Patents by Inventor Claus Hallwirth

Claus Hallwirth has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • AAV capsid polynucleotides and polypeptides and virions containing the same
    Patent number: 12286457
    Abstract: The present disclosure relates generally to polypeptides derived from marsupial adeno-associated vims (AAV). The disclosure is also related to nucleic acid molecules encoding the polypeptides, and vectors comprising the nucleic acid molecules, and AAV vectors comprising the polypeptides. The disclosure also relates to uses of the nucleic acid molecules, polypeptides and AAV vectors, such as for capsid diversification.
    Type: Grant
    Filed: May 31, 2019
    Date of Patent: April 29, 2025
    Assignees: Children's Medical Research Institute, The Sydney Children's Hospital Network (Randwick and Westmead) (Incorporating the Royal Alexandra Hospital for Children
    Inventors: Claus Hallwirth, Ian Alexander
  • AAV POLYNUCLEOTIDES, POLYPEPTIDES AND VIRIONS
    Publication number: 20210122789
    Abstract: The present disclosure relates generally to polypeptides derived from marsupial adeno-associated vims (AAV). The disclosure is also related to nucleic acid molecules encoding the polypeptides, and vectors comprising the nucleic acid molecules, and AAV vectors comprising the polypeptides. The disclosure also relates to uses of the nucleic acid molecules, polypeptides and AAV vectors, such as for capsid diversification.
    Type: Application
    Filed: May 31, 2019
    Publication date: April 29, 2021
    Applicants: Children's Medical Research Institute, The Sydney Children's Hospitals Network (Randwick and Westmead) (Incorporating the Royal Alexandra
    Inventors: Claus HALLWIRTH, Ian ALEXANDER
  • Adeno-associated virus polynucleotides, polypeptides and virions
    Patent number: 10882886
    Abstract: Polypeptides are encoded by an adeno-associated virus (AAV)-derived endogenous viral element (mAAV-EVE1) found within the germline of numerous closely-related marsupial species. Nucleic acid molecules encode the polypeptides. Vectors can include the nucleic acid molecules, and recombinant AAV virions can include the polypeptides. A chimeric capsid protein can also include an MAAV-EVE1 polypeptide.
    Type: Grant
    Filed: May 3, 2017
    Date of Patent: January 5, 2021
    Assignees: CHILDREN'S MEDICAL RESEARCH INSTITUTE, THE SYDNEY CHILDREN'S HOSPITALS NETWORK (RANDWICK AND WESTMEAD) (INCORPORATING THE ROYAL ALEXANDRA HOSPITAL FOR CHILDREN), THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (WASHINGTON DC)
    Inventors: Claus Hallwirth, Ian Alexander, Richard Smith, Robert Kotin
  • ADENO-ASSOCIATED VIRUS POLYNUCLEOTIDES, POLYPEPTIDES AND VIRIONS
    Publication number: 20190135870
    Abstract: Polypeptides are encoded by an adeno-associated virus (AAV)-derived endogenous viral element (mAAV-EVE1) found within the germline of numerous closely-related marsupial species. Nucleic acid molecules encode the polypeptides. Vectors can include the nucleic acid molecules, and recombinant AAV virions can include the polypeptides. A chimeric capsid protein can also include an MAAV-EVE1 polypeptide.
    Type: Application
    Filed: May 3, 2017
    Publication date: May 9, 2019
    Applicants: Children's Medical Research Institute, The Sydney Children's Hospitals Network (Randwick and Westmead) (incorporating The Royal Alexanndra, The United States of America, as represented by the Secretary, Department of Health and Human
    Inventors: Claus Hallwirth, Ian Alexander, Richard Smith, Robert Kotin