRETEAU, Nadine GRETHER, Fionn Susannah O'HARA, Matilde PIRAS, Hasane RATNI, Michael REUTLINGER, Walter VIFIAN, Claudio ZAMBALDO
  • NEW THIADIAZOLOPYRIMIDONE DERIVATIVES
    Publication number: 20240010659
    Abstract: The invention relates to a compound of formula (I) wherein R1-R4 and A1 are as defined in the description and in the claims. The compound of formula (I) can be used as a medicament.
    Type: Application
    Filed: September 15, 2023
    Publication date: January 11, 2024
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Cosimo DOLENTE, Nadine GRETHER, Fionn Susannah O'HARA, Matilde PIRAS, Hasane RATNI, Michael REUTLINGER, Walter VIFIAN, Claudio ZAMBALDO
  • THIENOPYRIMIDINONE DERIVATIVES
    Publication number: 20240002407
    Abstract: The invention relates to a compound of formula (I) wherein X, R1-R4 are as defined in the description and in the claims. The compound of formula (I) can be used as a medicament.
    Type: Application
    Filed: September 15, 2023
    Publication date: January 4, 2024
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Cosimo DOLENTE, Nadine GRETHER, Fionn Susannah O'HARA, Matilde PIRAS, Hasane RATNI, Michael REUTLINGER, Walter VIFIAN, Claudio ZAMBALDO
  • SMALL MOLECULE SCREENING CELLULAR ASSAY USING MODIFIED BEADS
    Publication number: 20220213471
    Abstract: A method for screening a DNA-encoded library of chemical structures (2) for activity in a cellular target (11) wherein the chemical structures (2) of the library, the corresponding encoding DNA (4) and, optionally, a chemical probe (7/8/9) susceptible to the response molecule (12) are covalently linked to beads (1); the method comprising providing an incubation medium (13) or aliquot thereof comprising the cellular target (11) and exactly one or more than one bead (1) as defined above, releasing the chemical structures (2) from the bead(s) (1) in the incubation medium (13) or aliquots thereof by cleaving the structure linkers (3) and incubating the released chemical structures (2) and the cellular target (11); and sequencing the encoding DNA present or remaining on the bead(s) (1). A bead (1) suited for the method is also provided.
    Type: Application
    Filed: April 15, 2020
    Publication date: July 7, 2022
    Inventors: Alexander Lee SATZ, Gregor DERNICK, Claudio ZAMBALDO