Patents by Inventor Claus Dambmann

Claus Dambmann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for producing cheese
    Patent number: 5863573
    Abstract: A process for producing cheese, in which an enzyme preparation comprising a specific protease is added to cheese milk in the course of the process.
    Type: Grant
    Filed: August 18, 1994
    Date of Patent: January 26, 1999
    Assignee: Novo Nordisk A/S
    Inventors: Claus Dambmann, Peter Budtz, Steen Bennike Mortensen
  • Enzyme with protease activity
    Patent number: 5854050
    Abstract: A DNA construct comprising a DNA sequence encoding an enzyme exhibiting protease activity, which DNA sequence comprises the DNA sequence shown in SEQ ID No. 1 or 2 or an analog of any of these sequences being at least 80% homologous to the DNA sequence shown in SEQ ID No. 1 or 2. The proteases encoded by the DNA sequences have an acid pH optimum.
    Type: Grant
    Filed: February 1, 1996
    Date of Patent: December 29, 1998
    Assignee: Novo Nordisk A/S
    Inventors: Henrik Dalb.o slashed.ge, Stephan Christgau, Lene Nonboe Andersen, Lene Venke Kofod, Markus Sakari Kauppinen, Jack Bech Nielsen, Claus Dambmann
  • DNA constructs and methods of producing xylanolytic enzymes
    Patent number: 5770424
    Abstract: The present invention is directed to isolated nucleic acid constructs comprising a nucleic acid sequence encoding xylanolytic enzymes derived from a strain of Bacillus agaradherens, recombinant vectors and host cells comprising such constructs, and methods for obtaining xylanolytic enzymes.
    Type: Grant
    Filed: August 16, 1996
    Date of Patent: June 23, 1998
    Assignee: NovoNordisk A/S
    Inventors: Helle Outtrup, Claus Dambmann, Arne Agerlin Olsen, Henrik Bisg.ang.rd-Frantzen, Martin Schulein, Per Linaa Jorgensen
  • Alkalophilic bacillus SP. AC13 and protease, xylanase, cellulase obtainable therefrom
    Patent number: 5741693
    Abstract: The present invention relates to proteases obtained from a strain of Bacillus sp. AC13, and having (a) an apparent molecular weight of approximately 30 kD as determined by SDS-PAGE; (b) an isoelectric point of approximately 9.3 as determined by isoelectric focusing on LKB Ampholine PAG plates; (c) a pH optimum above 10 determined at 25.degree. C. with casein as substrate; (d) a temperature optimum in the range of 45.degree.-55.degree. C. determined at pH 9.5 with casein as substrate; and (e) immunochemical properties identical or partially identical to those of a protease derived from Bacillus sp. AC13, NCIMB No. 40482.
    Type: Grant
    Filed: November 30, 1994
    Date of Patent: April 21, 1998
    Assignee: Novo Nordisk A/S
    Inventors: Helle Outtrup, Claus Dambmann, Arne Agerlin Olsen, Henrik Bisg.ang.rd-Frantzen, Martin Schulein
  • Alkalophilic Bacillus sp. AC13 and protease, xylanase, cellulase obtainable therefrom
    Patent number: 5696068
    Abstract: The present invention relates to novel microorganisms, novel enzymes obtainable herefrom, and to a method of producing the novel enzymes. More specifically, the invention relates to novel enzymes obtainable from strains of the novel alkalophilic species Bacillus sp. AC13. Moreover, the invention relates to a method for producing the enzymes of the invention, and to the use of the enzymes in detergents or in the paper pulp industry.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: December 9, 1997
    Assignee: Novo Nordisk A/S
    Inventors: Helle Outtrup, Claus Dambmann, Arne Agerlin Olsen, Henrik Bisg.ang.rd-Frantzen, Martin Schulein
  • Promoter element and signal peptide of a gene encoding a Bacillus alkaline protease and vectors comprising same
    Patent number: 5650326
    Abstract: The invention is directed to an isolated nucleic acid construct(s) comprising a nucleic acid sequence encoding an alkaline protease having a molecular weight of about 34 kD and is obtainable from a strain of Bacillus sp. Group I, as well as recombinant vectors and host cells comprising such constructs. Additionally, the invention is directed to a method for obtaining the protease. The invention is also directed to promoter and signal sequences derived from said alkaline protease as well as methods of using the promoter and signal sequences in the expression of heterologous nucleic acid sequences encoding heterologous proteins in bacteria.
    Type: Grant
    Filed: June 2, 1995
    Date of Patent: July 22, 1997
    Assignees: Novo Nordisk Biotech, Inc., Novo Nordisk A/S
    Inventors: Alan P. Sloma, Helle Outtrup, Claus Dambmann, Dorrit Anita Aaslyng
  • Alkaline proteases obtainable from Bacillus sp. JA16-38A
    Patent number: 5650315
    Abstract: An alkaline serine protease is disclosed which is obtainable from Bacillus sp. JA16-38A, NCIMB No. 40263 and which (a) has a pH optimum in the range of 9-11 determined at 25.degree. C.; (b) has a temperature optimum in the range of 40.degree.-50.degree. C. determined at pH 9.5; (c) is active in the presence of ethylene-diamine tetraacetate; and (d) has a mass of about 28 kD determined by SDS-PAGE. Detergent additives and detergent compositions comprising said protease and methods for producing said protease are also disclosed.
    Type: Grant
    Filed: August 18, 1993
    Date of Patent: July 22, 1997
    Assignee: Novo Nordisk A/S
    Inventors: Helle Outtrup, Claus Dambmann, Dorrit A. Aaslyng
  • Method for the production of heterologous polypeptides using a promoter element and signal peptide of a bacillus gene encoding an alkaline protease
    Patent number: 5622841
    Abstract: The invention is directed to an isolated nucleic acid construct(s) comprising a nucleic acid sequence encoding an alkaline protease having a molecular weight of about 34 kD and is obtainable from a strain of Bacillus sp. Group I, as well as recombinant vectors and host cells comprising such constructs. Additionally, the invention is directed to a method for obtaining the protease. The invention is also directed to promoter and signal sequences derived from said alkaline protease as well as methods of using the promoter and signal sequences in the expression of heterologous nucleic acid sequences encoding heterologous proteins in bacteria.
    Type: Grant
    Filed: June 2, 1995
    Date of Patent: April 22, 1997
    Assignees: Novo Nordisk Biotech, Inc., Novo Nordisk A/S
    Inventors: Alan P. Sloma, Helle Outtrup, Claus Dambmann, Dorrit A. Aaslyng
  • Recombinant methods for the production of a bacillus alkaline protease
    Patent number: 5622850
    Abstract: The invention is directed to an isolated nucleic acid construct(s) comprising a nucleic acid sequence encoding an alkaline protease having a molecular weight of about 34 kD and is obtainable from a strain of Bacillus sp. Group I, as well as recombinant vectors and host cells comprising such constructs. Additionally, the invention is directed to a method for obtaining the protease. The invention is also directed to promoter and signal sequences derived from said alkaline protease as well as methods of using the promoter and signal sequences in the expression of heterologous nucleic acid sequences encoding heterologous proteins in bacteria.
    Type: Grant
    Filed: June 2, 1995
    Date of Patent: April 22, 1997
    Assignees: Novo Nordisk Biotech, Inc., Novo Nordisk A/S
    Inventors: Alan P. Sloma, Helle Outtrup, Claus Dambmann, Dorrit A. Aaslyng
  • Nucleic acid constructs for the production of a Bacillus alkaline protease
    Patent number: 5621089
    Abstract: The invention is directed to an isolated nucleic acid construct(s) comprising a nucleic acid sequence encoding an alkaline protease having a molecular weight of about 34 kD and is obtainable from a strain of Bacillus sp. Group I, as well as recombinant vectors and host cells comprising such constructs. Additionally, the invention is directed to a method for obtaining the protease. The invention is also directed to promoter and signal sequences derived from said alkaline protease as well as methods of using the promoter and signal sequences in the expression of heterologous nucleic acid sequences encoding heterologous proteins in bacteria.
    Type: Grant
    Filed: May 3, 1995
    Date of Patent: April 15, 1997
    Assignees: Novo Nordisk Biotech, Inc., Novo Nordisk A/S
    Inventors: Alan P. Sloma, Helle Outtrup, Claus Dambmann, Dorrit A. Aaslyng
  • Alkaline protease from bacillus sp. PD498, method of making and method of use
    Patent number: 5597720
    Abstract: An alkaline protease has been isolated from Bacillus sp. PD 498 which has a mass of 34 kD by SDS-PAGE, a pH optimum of 9-11, a pI of 9.3, and a temperature optimum of 40.degree.-55.degree. C. The protease has been formulated into detergent additives and detergents and is suitable for washing processes.
    Type: Grant
    Filed: October 26, 1994
    Date of Patent: January 28, 1997
    Assignee: Novo Nordisk A/S
    Inventors: Helle Outtrup, Claus Dambmann, Dorrit A. Aaslyng
  • Novel proteases
    Patent number: 5531918
    Abstract: The present invention relates to proteases obtained from a strain of Bacillus sp. PD138, detergent additives and compositions comprising a Bacillus sp. PD138 protease, and methods of making and using a Bacillus sp. PD138 protease.
    Type: Grant
    Filed: August 22, 1994
    Date of Patent: July 2, 1996
    Assignee: Novo Nordisk A/S
    Inventors: Helle Outtrup, Claus Dambmann, Dorrit A. Aaslyng, Poul Lindegaard
  • Detergent enzymes
    Patent number: 5468416
    Abstract: This inventions is in the field of detergent enzymes. More specifically, the invention relates to the use of proteases from fungi of the genus Verticillium for detergent purposes.
    Type: Grant
    Filed: February 8, 1994
    Date of Patent: November 21, 1995
    Assignee: Novo Nordisk A/S
    Inventors: Helle Outtrup, Dorrit A. Aaslyng, Claus Dambmann, Shamkant A. Patkar
  • Alkaline protease Bacillus sp. JP 395, method of making and detergent compositions
    Patent number: 5466594
    Abstract: An alkaline protease from a strain of Bacillus sp. JP 395 has been isolated. The protease has a mass of about 30 kDa as determined by SDS-PAGE, a pH optimum of about 9-11, a temperature optimum of about 50.degree.-65.degree. C., and an isoelectric point above 9.5. The protease is inhibited by PMSF (phenylmethylsulfonylfluoride), but not by EDTA or soybean protein inhibitor. The protease is prepared by growing this strain of bacillus in a suitable media and recovering the protease. The protease has been formulated in detergents and is stable at 40.degree. C. for 60 minutes in these detergents under wash conditions in the presence or absence of bleaches such as perborate.
    Type: Grant
    Filed: September 23, 1993
    Date of Patent: November 14, 1995
    Assignee: Nove Nordisk A/S
    Inventors: Helle Outtrup, Claus Dambmann, Margrethe Christiansen, Dorrit A. Aaslyng
  • Proteases
    Patent number: 5362414
    Abstract: This invention is in the field of detergent proteases derived from strains of a new Bacillus sp. More specifically, the invention is directed towards a protease derived from a strain of Bacillus sp. TY 145. Moreover, the invention is directed towards a process for the preparation of the protease the use of the protease enzyme, and detergent composition comprising the protease of the invention.
    Type: Grant
    Filed: August 18, 1993
    Date of Patent: November 8, 1994
    Assignee: Novo Nordisk A/S
    Inventors: Helle Outtrup, Claus Dambmann, Poul Lindegaard
  • Alkaline protease from Bacillus J 20
    Patent number: 5358865
    Abstract: An alkaline protease isolated from a strain of Bacillus sp. J 20 is disclosed. The protease has a mass of about 29 kD, a pI of about 8.8, a pH optimum above 10, and a temperature optimum of about 45.degree. to 65.degree. C. The use of the protease as a detergent enzyme, as well as detergent compositions and detergent additives comprising the protease is also disclosed.
    Type: Grant
    Filed: February 22, 1993
    Date of Patent: October 25, 1994
    Assignee: Novo Nordisk A/S
    Inventors: Helle Outtrup, Claus Dambmann, Dorrit A. Aaslyng