Abstract: A blinding device for administering a substance to a patient in a clinical trial is presented where the blinding device has an opaque housing to receive at least two delivery devices adapted to dispense a substance provided therein, an outlet being in fluid communication with at least one delivery device for administering the substance to a patient, and at least one actuating member mechanically engageable with at least one delivery device and being actuatable from outside the housing.

Abstract: The present invention relates to a blinding kit for administering a medicament to a patient in a clinical trial, the blinding kit comprising: a first blinding device having an opaque container and having an outlet for administering a liquid substance to a patient and having at least a first and a second inlet, wherein the first inlet is in permanent fluid communication with the outlet and wherein at least the second inlet is disconnected from the outlet, a second blinding device having an opaque container and having an outlet for administering a liquid substance to a patient and having at least two inlets, wherein said at least two inlets are in permanent fluid communication with the outlet.

Abstract: An extraction device and an extraction kit for one-time extracting a medicament from a container is presented where the extraction device has a housing adapted to non-releasably engage with the container and comprising an axially elongated receptacle, wherein the receptacle is adapted to axially guide a drug delivery device and a piercing member to a distal stop position for penetrating a seal of the container. The device and kit also have at least one fixing member to keep the piercing member in the distal stop position and to support a non-reversible disconnection of the drug delivery device from the piercing member.

Abstract: A blinding device for administering a substance to a patient in a clinical trial is presented where the blinding device has an opaque housing to receive at least two delivery devices adapted to dispense a substance provided therein, an outlet being in fluid communication with at least one delivery device for administering the substance to a patient, and at least one actuating member mechanically engageable with at least one delivery device and being actuatable from outside the housing.

Abstract: The present invention relates to a blinding kit for administering a medicament to a patient in a clinical trial, the blinding kit comprising: a first blinding device having an opaque container and having an outlet for administering a liquid substance to a patient and having at least a first and a second inlet, wherein the first inlet is in permanent fluid communication with the outlet and wherein at least the second inlet is disconnected from the outlet, a second blinding device having an opaque container and having an outlet for administering a liquid substance to a patient and having at least two inlets, wherein said at least two inlets are in permanent fluid communication with the outlet.

Abstract: A driver (DD, SD, PD1, PS1, PD2, PS2) supplies, at a frame rate, a first current (I1) with a first duty cycle being smaller than one to a first light emitting element (PL1) of an active matrix display (AMD) and a second current (I2) to a second light emitting element (PL2) of the active matrix display (AMD). The second light emitting element (PL2) has a shorter lifetime than the first light emitting element (PL1). The driver (DD, SD, PD1, PS1, PD2, PS2) limits controls the second duty cycle to be larger than the first duty cycle.

Abstract: The novel method of electronic color image processing comprises: inputting an image; obtaining a color (A) based on colors present in at least a first part of the image; and changing a saturation correlate (S2) defined with respect to the color (A) for at least a second part of the image. This allows for better quality saturation modification on a larger number of possible input images.

Abstract: A luminance and color separation filter unit (300) for extracting a luminance signal (Y) and two color signals (U, V) from a composite color television signal (CVBS).

Abstract: A luminance and color separation filter unit (300, 400, 500, 600, 700) for extracting a luminance signal (Y) and two color signals (U, V) from a composite color television signal (CVBS), comprising a chrominance (C) signal being modulated on a subcarrier which is located in the high-frequency part of the frequency spectrum of the luminance signal (Y), is disclosed. The filter unit (300, 400, 500, 600, 700) is arranged to compute at least one value of a set of values comprising an output luminance value (Y(x, n)) of a particular output pixel (x), a first color value (U(x, n)) of the particular output pixel (x) and a second color value (V(x, n)) of the particular output pixel (x) on basis of a first (F1), a second (F2) and a third (F3) sample derived from the composite color television signal (CVBS), where the first (F1), the second (F2) and the third (F3) sample have mutually different sub-carrier phases.

Abstract: In a process for producing filler-containing thermoplastic molding compositions by mixing fillers with thermoplastics in the melt,a) the fillers are mixed in a mixing apparatus in the melt with a low molecular weight thermoplastic having a melt viscosity of at most 30 Pas (measured at 20.degree. C. above the melting point of the thermoplastic compound and at a shear gradient of 1,000 s.sup.-1),b) the product thus obtained is removed from the mixing apparatus, cooled and comminuted, andc) the comminuted product is then subjected in the solid phase to a post-condensation.

Abstract: Copolyamides are prepared by a continuous process in which(a) an aqueous solution of salts of equimolar amounts of diamines and dicarboxylic acids is passed, under superatmospheric pressure and with simultaneous evaporation of water, through a tubular precondensation zone with formation of a vapor phase and a prepolymer at above the melting point of the prepolymer,(b) the vapor phase is separated from the prepolymer melt,(c) the vapor phase is separated in a column into steam and an aqueous diamine solution, and the aqueous solution containing diamines is recycled to the polymerization,(d) the prepolymer melt is mixed with molten caprolactam at polyamide-forming temperatures, and(e) the mixture of prepolymer and caprolactam is passed downward through a vertical polymerization tube at polyamide-forming temperatures and a copolyamide is obtained.

Abstract: Caprolactam and oligomers thereof are removed from nylon granules containing same in a process wherein(a) nylon granules are introduced at not less than 100.degree. C. at the top of a substantially upright treatment zone,(b) nylon granules are passed downward through the treatment zone while being heated to from 130.degree. to 210.degree. C.,(c) superheated steam is passed at from 130.degree. to 210.degree. C. upward through the treatment zone,(d) dry nylon granules are withdrawn at the bottom end of the treatment zone and steam containing caprolactam and oligomers thereof is withdrawn at the top of the treatment zone,(e) the caprolactam and oligomers thereof containing steam thus obtained is passed through a column giving an aqueous solution of caprolactam and oligomers thereof as bottom product and virtually caprolactam-free steam as overhead product.

Abstract: An improved paper-coating composition containing, per 100 parts by weight of finely divided pigment, from 5 to 25 parts by weight of one or more copolymers, having a glass transition temperature of from -40.degree. to 50.degree. C., in the form of an aqueous dispersion, and from 0.1 to 10 parts by weight of one or more water-soluble or water-swellable co-binders selected from the group comprising polyvinyl alcohol, cellulose ethers, starch, casein, alginates and high molecular weight carboxyl-containing emulsion polymers. The co-binder is added to the paper-coating composition in the form of a water-in-oil emulsion. Paper-coating compositions having high water retention are obtained, and papers coated with such compositions have improved water resistance.

Abstract: Terpolymers which have Fikentscher K-values of from 8 to 100 and comprise 50 mole percent of maleic anhydride units, from 35 to 45 mole percent of 2,4,4'-trimethylpent-1-ene units and from 5 to 15 mole percent of 2,4,4'-trimethylpent-2-ene units, and processes for their preparation by polymerizing 50 parts by weight of maleic anhydride, from 35 to 180 parts by weight of 2,4,4'-trimethylpent-1-ene and from 0.6 to 6 parts by weight of 2,4,4'-trimethylpent-2-ene per part by weight of 2,4,4'-trimethylpent-1-ene employed, in the presence of a free-radical initiator at from 60.degree. to 200.degree. C. and a pressure of from 1 to 20 bar, and separating the terpolymers from the unconverted monomers.

Abstract: A process for the preparation of modified poly-N-vinylpyrrolid-2-one containing two identical reactive groups, wherein polyvinylpyrrolidone is treated with complex hydrides, with or without further reaction of the modified polyvinylpyrrolidone with a reactive bifunctional compound, to give a polymer which has a molecular weight at least 2.5 times as great as that of the starting polymer.

Abstract: A glass-clear nylon based on aromatic dicarboxylic acids and dialicyclic diamines is prepared by polycondensing isophthalic acid with a mixture of 3,3'-dimethyl-4,4'-diamino-dicyclohexylmethane and hexamethylenediamine.The nylons may be used for the production of moldings, especially by injection-molding.

Abstract: A process for the preparation of copolymers of maleic anhydride and relatively long-chain alkenes by suspension polymerization of these monomers in the presence of a free radical initiator and a dispersant at an elevated temperature, in excess alkene as the suspension medium, wherein a poly(alkyl vinyl ether) is used as the dispersant.

Abstract: A process for the preparation of modified poly-N-vinylpyrrolid-2-one containing two identical reactive groups, wherein polyvinylpyrrolidone is treated with complex hydrides, with or without further reaction of the modified polyvinylpyrrolidone with a reactive bifunctional compound, to give a polymer which has a molecular weight at least 2.5 times as great as that of the starting polymer.

Abstract: Polyethers, preferably containing sulfone groups, are obtained by a multi-stage condensation process at from 100.degree. to 230.degree. C. from substantially equivalent amounts of bis-(4-hydroxyphenyl)-sulfone and a dichlorobenzene compound in a polar aprotic solvent in the presence of an anhydrous alkali metal carbonate, with or without the addition of a compound which forms an azeotrope.

Abstract: Polyethers are manufactured by polycondensing about equivalent amounts of a bisphenol and of a dihalogen compound in the presence of an anhydrous alkali metal carbonate, in the absence of a solvent or diluent. The polyethers may be used for the manufacture of moldings, fibers, films, adhesives and coating compositions.