Patents by Inventor Claus D. Mueller

Claus D. Mueller has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5342853
    Abstract: The use of nor-verapamil and nor-gallopamil and the salts thereof with physiologically tolerated acids is disclosed for the preparation of drugs with antiarteriosclerotic properties.
    Type: Grant
    Filed: November 12, 1991
    Date of Patent: August 30, 1994
    Assignee: Knoll AG
    Inventors: Claus D. Mueller, Liliane Unger
  • Patent number: 5118685
    Abstract: Aminopropanol derivatives of the formula: ##STR1## where R.sup.1 and R.sup.2 are identical or different and are each hydrogen, alkyl, cycloalkyl, alkenyl, alkynyl or hydroxyalkyl, each of not more than 6 carbon atoms, alkoxyalkyl, alkylthioalkyl or dialkylaminoalkyl, each of not more than 9 carbon atoms in total, or phenylalkyl or phenoxyalkyl where the alkyl radical is of not more than 6 carbon atoms and the phenyl radical is unsubstituted or substituted by alkyl or alkoxy, each of not more than 3 carbon atoms, or R.sup.1 and R.sup.2, together with the nitrogen atom which links them, form a 5-membered to 7-membered saturated heterocyclic ring which can be substituted by one or two phenyl and/or hydroxyl radicals and can contain an oxygen or nitrogen atom, as a further heteroatom in the ring, and such an additional nitrogen atom can be substituted by alkyl of 1 to 3 carbon atoms or by phenyl, and -- .circle.
    Type: Grant
    Filed: December 3, 1984
    Date of Patent: June 2, 1992
    Assignee: BASF Aktiengesellschaft
    Inventors: Albrecht Franke, Wolfgang Spiegler, Hardo Siegel, Claus D. Mueller, Gerda von Philipsborn, Dieter Lenke, Josef Gries
  • Patent number: 4777183
    Abstract: Anipamil and its salts with physiologically tolerated acids are used for the preparation of drugs having antiarteriosclerotic properties and in the treatment of arteriosclerosis.
    Type: Grant
    Filed: October 5, 1987
    Date of Patent: October 11, 1988
    Assignee: Knoll AG
    Inventors: Dieter Lenke, Claus D. Mueller
  • Patent number: 4670435
    Abstract: 10,11-Dihydro-5H-dibenzo[a,d]cycloheptadiene derivatives of the formula I ##STR1## where R.sup.1 and R.sup.2 have the meanings stated in the description, and their preparation are described. The novel substances are useful for the treatment of disorders.
    Type: Grant
    Filed: December 2, 1985
    Date of Patent: June 2, 1987
    Assignee: BASF Aktiengesellschaft
    Inventors: Albrecht Franke, deceased, Claus D. Mueller, Dieter Lenke
  • Patent number: 4618622
    Abstract: Sulfonates of hydroxycoumarins of the formula I ##STR1## where R.sup.1 and R.sup.2 are identical or different and are each hydrogen, halogen or alkyl of 1 to 5 carbon atoms which can be substituted by --NR.sup.4 R.sup.5, --OR.sup.4 or --OC(O)R.sup.4, where R.sup.4 and R.sup.5 are identical or different and are each hydrogen or alkyl of 1 to 4 carbon atoms, or R.sup.1 and R.sup.2 are each a carboxylic acid group --OC(O)R.sup.4 or a carboxamido radical, with the proviso that R.sup.1 is not methyl when R.sup.2 is hydrogen, or R.sup.1 and R.sup.2 together form a --(CH.sub.2).sub.n -- chain where n is 3-5, and R.sup.3 is a straight-chain or branched alkyl radical of 1 to 8 carbon atoms or cycloalkyl of 3 to 8 carbon atoms, each of which can be substituted by halogen, --OR.sup.4, --NR.sup.4 R.sup.5, --CN or phenyl, or R.sup.3 is a straight-chain or branched alkenyl radical of 3 to 8 carbon atoms, an amino group -- NR.sup.4 R.sup.
    Type: Grant
    Filed: November 17, 1983
    Date of Patent: October 21, 1986
    Assignee: BASF Aktiengesellschaft
    Inventors: Rainer Schlecker, Peter Schmidt, Peter C. Thieme, Dieter Lenke, Hans-Jurgen Teschendorf, Martin Traut, Claus D. Mueller, Hans P. Hofmann, Horst Kreiskott
  • Patent number: 4612320
    Abstract: Compounds of the general formula ##STR1## where R.sup.1, R.sup.2, R.sup.3, R.sup.4 and n have the meanings given in the description, are useful for treating cardiac disorders.
    Type: Grant
    Filed: March 12, 1984
    Date of Patent: September 16, 1986
    Assignee: BASF Aktiengesellschaft
    Inventors: Albrecht Franke, Josef Gries, Claus D. Mueller, Dieter Lenke
  • Patent number: 4575508
    Abstract: 2-Substituted 1-(3'-aminoalkyl)-1,2,3,4-tetrahydro-.beta.-carbolines of the formula ##STR1## where n, R.sup.1, R.sup.2, R.sup.3, R.sup.4 and R.sup.5 have the meanings given in the description, and their preparation and use.The novel substances are useful for treating arrhythmia.
    Type: Grant
    Filed: August 5, 1983
    Date of Patent: March 11, 1986
    Assignee: BASF Aktiengesellschaft
    Inventors: Gerd Steiner, Claus D. Mueller, Dieter Lenke
  • Patent number: 4571409
    Abstract: Novel aminopropanol derivatives of 2-hydroxy-.beta.-phenyl-propiophenones and their physiologically acceptable acid addition compounds, processes for their preparation and therapeutic agents which contain these derivatives and are useful as antiarrhythmic drugs.
    Type: Grant
    Filed: May 13, 1985
    Date of Patent: February 18, 1986
    Assignee: BASF Aktiengesellschaft
    Inventors: Albrecht Franke, Josef Mueller, Helmut Lietz, Walter-Wielant Wiersdorff, Hans-Guenther Hege, Claus D. Mueller, Josef Gries, Dieter Lenke, Gerda von Philipsborn, Manfred Raschack
  • Patent number: 4556662
    Abstract: Bispidine derivatives of the formula I ##STR1## where R is hydrogen or amino, and their salts with physiologically tolerated acids. The compounds have antiarrhythmic properties.
    Type: Grant
    Filed: September 30, 1983
    Date of Patent: December 3, 1985
    Assignee: BASF Aktiengesellschaft
    Inventors: Fritz Binnig, Claus D. Mueller, Manfred Raschack, Gerda von Philipsborn
  • Patent number: 4459301
    Abstract: Bispidine derivatives of the formula I ##STR1## where R is hydrogen or amino, and their salts with physiologically tolerated acids. The compounds possess antiarrhythmic properties.
    Type: Grant
    Filed: March 3, 1982
    Date of Patent: July 10, 1984
    Assignee: BASF Aktiengesellschaft
    Inventors: Fritz Binnig, Claus D. Mueller, Manfred Raschack, Gerda von Philipsborn
  • Patent number: 4438131
    Abstract: .omega.-Cyano-1,.omega.-diphenyl-azaalkane derivatives of the formula I ##STR1## where R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6, R.sup.7, R.sup.8, m and n have the meanings given in the description, and salts thereof with physiologically tolerated acids, are useful in treating cardiovascular disorders.
    Type: Grant
    Filed: March 30, 1982
    Date of Patent: March 20, 1984
    Assignee: BASF Aktiengesellschaft
    Inventors: Oskar Ehrmann, Manfred Raschack, Josef Gries, Rolf Kretzschmar, Hans D. Lehmann, Ludwig Friedrich, Dirk Wuppermann, Frank Zimmermann, Werner Seitz, Hans J. Treiber, Ferdinand Dengel, Wolfram Frank, Hans-Georg Kurbjuweit, Claus D. Mueller
  • Patent number: 4329352
    Abstract: Substituted piperidino-alkyl ethers of 3-hydroxy-thiophene-2-carboxylic acid esters and their physiologically tolerated addition salts with acids, processes for their preparation, and pharmaceutical formulations which contain these compounds and which may be used in the treatment of cardiac arrhythmias.
    Type: Grant
    Filed: December 3, 1980
    Date of Patent: May 11, 1982
    Assignee: BASF Aktiengesellschaft
    Inventors: Fritz-Frieder Frickel, Gerda von Philipsborn, Claus D. Mueller, Dieter Lenke
  • Patent number: 4315939
    Abstract: Substituted piperidinoalkyl ethers of 4,5-dialkyl-3-hydroxy-pyrrole-2-carboxylic acid esters and their physiologically tolerated addition salts with acids, processes for their preparation and pharmaceutical formulations which contain these compounds and are useful in the treatment of cardiac arrhythmias.
    Type: Grant
    Filed: October 6, 1980
    Date of Patent: February 16, 1982
    Assignee: BASF Aktiengesellschaft
    Inventors: Fritz-Frieder Frickel, Albrecht Franke, Gerda Von Philipsborn, Claus D. Mueller, Dieter Lenke
  • Patent number: 4288449
    Abstract: Compounds of the formula 1 ##STR1## where R.sup.1 is a saturated, unsubstituted or substituted aliphatic radical of 1 to 8 carbon atoms, an unsaturated alkyl radical of 2 to 8 carbon atoms, a cycloalkyl radical of 3 to 7 carbon atoms in the ring or an alkyl radical of 1 to 4 carbon atoms which is substituted by phenyl or by a 5- or 6-membered aromatic heterocyclic ring containing an N, O or S atom, the phenyl ring or the heterocyclic ring itself being unsubstituted, monosubstituted or polysubstituted, andR.sup.2 is hydrogen orR.sup.1 and R.sup.2 together with the nitrogen are a 4-membered to 6-membered cycloaliphatic saturated heterocyclic ring,R.sup.3 is hydrogen or alkyl of 1 to 5 carbon atoms,R.sup.4 and R.sup.
    Type: Grant
    Filed: May 28, 1980
    Date of Patent: September 8, 1981
    Assignee: BASF Aktiengesellschaft
    Inventors: Jens-Uwe Bliesener, Karl-Heinz Geiss, Dieter Lenke, Claus D. Mueller