Patents by Inventor Claus Graff

Claus Graff has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11160487
    Abstract: A method for analyzing a condition of a heart, comprises receiving a plurality of electric signals, which are acquired by non-invasive measurement on the skin of a person or animal, each signal representing electrical activity in a respective region of the heart of the person or animal; calculating a derivative value of each signal at a plurality of time instances; selecting a plurality of the calculated derivative values of a first signal and determining a first point in time of a first event based on the selected derivative values; selecting a plurality of the calculated derivative values of a second signal and determining a second point in time of a second event, corresponding to the first event, based on the selected derivative values of the second signal, and calculating at least one measure based on a difference of the first point in time and the second point in time.
    Type: Grant
    Filed: November 3, 2017
    Date of Patent: November 2, 2021
    Assignee: AALBORG UNIVERSITET
    Inventors: Jacob Melgaard, Johannes Jan Struijk, Claus Graff
  • Publication number: 20190254552
    Abstract: A method for analyzing a condition of a heart, comprises receiving a plurality of electric signals, which are acquired by non-invasive measurement on the skin of a person or animal, each signal representing electrical activity in a respective region of the heart of the person or animal; calculating a derivative value of each signal at a plurality of time instances; selecting a plurality of the calculated derivative values of a first signal and determining a first point in time of a first event based on the selected derivative values; selecting a plurality of the calculated derivative values of a second signal and determining a second point in time of a second event, corresponding to the first event, based on the selected derivative values of the second signal, and calculating at least one measure based on a difference of the first point in time and the second point in time.
    Type: Application
    Filed: November 3, 2017
    Publication date: August 22, 2019
    Applicant: AALBORG UNIVERSITET
    Inventors: Jacob MELGAARD, Johannes Jan STRUIJK, Claus GRAFF
  • Patent number: 8684943
    Abstract: A method, system, stethoscope and server for classifying a cardiovascular sound recorded from a living subject. The method comprises the steps of: identifying diastolic and/or systolic segments of the cardiovascular sound; dividing at least one of the identified diastolic and/or systolic segments into a number of sub-segments comprising at least a first sub-segment and at least a second sub-segment; extracting from the first sub-segment at least a first signal parameter characterizing a first property of the cardiovascular sound, extracting from the second sub-segment at least a second signal parameter characterizing a second property of the cardiovascular sound; and classifying the cardiovascular sound using the at least first signal parameter and the at least second signal parameter in a multivariate classification method.
    Type: Grant
    Filed: June 26, 2007
    Date of Patent: April 1, 2014
    Assignee: Acarix A/S
    Inventors: Samuel Emil Schmidt, Johannes Jan Struijk, Claus Graff
  • Patent number: 8469896
    Abstract: This invention describes a method for dividing a substantial cycli cardiovascular signal into segments by determining the characteristics of said cyclic signal, wherein each cycle in said signal comprises at least two characteristic segments and wherein the method comprises the steps o identifying segments in a cycle based on prior knowledge of said segment characteristics and the step of verifying said identified segments based on a number of statistical parameters obtained from prior knowledge relating to said cyclic signal. Furthermore, the invention describes a system adapted to perform the above-described method.
    Type: Grant
    Filed: June 26, 2006
    Date of Patent: June 25, 2013
    Assignee: Acarix A/S
    Inventors: Samuel Emil Schmidt, Claus Graff, Johannes Jan Struijk
  • Patent number: 8260406
    Abstract: A system and a method for analysis of ECG curvature, which system involves a mathematical analysis comprising the following features where a number of different parameters are isolated and stored in a computer, where a first number of parameters are selected from at least one main group, where the selected parameters are combined in at least a first mathematical analysis. It is the object of the invention to improve mathematical analysis of ECG curvature particular for complex parts of the curvature such as notches or concavities. This can be achieved by selecting parameters from groups of symmetry, flatness, duration and/or complexity, using the parameters as input to an algorithm, where concavity intervals are evaluated on subsegments of the ECG segment and form the basis of up and downwards concavity quantification, where the system based on an algorithm detects and quantifies concavity on ECG curvatures.
    Type: Grant
    Filed: November 28, 2007
    Date of Patent: September 4, 2012
    Assignee: Aalborg Universitet
    Inventors: Thomas Bork Hardahl, Claus Graff, Mads Peter Andersen, Egon Toft, Johannes Jan Struijk, Joel Q. Xue
  • Patent number: 7991458
    Abstract: The present invention relates to a system or method for analyzing drug influence on ECG curvature and Long QT Syndrome. The system has an input means connected to an ECG source, where different parameters of a received ECG curvature are indicated and/or isolated for indicating possible symptoms which relate to certain diseases that influence the ECG curvature. The aim of the invention is to achieve a system and a method for diagnosing Long QT Syndrome in an objective, fast and effect way by indication of a number of symptoms derivable from an ECG curve. Further aim is to achieve an effective test of drug influence on ECG curvature. The system analyzes the QT curvature of the ECG curvature for indicating Long QT Syndrome.
    Type: Grant
    Filed: October 20, 2004
    Date of Patent: August 2, 2011
    Assignee: Aalborg Universitet
    Inventors: Thomas Bork Hardahl, Claus Graff, Mads Peter Andersen, Egon Toft, Johannes Jan Struijk, Joergen Kim Kanters
  • Patent number: 7840259
    Abstract: A method for evaluating an electrocardiogram is disclosed herein. The method includes measuring an electrical activity of a patient, processing the measured electrical activity to form a multi-lead signal, and extracting a segment of the multi-lead signal. The method for evaluating an electrocardiogram also includes transforming the segment of the multi-lead signal into a synthesized signal that is most representative of the patient's electrical activity, and evaluating the synthesized signal. A corresponding system for evaluating an electrocardiogram is also disclosed.
    Type: Grant
    Filed: January 11, 2007
    Date of Patent: November 23, 2010
    Assignee: General Electric Company
    Inventors: Joel Qiuzhen Xue, Johannes Jan Struijk, Mads Peter Andersen, Claus Graff, Thomas Bork Hardahl
  • Publication number: 20100160807
    Abstract: The present invention relates to a method for classifying a cardiovascular sound recorded from a living subject. The method comprises the steps of: identifying diastolic and/or systolic segments of said cardiovascular sound; dividing at least one of said identified diastolic and/or systolic segments into a number of sub-segments comprising at least a first sub-segment and at least a second sub-segment; extracting from said first sub-segment at least a first signal parameter characterizing a first property of said cardiovascular sound, extracting from said second sub-segment at least a second signal parameter characterizing a second property of said cardiovascular sound; classifying said cardiovascular sound using said at least first signal parameter and said at least second signal parameter in a multivariate classification method.
    Type: Application
    Filed: June 26, 2007
    Publication date: June 24, 2010
    Inventors: Samuel Emil Schmidt, Johannes Struijk, Claus Graff
  • Publication number: 20100145210
    Abstract: The present application relates to a method for classifying a cardiovascular sound recorded from a living subject. The method comprises the step of extracting at least two signal parameters (309) from said cardiovascular sound, said at least two signal parameters characterizes at least two different properties of at least a part of said cardiovascular sound. The method further comprises the step of classifying said cardiovascular sound using said at least two signal parameters in a multivariate classification method (310). Furthermore, the application relates to a system, stethoscope and server for classifying a cardiovascular sound recorded from a living subject, where the above-described method has been implemented.
    Type: Application
    Filed: June 26, 2006
    Publication date: June 10, 2010
    Inventors: Claus Graff, Samuel Schmidt, Johannes Struijk
  • Publication number: 20100103349
    Abstract: A backlight of the present invention (illumination device) 2 includes: light sources (5); light guide plates (7) for causing surface emission of light from the light sources (5); and a diffusing plate (8) for diffusing light from the light guide plates (7), the diffusing plate (8) facing a light-emitting surface (7a) of each of the light guide plates (7) at a predetermined distance. Each light guide plate (7) includes: a light-emitting section (7b) having the light-emitting surface (7a); and a light guide section (7c) for guiding, to the light-emitting section (7b), light from a corresponding light source (5), where the light-emitting section of one of any adjacent two light guide plates is placed over the light guide section (7c) of the other light guide plate (7). The illumination device further includes at least one maintaining section between the light-emitting surface (7a) and the diffusing plate (8), the maintaining section (10) maintaining the predetermined distance.
    Type: Application
    Filed: July 16, 2008
    Publication date: April 29, 2010
    Inventors: Samuel Emil Schmidt, Claus Graff, Johannes Jan Struijk
  • Publication number: 20100106038
    Abstract: This invention describes a method for dividing a substantial cycli cardiovascular signal into segments by determining the characteristics of said cyclic signal, wherein each cycle in said signal comprises at least two characteristic segments and wherein the method comprises the steps o identifying segments in a cycle based on prior knowledge of said segment characteristics and the step of verifying said identified segments based on a number of statistical parameters obtained from prior knowledge relating to said cyclic signal. Furthermore, the invention describes a system adapted to perform the above-described method.
    Type: Application
    Filed: June 26, 2006
    Publication date: April 29, 2010
    Inventors: Samuel Emil Schmidt, Claus Graff, Johnnes Jan Struijk
  • Publication number: 20100069767
    Abstract: The present invention relates to a system and a method for analysis of ECG curvature, which system involves a mathematical analysis, which analysis comprises the following features where a number of different parameters are isolated and stored in computer means, where a first number of parameters are selected from at least one main group, where the selected parameters are combined in at least a first mathematical analysis. It is the object of the invention to improve mathematical analysis of ECG curvature particular for complex parts of the curvature such as notches or concavities. It is a further object of the invention to improve automatic quantification of symmetry, flatness and durations of ECG curvature.
    Type: Application
    Filed: November 28, 2007
    Publication date: March 18, 2010
    Applicant: AALBORG UNIVERSITET
    Inventors: Thomas Bork Hardahl, Claus Graff, Mads Peter Andersen, Egon Toft, Johannes Jan Struijk, Joel Q. Xue
  • Patent number: 7477936
    Abstract: A system or a method for analysing ECG curvature wherein at least one among a number of different parameters is isolated, for indicating symptoms of diseases having influence on the ECG curvature. The system and method provides for objective, fast and effective indication of a number of symptoms derivable from an ECG curve which may be indicative of one or more diseases. This can be achieved when a first number of selected parameters are combined in at least a first mathematical analysis, where the result of the analysis can be represented as a point in a coordinate system comprising at least two axes where the system can compare the actual placement in the coordinate system with a number of reference parameters stored in the system for indicating diseases having influence on the ECG curvature.
    Type: Grant
    Filed: December 20, 2004
    Date of Patent: January 13, 2009
    Assignee: Aalborg Universitet
    Inventors: Thomas Bork Hardahl, Claus Graff, Mads Peter Andersen, Egon Toft, Johannes Jan Struijk, Jørgen Kim Kanters
  • Publication number: 20080154143
    Abstract: A method for evaluating an electrocardiogram is disclosed herein. The method includes measuring an electrical activity of a patient, processing the measured electrical activity to form a multi-lead signal, and extracting a segment of the multi-lead signal. The method for evaluating an electrocardiogram also includes transforming the segment of the multi-lead signal into a synthesized signal that is most representative of the patient's electrical activity, and evaluating the synthesized signal. A corresponding system for evaluating an electrocardiogram is also disclosed.
    Type: Application
    Filed: January 11, 2007
    Publication date: June 26, 2008
    Applicant: GENERAL ELECTRIC COMPANY
    Inventors: Joel Qiuzhen Xue, Johannes Jan Struijk, Mads Peter Andersen, Claus Graff, Thomas Bork Hardahl
  • Publication number: 20070208264
    Abstract: The present invention relates to a system or a method for analysing drug influence on ECG curvature and Long QT Syndrome where at least one among a number of different parameters is isolated, which system has a input means connected to an ECG source, where the different parameters of a received ECG curvature and indicated and/or isolated and for indicating possible symptoms which relates to or are indications of certain diseases, where said diseases are known to influence the ECG curvature. The aim of the invention is to achieve a system and a method for diagnosing Long QT Syndrome in an objective, fast and effective way by indication of a number of symptoms derivable from an ECG curve. Further aim of the invention is to achieve an effective test of drug influence on ECG curvature.
    Type: Application
    Filed: October 20, 2004
    Publication date: September 6, 2007
    Applicant: Aalborg Universitet
    Inventors: Thomas Hardahl, Claus Graff, Mads Andersen, Egon Toft, Johannes Struijk, Joergen Kanters
  • Publication number: 20050177049
    Abstract: A system or a method for analysing ECG curvature is provided, in which where at least one among a number of different parameters is isolated. The system has an input device connected to an ECG source, where the different parameters of a received ECG curvature are indicated and/or isolated and for indicating possible symptoms which relate to or are indications of certain diseases, where said diseases are known to influence the ECG curvature. The system and method provides for objective, fast and effective indication of a number of symptoms derivable from an ECG curve which may be indicative of one or more diseases.
    Type: Application
    Filed: December 20, 2004
    Publication date: August 11, 2005
    Inventors: Thomas Hardahl, Claus Graff, Mads Andersen, Egon Toft, Johannes Struijk, Jorgen Kanters