Patents by Inventor Claus Holst-Hansen

Claus Holst-Hansen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Inhibition of invasive remodelling
    Publication number: 20080171691
    Abstract: Invasive remodelling in a mammal may be inhibited by (1) inhibiting or abolishing the protein cleaving action of plasmin and (2) inhibiting or abolishing the protein cleaving action of at least one additional proteolytic enzyme active in invasive remodelling, such as a metalloprotease.
    Type: Application
    Filed: January 24, 2008
    Publication date: July 17, 2008
    Inventors: Leif Roge Lund, Keld Dano, Ross Stephens, Nils Brunner, Helene Solberg, Claus Holst-Hansen, John Romer Nielsen
  • Peptide antagonists of the human urokinase receptor and method for selecting them
    Patent number: 7026282
    Abstract: A novel set of inhibitors of the binding interaction between human urokinase plasminogen activator (uPA) and its cell surface receptor (uPAR) has been developed. The inhibitors comprise of peptide fragments, monomeric or in multiple copies attached to a common scaffold, in which the amino acid sequence may include uncommon substituted amino acids to partially comprise of peptoid sequences. The present invention also relates to the use of such peptides in therapy, in particular for the treatment of cancer, having developed a modified non-human mammalian receptor to which the novel inhibitors are antagonistic.
    Type: Grant
    Filed: July 1, 1999
    Date of Patent: April 11, 2006
    Assignee: Cancerforskningsfonden AF 1989 (Fonden Til Fremme AF Exsperimentel Cancerforskning)
    Inventors: Michael Ploug, Søren Østergaard, Claus Holst-Hansen, Ross Stephens, Keld Danø, Arne Holm
  • Inhibition of invasive remodelling
    Publication number: 20050137121
    Abstract: Invasive remodelling in a mammal may be inhibited by (1) inhibiting or abolishing the protein cleaving action of plasmin and (2) inhibiting or abolishing the protein cleaving action of at least one additional proteolytic enzyme active in invasive remodelling, such as a metalloprotease.
    Type: Application
    Filed: September 29, 2004
    Publication date: June 23, 2005
    Inventors: Leif Lund, Keld Dano, Ross Stephens, Nils Brunner, Helene Solberg, Claus Holst-Hansen, John Nielsen
  • Inhibition of invasive remodelling
    Publication number: 20020099004
    Abstract: Invasive remodelling in a mammal may be inhibited by (1) inhibiting or abolishing the protein cleaving action of plasmin and (2) inhibiting or abolishing the protein cleaving action of at least one additional proteolytic enzyme active in invasive remodelling, such as a metalloprotease.
    Type: Application
    Filed: November 29, 2001
    Publication date: July 25, 2002
    Inventors: Leif Roge Lund, Keld Dano, Ross Stephens, Nils Brunner, Helene Solberg, Claus Holst-Hansen, John Romer Nielsen